Zobrazeno 1 - 10
of 5 200
pro vyhledávání: '"sirt3"'
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract The silencing regulatory factor 2-like protein 3 (SIRT3) is a nicotinamide adenine dinucleotide (NAD+) dependent deacetylase located primarily in the mitochondria. This protein plays an important role in oxidative stress, energy metabolism,
Externí odkaz:
https://doaj.org/article/66d23cd1b2574c29a0706a8e354fd423
Autor:
Atta Ullah, Najeeb Ur Rehman, Waseem Ul Islam, Faizullah Khan, Muhammad Waqas, Sobia Ahsan Halim, Afnan Jan, Abdullatif Bin Muhsinah, Ajmal Khan, Ahmed Al-Harrasi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Sirtuin 3 (SIRT3) belongs to the Sirtuin protein family, which consists of NAD+-dependent lysine deacylase, involved in the regulation of various cellular activities. Dysregulation of SIRT3 activity has been linked to several types of cancer
Externí odkaz:
https://doaj.org/article/cbb85a1328c244318fd27eac738f6537
Autor:
Camilla Anastasio, Isabella Donisi, Vitale Del Vecchio, Antonino Colloca, Luigi Mele, Celestino Sardu, Raffaele Marfella, Maria Luisa Balestrieri, Nunzia D’Onofrio
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-21 (2024)
Abstract Background Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of some cancer cells. However, the mechanism(s) remains to be fully eluc
Externí odkaz:
https://doaj.org/article/e2fa19d6fd6d4158838547c43ac32f7f
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Bawei Chenxiang Wan (BCW) is among the most effective and widely used therapies for coronary heart disease and angina pectoris in Tibet. However, whether it confers protection through a right-ventricle (RV) myocardial metabolic me
Externí odkaz:
https://doaj.org/article/c95e793261f1414fa012ff25bc121064
Publikováno v:
Cancer Management and Research, Vol Volume 16, Pp 137-150 (2024)
Lvwen Ning,1,2 Ni Xie1 1Biobank, Shenzhen Second People’s Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen University, Shenzhen, People’s Republic of China; 2Shenzhen Institute of Advanced Technology, Chinese Academy of Scienc
Externí odkaz:
https://doaj.org/article/be32e430ce2a48a08bbaa3642b54e9ab
Autor:
Yue-Yue Guo, Nan-Nan Liang, Xiao-Yi Zhang, Ya-Hui Ren, Wen-Zheng Wu, Zhi-Bing Liu, Yi-Zhang He, Yi-Hao Zhang, Yi-Chao Huang, Tao Zhang, De-Xiang Xu, Shen Xu
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103179- (2024)
Increasing evidences demonstrate that environmental stressors are important inducers of acute kidney injury (AKI). This study aimed to investigate the impact of exposure to Cd, an environmental stressor, on renal cell ferroptosis. Transcriptomics ana
Externí odkaz:
https://doaj.org/article/6f33516360ad49fea8fd4d792998c314
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116689- (2024)
Ischemic heart disease invariably leads to devastating damage to human health. Nicotinamide ribose (NR), as one of the precursors of NAD+ synthesis, has been discovered to exert a protective role in various neurological and cardiovascular disorders.
Externí odkaz:
https://doaj.org/article/fe699c37aba6406bbd2ef4b77ac3cdad
Autor:
Elham Shoghi, Tahereh Safari, Abolfazl Parsi-Moud, Ilia Mirzaei, Nahid Sepehri Rad, Mohadeseh Chahkandi
Publikováno v:
Experimental Gerontology, Vol 191, Iss , Pp 112442- (2024)
In this study we investigated the potential synergistic effects of moderate interval training (MIT) and lithium on spatial learning and memory. Forty-two male Wistar males were classified into six groups including I: Control, II: 10 mg/kg/day IP lith
Externí odkaz:
https://doaj.org/article/f13b370a15a14856967d21f537012bd1
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e30568- (2024)
Autophagy during myocardial ischemia/reperfusion (MI/R) exacerbates cardiomyocyte injury. Melatonin (Mel) alleviates myocardial damage by regulating mitochondrial function and mitophagy, but the role of mitophagy in melatonin-induced cardioprotection
Externí odkaz:
https://doaj.org/article/c1f4d0bca69c4a839f10de657f860f6e
Autor:
Xin Han, Yan Ning, Xinyue Dou, Yiwen Wang, Qiyuan Shan, Kao Shi, Zeping Wang, Chuan Ding, Min Hao, Kuilong Wang, Mengyun Peng, Haodan Kuang, Qiao Yang, Xianan Sang, Gang Cao
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 5, Pp 100927- (2024)
Cornus officinalis, a medicinal and edible plant known for its liver-nourishing properties, has shown promise in inhibiting the activation of hepatic stellate cells (HSCs), crucial indicators of hepatic fibrosis, especially when processed by high pre
Externí odkaz:
https://doaj.org/article/677f5ec694494bd496abf24f3dc8b474