Zobrazeno 1 - 10
of 170
pro vyhledávání: '"sirna therapeutics"'
Autor:
Peng Chen, Zhihui Wang, Xinmo Wang, Junni Gong, Ju Sheng, Yufei Pan, Dandan Zhu, Xiaoxuan Liu
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 936 (2024)
Small interfering RNA (siRNA) therapeutics, characterized by high specificity, potency, and durability, hold great promise in the treatment of cancer and other diseases. However, the clinic implementation of siRNA therapeutics critically depends on t
Externí odkaz:
https://doaj.org/article/b8a208483bae46339eaff35668e9fd72
Akademický článek
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Autor:
Sarah M. Davis, Vignesh N. Hariharan, Agnes Lo, Anton A. Turanov, Dimas Echeverria, Jacquelyn Sousa, Nicholas McHugh, Annabelle Biscans, Julia F. Alterman, S. Ananth Karumanchi, Melissa J. Moore, Anastasia Khvorova
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 135-149 (2022)
Preeclampsia (PE) is a rising, potentially lethal complication of pregnancy. PE is driven primarily by the overexpression of placental soluble fms-like tyrosine kinase 1 (sFLT1), a validated diagnostic and prognostic marker of the disease when normal
Externí odkaz:
https://doaj.org/article/9a70cf9e7c9f406b9efc376a07ec4325
Autor:
Margaret Wallen, Farrukh Aqil, Raghuram Kandimalla, Jeyaprakash Jeyabalan, Supipi Auwardt, Neha Tyagi, David J. Schultz, Wendy Spencer, Ramesh C. Gupta
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 691-704 (2022)
Emerging viral diseases, such as Ebola, SARS, MERS, and the pathogen causing COVID-19, SARS-CoV-2, present a challenge for the development of therapeutics because of strict biosafety handling procedures and rapid mutation of their genomes. To facilit
Externí odkaz:
https://doaj.org/article/0ca6fe1b86d6456f92a34e2b76168ab7
Publikováno v:
International Journal of General Medicine, Vol Volume 15, Pp 5133-5144 (2022)
Haseena Sait, Somya Srivastava, Deepti Saxena Department of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, IndiaCorrespondence: Deepti Saxena, Department of Medical Genetics, Sanjay Gandhi Postgrad
Externí odkaz:
https://doaj.org/article/8b7836f8df1e424581e82de44f1e375c
Autor:
Daniyah A Almarghalani, Sai H.S. Boddu, Mohammad Ali, Akhila Kondaka, Devin Ta, Rayyan A Shah, Zahoor A Shah
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 8, Pp 1717-1725 (2022)
Intracerebral hemorrhage (ICH) is a subtype of stroke associated with higher rates of mortality. Currently, no effective drug treatment is available for ICH. The molecular pathways following ICH are complicated and diverse. Nucleic acid therapeutics
Externí odkaz:
https://doaj.org/article/135c8707d4434edb98498d9091f21a97
Autor:
Arpita Paul, Anuraag Muralidharan, Avirup Biswas, B Venkatesh Kamath, Alex Joseph, Angel Treasa Alex
Publikováno v:
OpenNano, Vol 7, Iss , Pp 100063- (2022)
Small interfering RNA (siRNA) has emerged as a promising strategy for treating several “undruggable” genetically impaired conditions. The siRNA-based drugs have opened the doors to a novel mode of therapy. Though siRNA is a potential therapeutic
Externí odkaz:
https://doaj.org/article/e05820d1879247b1837cb04614a60545
Autor:
Marija Buljan, Peter Wick
Publikováno v:
CHIMIA, Vol 76, Iss 3 (2022)
Nanomedicine encompasses usage of materials smaller than 100 nm for diagnosis, monitoring and treatment of disease. A frequent application of these materials is in reformulation of active drugs, which were previously approved for clinical use. As ill
Externí odkaz:
https://doaj.org/article/2d1c0094a2ce4b45b120503709439a1c
Akademický článek
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Akademický článek
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