Zobrazeno 1 - 10
of 676
pro vyhledávání: '"sinusoidal endothelial cell"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Liver fibrosis is a common progressive liver disease that can cause liver dysfunction and lead to serious complications. Zi Qi decoction (ZQ) is a traditional formulation that exerts pharmacological effects on the treatment of liver fibrosis
Externí odkaz:
https://doaj.org/article/dd4cf61ef741420a9a9674a801b1da82
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 4, Pp 1002-1004 (2024)
Externí odkaz:
https://doaj.org/article/41df6f043ee34e08a360a8ab55c2ffd0
Autor:
Sabin Bhandari, Ingelin Kyrrestad, Jaione Simón-Santamaría, Ruomei Li, Karolina Joanna Szafranska, Gianina Dumitriu, Javier Sánchez Romano, Bård Smedsrød, Karen Kristine Sørensen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Liver sinusoidal endothelial cells (LSECs) which make up the fenestrated wall of the hepatic sinusoids, are active scavenger cells involved in blood waste clearance and liver immune functions. Dexamethasone is a synthetic glucocorticoid commonly used
Externí odkaz:
https://doaj.org/article/ab75d3afdc8f40b7aff9ae5b89cda46b
Autor:
Miho Kurokawa, Takeshi Goya, Motoyuki Kohjima, Masatake Tanaka, Sadahiro Iwabuchi, Shigeyuki Shichino, Satoshi Ueha, Tomonobu Hioki, Tomomi Aoyagi, Motoi Takahashi, Koji Imoto, Shigeki Tashiro, Hideo Suzuki, Masaki Kato, Shinichi Hashimoto, Hideo Matsuda, Kouji Matsushima, Yoshihiro Ogawa
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Acute liver failure (ALF) is a life-threatening disorder that progresses from self-limiting acute liver injury (ALI). Microcirculatory disturbance characterized by sinusoidal hypercoagulation and subsequent massive hypoxic hepatoc
Externí odkaz:
https://doaj.org/article/f24b7de720914341bdd83383c484cd32
Publikováno v:
Materials & Design, Vol 245, Iss , Pp 113242- (2024)
Liver sinusoidal endothelial cells (LSECs) are the predominant endothelial cells (ECs) and the most abundant type of non-parenchymal cells (NPCs) in the liver, lining the low-shear sinusoidal channels. LSECs are not only a physical barrier but play m
Externí odkaz:
https://doaj.org/article/0ba5ee88238549b0ae1598f207596183
Publikováno v:
Waike lilun yu shijian, Vol 29, Iss 02, Pp 126-131 (2024)
The liver is the most common site of metastasis in patients with colorectal cancer(CRC). The liver microenvironment is a diverse assemblage of cells, which has their own unique biological characteristics and functions, supplemented by the interaction
Externí odkaz:
https://doaj.org/article/a222f7371f7d411191d467babd27b87b
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Aim To understand how liver sinusoidal endothelial cells (LSECs) respond to nonalcoholic steatohepatitis (NASH). Methods We profiled single-LSEC from livers of control and MCD-fed mice. The functions of C-Kit +-LSECs were determined using co
Externí odkaz:
https://doaj.org/article/6b318f011ecf4104bf823099b5ed0b20
Autor:
Bin Zuo, Fei Yang, Lulu Huang, Jingjing Han, Tianyi Li, Zhenni Ma, Lijuan Cao, Yun Li, Xia Bai, Miao Jiang, Yang He, Lijun Xia
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 1039-1061 (2024)
Background & Aims: The functional maturation of the liver largely occurs after birth. In the early stages of life, the liver of a newborn encounters enormous high-fat metabolic stress caused by the consumption of breast milk. It is unclear how the ma
Externí odkaz:
https://doaj.org/article/51d9ec5aad254259ba918fd9af186d61
Publikováno v:
Biomolecules & Biomedicine (2024)
Liver fibrosis, a common characteristic in various chronic liver diseases, is largely influenced by glycolysis. Quercetin (QE), a natural flavonoid known to regulate glycolysis, was studied for its effects on liver fibrosis and its underlying mechani
Externí odkaz:
https://doaj.org/article/2bdb9fec2bc1427e84378d53539b951c
Autor:
Fahong Li, Yingying Deng, Shenyan Zhang, Beidi Zhu, Jun Wang, Jinyu Wang, Xueyu Wang, Zhenyu Zhao, Wanyu Deng, Richeng Mao, Zhongliang Shen, Jieliang Chen, Ruth Broering, Yong Lin, Mengji Lu, Jiming Zhang
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 616-628 (2022)
Previous studies have revealed multiple tissue- or cell-specific or enriched miRNA profiles. However, miRNA profiles enriched in hepatic cell types and their effect on HBV replication have not been well elucidated. In this study, primary human hepato
Externí odkaz:
https://doaj.org/article/bb756a15c4c24a78b9a5fd74f46a8ab5