Zobrazeno 1 - 10
of 116
pro vyhledávání: '"sinoatrial node dysfunction"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Ca2+ plays a crucial role in excitation-contraction coupling in cardiac myocytes. Dysfunctional Ca2+ regulation alters the force of contraction and causes cardiac arrhythmias. Ca2+ entry into cardiomyocytes is mediated mainly through L-type Ca2+ chan
Externí odkaz:
https://doaj.org/article/c180319c150d4cccb4c3d49f92c89e07
Autor:
Susanne Rinné, Birgit Stallmeyer, Alexandra Pinggera, Michael F. Netter, Lina A. Matschke, Sven Dittmann, Uwe Kirchhefer, Ulrich Neudorf, Joachim Opp, Jörg Striessnig, Niels Decher, Eric Schulze-Bahr
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14215 (2022)
Cav1.3 voltage-gated L-type calcium channels (LTCCs) are involved in cardiac pacemaking, hearing and hormone secretion, but are also expressed postsynaptically in neurons. So far, homozygous loss of function mutations in CACNA1D encoding the Cav1.3
Externí odkaz:
https://doaj.org/article/21ab2a7f017542a4a07391735ba00caa
Autor:
Weijie Chen, Zengzhang Liu, Peilin Xiao, Yanping Xu, Dan Li, Qingsong Xiong, Lili Zou, Fang Qin, Xiexin Tao, Junan Chen, Xianbin Lan, Huaan Du, Yuehui Yin, Zhiyu Ling
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 9, Iss 6, p 188 (2022)
Cardioneuroablation (CNA) is proposed as a promising therapy for patients with sinoatrial node dysfunction (SND) that is mediated by excessive vagal tone. However, a series of urgent questions about CNA remain unanswered. From December 2020 to March
Externí odkaz:
https://doaj.org/article/ae6fa29b7717405faff4ec23d1bb72ee
Autor:
Michael J. Wallace, Mona El Refaey, Pietro Mesirca, Thomas J. Hund, Matteo E. Mangoni, Peter J. Mohler
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The pacemaker cells of the cardiac sinoatrial node (SAN) are essential for normal cardiac automaticity. Dysfunction in cardiac pacemaking results in human sinoatrial node dysfunction (SND). SND more generally occurs in the elderly population and is a
Externí odkaz:
https://doaj.org/article/12565219d0e44d409486f3ab9e98b4b4
Autor:
Lu Ren, Raghavender R. Gopireddy, Guy Perkins, Hao Zhang, Valeriy Timofeyev, Yankun Lyu, Daphne A. Diloretto, Pauline Trinh, Padmini Sirish, James L. Overton, Wilson Xu, Nathan Grainger, Yang K. Xiang, Elena N. Dedkova, Xiao-Dong Zhang, Ebenezer N. Yamoah, Manuel F. Navedo, Phung N. Thai, Nipavan Chiamvimonvat
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 36
The sinoatrial node (SAN), the leading pacemaker region, generates electrical impulses that propagate throughout the heart. SAN dysfunction with bradyarrhythmia is well documented in heart failure (HF). However, the underlying mechanisms are not comp
Publikováno v:
JACC: CardioOncology
Central Illustration
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3224 (2019)
Heart failure (HF) frequently coexists with atrial fibrillation (AF) and dysfunction of the sinoatrial node (SAN), the natural pacemaker. HF is associated with chronic adrenergic stimulation, neurohormonal activation, abnormal intracellular calcium h
Externí odkaz:
https://doaj.org/article/340c657bec9c4feb8a68b570e7f6336d
Publikováno v:
Cureus
Lithium is a common mood-stabilizing drug for manic patients. We describe a case of sinoatrial node dysfunction in a patient with serum lithium levels within the therapeutic range. Given the symptomology and severity of the patient’s illness, after
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Akademický článek
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