Zobrazeno 1 - 10
of 112
pro vyhledávání: '"single-cell transcriptome analysis"'
Autor:
Kevin W. Southerland, Yueyuan Xu, Derek T. Peters, Xin Lin, Xiaolin Wei, Yu Xiang, Kaileen Fei, Lindsey A. Olivere, Jeremy M. Morowitz, James Otto, Qunsheng Dai, Christopher D. Kontos, Yarui Diao
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-20 (2023)
Abstract Background Chronic limb-threatening ischemia (CLTI), a severe manifestation of peripheral arterial disease (PAD), is associated with a 1-year limb amputation rate of approximately 15–20% and substantial mortality. A key feature of CLTI is
Externí odkaz:
https://doaj.org/article/d8791787c9d54c2aab08d00540e6d0a0
Publikováno v:
Plants, Vol 13, Iss 9, p 1276 (2024)
Deep learning has emerged as a powerful tool for investigating intricate biological processes in plants by harnessing the potential of large-scale data. Gene regulation is a complex process that transcription factors (TFs), cooperating with their tar
Externí odkaz:
https://doaj.org/article/60e0be67dfb94f3d84d038823867bc76
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background and objectives Phenotypic switching in vascular smooth muscle cells (VSMCs) has been linked to aortic aneurysm, but the phenotypic landscape in aortic aneurysm is poorly understood. The present study aimed to analyse the phenotypi
Externí odkaz:
https://doaj.org/article/8ecbe3ec9baa419fa715a0b10402e1ac
Autor:
Jian Wang, Hong-Cun Sun, Cheng Cao, Jian-Dao Hu, Jing Qian, Tao Jiang, Wen-Bo Jiang, Shao Zhou, Xiao-Wen Qiu, Hong-Li Wang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe heterogeneous crosstalk between tumor cells and other cells in their microenvironment means a notable difference in clinical outcomes of head and neck squamous cell carcinoma (HNSCC). CD8+ T cells and macrophages are effector factors of
Externí odkaz:
https://doaj.org/article/a8ef09eb9b294069942c0855a5159842
Publikováno v:
Molecules, Vol 28, Iss 23, p 7704 (2023)
Due to the narrow therapeutic window and high mortality of ischemic stroke, it is of great significance to investigate its diagnosis and therapy. We employed weighted gene coexpression network analysis (WGCNA) to ascertain gene modules related to str
Externí odkaz:
https://doaj.org/article/13d4aa07b95147529d002a6e30e006bf
Akademický článek
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Akademický článek
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Publikováno v:
Xin yixue, Vol 53, Iss 4, Pp 292-296 (2022)
Objective To reveal the change trajectory of T lymphocytes in the dialysis effluent from peritoneal dialysis (PD) patients with the prolongation of PD time, and to explore its relationship with PD-associated peritoneal fibrosis. Methods Cell clas
Externí odkaz:
https://doaj.org/article/f56b771eec3547c88780e29b204ba54e
Autor:
Shiyong Wu, Shibiao Liu, Baoheng Wang, Meng Li, Chao Cheng, Hairong Zhang, Ningheng Chen, Xueli Guo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
Abdominal aortic aneurysm (AAA) is a life-threatening disease and there is currently a lack of effective treatment to prevent it rupturing. ScRNA-seq studies of AAA are still lacking. In the study, we analyzed the published AAA scRNA-seq datasets fro
Externí odkaz:
https://doaj.org/article/b6af65ce80d34c7db5bcfcf992e26bda
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Aging is characterized by the gradual loss of physiological integrity, resulting in impaired function and easier death. This deterioration is a major risk factor for major human pathological diseases, including cancer, diabetes, cardiovas
Externí odkaz:
https://doaj.org/article/b5aaef77dc0f40579ab064006c098847