Zobrazeno 1 - 10
of 318
pro vyhledávání: '"single strand DNA-binding protein"'
Autor:
Xian Wang, Yuetong Wang, Xianglin Zeng, Haoyu Lu, Dongqin Mo, Yuetao Li, Zhiqing Liu, Yude Huang, Kun Yu, Daiyou Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesSingle-strand DNA-binding protein 1 (SSB1) plays a crucial role in the cellular response to DNA damage. This study aimed to explore the expression and regulation of SSB1 in normal rat salivary gland tissues and tissues following radiation,
Externí odkaz:
https://doaj.org/article/e1ebd6b7ccac43a48314924fffce27b5
Autor:
Jian-jie Gao, Ri-he Peng, Bo Zhu, Yong-sheng Tian, Jing Xu, Bo Wang, Xiao-yan Fu, Hong-juan Han, Li-juan Wang, Fu-jian Zhang, Wen-hui Zhang, Yong-dong Deng, Yu- Wang, Zhen-Jun Li, Quan-Hong Yao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 220, Iss , Pp 112407- (2021)
2,4,6-trinitrotoluene (TNT) and cobalt (Co) contaminants have posed a severe environmental problem in many countries. Phytoremediation is an environmentally friendly technology for the remediation of these contaminants. However, the toxicity of TNT a
Externí odkaz:
https://doaj.org/article/8174a5ad8b54401f85f6c1e8e3eb2f53
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Accurate DNA replication is essential for maintaining genome stability. However, this stability becomes vulnerable when replication fork progression is stalled or slowed – a condition known as replication stress. Prolonged fork stalling can cause D
Externí odkaz:
https://doaj.org/article/1f094f61c71c492fabee3f6ef845cc36
Akademický článek
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Akademický článek
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Autor:
Teisuke Takita, Kaichi Hayashi, Kiyoshi Yasukawa, Shihomi Akagi, Kevin Maafu Juma, Kenji Kojima, Shinsuke Fujiwara, Ciara K. O'Sullivan, Itaru Yanagihara, Yukiko Nakura
Publikováno v:
Journal of Bioscience and Bioengineering. 131:219-224
Recombinase polymerase amplification (RPA) is a technique that is used to specifically amplify a target nucleic acid sequence. Unlike the polymerase chain reaction (PCR), RPA is performed at a constant temperature between 37 and 42°C. Therefore, it
Publikováno v:
eLife, Vol 5 (2016)
The resection of DNA strand with a 5´ end at double-strand breaks is an essential step in recombinational DNA repair. RecJ, a member of DHH family proteins, is the only 5´ nuclease involved in the RecF recombination pathway. Here, we report the cry
Externí odkaz:
https://doaj.org/article/9eb70f6daebe43b79451f1a70609e1ae
Autor:
Shinsuke Fujiwara, Kevin Maafu Juma, Kiyoshi Yasukawa, Shihomi Akagi, Manish Biyani, Yukiko Nakura, Itaru Yanagihara, Kenji Ito, Emi Arikawa, Masaya Yamagata, Teisuke Takita, Kenji Kojima
Publikováno v:
Biochemical and Biophysical Research Communications
Recombinase polymerase amplification (RPA) is an isothermal reaction that amplifies a target DNA sequence with a recombinase, a single-stranded DNA-binding protein (SSB), and a strand-displacing DNA polymerase. In this study, we optimized the reactio
Autor:
Tatos Akopian, Junhao Zhu, Michael R. Chase, Olga Kandror, Jemila C. Kester, Alfred L. Goldberg, Eric J. Rubin, Sarah M. Fortune
Publikováno v:
Journal of Bacteriology
Tuberculosis, caused by Mycobacterium tuberculosis, imposes a major global health burden, surpassing HIV and malaria in annual deaths. The ClpP1P2 proteolytic complex and its cofactor ClpX are attractive drug targets, but their precise cellular funct
Autor:
Jing Xu, Ri-He Peng, Quan-Hong Yao, Wang Lijuan, Deng Yongdong, Li Zhenjun, Han Hongjuan, Zhang Fujian, Fu Xiaoyan, Zhang Wenhui, Bo Zhu, Yu Wang, Gao Jianjie, Tian Yongsheng, Bo Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 220, Iss, Pp 112407-(2021)
2,4,6-trinitrotoluene (TNT) and cobalt (Co) contaminants have posed a severe environmental problem in many countries. Phytoremediation is an environmentally friendly technology for the remediation of these contaminants. However, the toxicity of TNT a