Výsledky vyhledávání - "single drug dose"

Pregabalin Ameliorates Lipopolysaccharide-Induced Pancreatic Inflammation in Aged Rats

Autor: Ozlem Ozmen, Senay Topsakal

Publikováno v: Endocrine, Metabolic & Immune Disorders - Drug Targets. 19:1141-1147

Objective: The aim of this study was to examine pancreatic pathology and the prophylactic effects of pregabalin in lipopolysaccharide (LPS) induced sepsis model in aged rats. Methods: Twenty-four female, one-year-old, Wistar Albino rats were assigned

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f9114be52657faf470b2e0452280f8
https://doi.org/10.2174/1871530319666190306095532

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Efeito protetor do ácido gálico contra a ototoxicidade induzida por cisplatina em ratos

Autor: Seda Askin, Fazile Nur Ekinci Akdemir, Yavuz Selim Saglam, Muhammed Sedat Sakat, Korhan Kilic, Serkan Yildirim

Publikováno v: Brazilian Journal of Otorhinolaryngology, Vol 85, Iss 3, Pp 267-274 (2019)
Brazilian Journal of Otorhinolaryngology v.85 n.3 2019
Brazilian Journal of Otorhinolaryngology
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF

Introduction: Cisplatin is an antineoplastic agent widely used in the treatment of a variety of cancers. Ototoxicity is one of the main side-effects restricting the use of cisplatin. Objective: The purpose of this study was to investigate the protect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848ef76cea05fd0eed8b50e564c2016a
http://www.sciencedirect.com/science/article/pii/S1808869418300880

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Recruitment of macrophages and bone marrow stem cells to regenerating liver promoted by sodium phthalhydrazide in mice

Autor: Irina A. Kazakova, Boris G. Yushkov, Irina G. Danilova, Anna V. Belousova, Artem S. Minin, Musa T. Abidov

Publikováno v: Biomedicine and Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 110, Iss, Pp 594-601 (2019)

Pharmacological interventions which could be hepatoprotective, depending on bioavailability, anti-inflammatory and macrophage-targeting potential of drugs, are still at early preclinical stages. Existing evidence from many animal models of liver inju

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62004ce2a8dde201baab9995b4a28de8
https://doi.org/10.1016/j.biopha.2018.07.086

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Single-Dose Tafenoquine to Prevent Relapse ofPlasmodium vivaxMalaria

Publikováno v: The New England Journal of Medicine

Background Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed “radical cure”). Tafenoquine is a single-dose 8-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d64bc83a97e78715cfe8f83b368a046
https://doi.org/10.1056/nejmoa1710775

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Prognostic significance of primary tumor localization in patients with metastatic colorectal cancer: Is it beneficial to select targeted treatment? Real-life experience from Turkey

Autor: Cakan B., Acikgoz O., Bilici A., Demir T., Oven B.B., Hamdard J., Olmuscelik O.

Purpose: The purpose of this study was to investigate the prognostic value,and the effect of primary tumor location on targeted therapy selection in patients with metastatic colorectal cancer (mCRC). Methods: A total of 201 patients with de novo mCRC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10652::269fa61bb8d768962d9780934282df69
https://hdl.handle.net/11499/47912

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Tocilizumab in COVID-19: Enthusiasm vs. evidence

Autor: Paola Zena-Huancas, Mayte Bryce-Alberti, Arianna Portmann-Baracco, Franco Leon-Jimenez

Publikováno v: Lung India : Official Organ of Indian Chest Society

Based on the pathophysiological characterization of COVID-19, initial studies suggested the use of tocilizumab (TCZ), a recombinant humanized monoclonal antibody of the immunoglobulin G1 class, for management of the cytokine storm witnessed in severe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63ecf8e6649992af363694b426c47f3
https://hdl.handle.net/20.500.12866/10191

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Preventive effect of agomelatine in lipopolysaccharide-induced pancreatic pathology

Autor: Senay Topsakal, Ozlem Ozmen

The aim of this study was to examine pancreatic lesions and the possible prophylactic effects of agomelatine (AGO) in lipopolysaccharide (LPS)-induced sepsis in rats. Twenty-four female, 1-year-old Wistar albino rats were divided into three groups: g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dac94f757531c1ddcaa1806e981e75f
https://doi.org/10.1080/01480545.2019.1675686

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