Zobrazeno 1 - 2
of 2
pro vyhledávání: '"single cell RNA/ATAC-seq"'
Autor:
Allen Wang, Joshua Chiou, Olivier B Poirion, Justin Buchanan, Michael J Valdez, Jamie M Verheyden, Xiaomeng Hou, Parul Kudtarkar, Sharvari Narendra, Jacklyn M Newsome, Minzhe Guo, Dina A Faddah, Kai Zhang, Randee E Young, Justinn Barr, Eniko Sajti, Ravi Misra, Heidie Huyck, Lisa Rogers, Cory Poole, Jeffery A Whitsett, Gloria Pryhuber, Yan Xu, Kyle J Gaulton, Sebastian Preissl, Xin Sun, NHLBI LungMap Consortium
Publikováno v:
eLife, Vol 9 (2020)
Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we present single-nucleus accessible chromatin profiles of 90,980 nuclei and matched single-nucleus transcriptomes of 46,500 nuclei in non-diseased lungs from donors of
Externí odkaz:
https://doaj.org/article/a3ede76a7aec424cbe10045fed11ea98
Autor:
Wang A; Center for Epigenomics & Department of Cellular & Molecular Medicine, University of California, San Diego, San Diego, United States., Chiou J; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, United States.; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Poirion OB; Center for Epigenomics & Department of Cellular & Molecular Medicine, University of California, San Diego, San Diego, United States., Buchanan J; Center for Epigenomics & Department of Cellular & Molecular Medicine, University of California, San Diego, San Diego, United States., Valdez MJ; Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, United States.; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Verheyden JM; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Hou X; Center for Epigenomics & Department of Cellular & Molecular Medicine, University of California, San Diego, San Diego, United States., Kudtarkar P; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Narendra S; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Newsome JM; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Guo M; Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.; Divisions of Pulmonary Biology and Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, United States., Faddah DA; Vertex Pharmaceuticals, San Diego, United States., Zhang K; Ludwig Institute for Cancer Research, La Jolla, United States., Young RE; Department of Pediatrics, University of California-San Diego, La Jolla, United States.; Laboratory of Genetics, Department of Medical Genetics, University of Wisconsin-Madison, Madison, United States., Barr J; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Sajti E; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Misra R; Department of Pediatrics and Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, United States., Huyck H; Department of Pediatrics and Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, United States., Rogers L; Department of Pediatrics and Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, United States., Poole C; Department of Pediatrics and Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, United States., Whitsett JA; Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.; Divisions of Pulmonary Biology and Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, United States., Pryhuber G; Department of Pediatrics and Clinical & Translational Science Institute, University of Rochester Medical Center, Rochester, United States., Xu Y; Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, United States.; Divisions of Pulmonary Biology and Biomedical Informatics, University of Cincinnati College of Medicine, Cincinnati, United States., Gaulton KJ; Department of Pediatrics, University of California-San Diego, La Jolla, United States., Preissl S; Center for Epigenomics & Department of Cellular & Molecular Medicine, University of California, San Diego, San Diego, United States., Sun X; Department of Pediatrics, University of California-San Diego, La Jolla, United States.; Department of Biological Sciences, University of California-San Diego, La Jolla, United States.
Publikováno v:
ELife [Elife] 2020 Nov 09; Vol. 9. Date of Electronic Publication: 2020 Nov 09.