Zobrazeno 1 - 10
of 89
pro vyhledávání: '"single‐nucleus sequencing"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Archived samples, including frozen and formalin fixed paraffin embedded (FFPE) tissues, are a vast resource of clinically annotated materials for the application of high-definition genomics to improve patient management and provid
Externí odkaz:
https://doaj.org/article/9e9a057fd7994f9285c1bfaa2a32a317
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract The cell and molecular bases of arbuscular mycorrhizal (AM) symbiosis, a crucial plant-fungal interaction for nutrient acquisition, have been extensively investigated by coupling traditional RNA sequencing techniques of roots sampled in bulk
Externí odkaz:
https://doaj.org/article/9097e548b42e4e65a88f0b797e9ead89
Autor:
Yingying Liu, Yinchao Li, Yaqian Zhang, Yubao Fang, Lei Lei, Jiabin Yu, Hongping Tan, Lisen Sui, Qiang Guo, Liemin Zhou
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background Focal cortical dysplasia (FCD) is a heterogeneous group of cortical developmental malformations that constitute a common cause of medically intractable epilepsy. FCD type IIIa (FCD IIIa) refers to temporal neocortex alterations in
Externí odkaz:
https://doaj.org/article/c2ed1bfee16549cda969c7e882e9a5b6
Autor:
Jieqiong Xie, Yating Lan, Cuihua Zou, Jingfeng He, Qi Huang, Jingyi Zeng, Mika Pan, Yujia Mei, Jiefeng Luo, Donghua Zou
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Alzheimer’s disease (AD) is a complicated neurodegenerative disease. Neuron-glial cell interactions are an important but not fully understood process in the progression of AD. We used bioinformatic methods to analyze single-nucl
Externí odkaz:
https://doaj.org/article/a646a52ec5c94781922b8fa64a7f8b7f
Autor:
Mingxi Hou, Jin Zhang, Qi Wang, Ran Zhao, Yiming Cao, Yingjie Chen, Kaikuo Wang, Ning Ding, Yingjie Qi, Xiaoqing Sun, Yan Zhang, Jiongtang Li
Publikováno v:
Animals, Vol 14, Iss 22, p 3263 (2024)
The common carp (Cyprinus carpio) is a crucial freshwater species cultivated worldwide for food consumption. Female carp have better growth performance than males, which fascinates scholars to uncover the mechanism of gonadal differentiation and prod
Externí odkaz:
https://doaj.org/article/5a1569c9777546e9a3c6d0cf0fbbded1
Autor:
Qing Liu, Ziyu Liu, Wenmeng Xie, Yibo Li, Hongfang Wang, Sanbing Zhang, Wenyu Wang, Jiaxin Hao, Dandan Geng, Jing Yang, Lei Wang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundN-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin widely used to induce PD models, but the effect of MPTP on the cells and genes of PD has not been fully elucidated.MethodsSingle-nucleus RNA sequencing was performed in the
Externí odkaz:
https://doaj.org/article/c55e73229df544468bdfb956be58dd5e
Publikováno v:
Medicine Advances, Vol 1, Iss 3, Pp 234-245 (2023)
Abstract Background The plasticity of endothelial cells (ECs) is crucial for tissue response to injury. Myocardial infarction can profoundly affect EC function, leading to a shift toward mesenchymal differentiation. Methods We utilized human single
Externí odkaz:
https://doaj.org/article/7caedd7f580c4931809d4ebdb55a5630
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e26803- (2024)
Aims: Dilated cardiomyopathy refers to a heart muscle condition characterized by structural and functional irregularities in the myocardium that are not related to ischemia. Due to diverse etiologies such as genetic mutations, infections, and exposur
Externí odkaz:
https://doaj.org/article/2ad6884794964fd7a384fa9351cc746c
Autor:
Jelle van Creij, Ben Auxier, Jianyong An, Raúl Y. Wijfjes, Claudia Bergin, Anna Rosling, Ton Bisseling, Zhiyong Pan, Erik Limpens
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background Arbuscular mycorrhizal (AM) fungi are arguably the most important symbionts of plants, offering a range of benefits to their hosts. However, the provisioning of these benefits does not appear to be uniform among AM fungal individu
Externí odkaz:
https://doaj.org/article/0db0a4db865a4c03a43bebfd792d0996
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