Zobrazeno 1 - 10
of 3 609
pro vyhledávání: '"signal transducer and activator of transcription 3"'
Publikováno v:
Shipin Kexue, Vol 45, Iss 18, Pp 242-249 (2024)
Signal transducer and activator of transcription 3 (STAT3) exists in the cytoplasm, nucleus, mitochondria, and mitochondria associated endoplasmic reticulum membranes, which is a signal transduction protein involved in various physiological processes
Externí odkaz:
https://doaj.org/article/66f49ffa9911468dbba5f57e28c9e071
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Zinc finger protein 263 (ZNF263) is frequently upregulated in various tumor types; however, its function and regulatory mechanism in colorectal cancer (CRC) have not yet been elucidated. In this study, the expression of ZNF263 was systematic
Externí odkaz:
https://doaj.org/article/5132638c12d14047bd40a37c24b5c3b7
Autor:
Hao Yuan, Ming Zhong, Jie Liu, Shuya Tang, Hongbo Zhu, Qingping Wei, Bingbing Pu, Yongping Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a protein that regulates apoptosis and programmed cell death. This research aims to evaluate its potential role in inhibiting breast cancer cell proliferation, migration, and glycolysis and
Externí odkaz:
https://doaj.org/article/552b122dcb354042b019bf6b3c423bf8
Autor:
Yi Li, Yuyan Dong
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cervical cancer (CC) is a significant global health concern, demanding the consideration of novel therapeutic strategies. The signal transducer and activator of transcription 3 (STAT3) pathway has been implicated in cancer progres
Externí odkaz:
https://doaj.org/article/da7566f9141f43cd8c39fbf94d22cef8
Autor:
Tianyu Zhai, Liang Cai, Xi Jia, Mingfeng Xia, Hua Bian, Xin Gao, Chenling Pan, Xiaoying Li, Pu Xia
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102026- (2024)
Objective: Non-alcoholic fatty liver disease (NAFLD) is deemed as an emerging global epidemic, whereas the underlying pathogenic mechanism remains to be clarified. We aimed to systemically analyze all the NAFLD-related gene expression datasets from p
Externí odkaz:
https://doaj.org/article/91171bfc258742e8b4ef26786224e827
Autor:
Yu Pan, Lin Zhang, Wenjie Ma, Yassein M. Ibrahim, Wenli Zhang, Mengjie Wang, Xinrong Wang, Yunfei Xu, Caixia Gao, Hongyan Chen, He Zhang, Changyou Xia, Yue Wang
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major thread to the global swine industry, lack of effective control strategies. This study explores the regulatory role of a small non-coding RNA, miR-191-5p, in PRRSV infection. We ob
Externí odkaz:
https://doaj.org/article/f1f759d71355455eaa36a42b30be43b5
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 12, Iss , Pp 100477- (2024)
Introduction: Malignant ascites is a common complication of advanced hepatocellular carcinoma (HCC) that seriously affects the quality of life and survival of patients and has poor clinical efficacy. In the early stages, the authors found that the co
Externí odkaz:
https://doaj.org/article/41af980b6f994589a9d24364cf885244
Autor:
Ting Li, Tongtong Pan, Nannan Zheng, Xiong Ma, Xiaodong Wang, Fang Yan, Huimian Jiang, Yuxin Wang, Hongwei Lin, Jing Lin, Huadong Zhang, Jia Huang, Lingming Kong, Anmin Huang, Qingxiu Liu, Yongping Chen, Dazhi Chen
Publikováno v:
Engineering, Vol 36, Iss , Pp 209-222 (2024)
One-third of patients with autoimmune hepatitis (AIH) have cirrhosis at the time of diagnosis. The relevance of these variables, although unknown, is believed to be critical in AIH because of suspected interactions between the gut microbiome and gene
Externí odkaz:
https://doaj.org/article/2853562ca98748e585065151cedaa1a0
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Aim To elucidate the biological functionality and regulatory mechanisms of GdX in breast cancer (BC).Methods The examination of GdX expression in human BC tissues and cell lines was conducted through immunohistochemical (IHC) and Western blot. Cell p
Externí odkaz:
https://doaj.org/article/5fc84c59aee149298ca996e54e0883dc
Autor:
Adil Karim, Rashi Garg, Biman Saikia, Abha Tiwari, Smrity Sahu, Mehak Malhotra, Ranjana W. Minz, Amit Rawat, Surjit Singh, Deepti Suri
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPatients with loss of function signal transducer and activator of transcription 3-related Hyper IgE Syndrome (LOF STAT3 HIES) present with recurrent staphylococcal skin and pulmonary infections along with the elevated serum IgE levels, ecze
Externí odkaz:
https://doaj.org/article/74133cf61e324bbfa36cdecfba5e5655