Zobrazeno 1 - 10
of 6 365
pro vyhledávání: '"signal transducer and activator of transcription"'
Autor:
Jeonghyeon Moon, Keun-Hyung Cho, JooYeon Jhun, JeongWon Choi, Hyun-Sik Na, Jeong Su Lee, Seung Yoon Lee, Jun-Ki Min, Anan Shetty, Sung-Hwan Park, Seok Jung Kim, Mi-La Cho
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Objective Osteoarthritis (OA) is a degenerative joint disease caused by the breakdown of joint cartilage and adjacent bone. Joint injury, being overweight, differences in leg length, high levels of joint stress, abnormal joint or limb develo
Externí odkaz:
https://doaj.org/article/918bd055aef54a63a6b69ed875df85ba
Publikováno v:
环境与职业医学, Vol 41, Iss 10, Pp 1167-1172 (2024)
BackgroundDi(2-ethylhexyl) phthalate (DEHP) is the highest consumed and the most widely used phthalic acid ester, their effects on lipid metabolism have attracted the attention of many scholars. However, the associated mechanism is still unclear.Obje
Externí odkaz:
https://doaj.org/article/96de5460983c41d596c3ca759479503e
Publikováno v:
Shipin Kexue, Vol 45, Iss 18, Pp 242-249 (2024)
Signal transducer and activator of transcription 3 (STAT3) exists in the cytoplasm, nucleus, mitochondria, and mitochondria associated endoplasmic reticulum membranes, which is a signal transduction protein involved in various physiological processes
Externí odkaz:
https://doaj.org/article/66f49ffa9911468dbba5f57e28c9e071
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Zinc finger protein 263 (ZNF263) is frequently upregulated in various tumor types; however, its function and regulatory mechanism in colorectal cancer (CRC) have not yet been elucidated. In this study, the expression of ZNF263 was systematic
Externí odkaz:
https://doaj.org/article/5132638c12d14047bd40a37c24b5c3b7
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1229-1235 (2024)
Objective To investigate the effect of scutellarin(STR) on the proliferation and migration of human prostate cancer cell line (PC-3) and its underlying mechanism. Methods PC-3 cells were divided into low-dose STR group, medium-dose STR group, high-do
Externí odkaz:
https://doaj.org/article/d5920e76b6e9452185e39d6da8044de0
Autor:
Hao Yuan, Ming Zhong, Jie Liu, Shuya Tang, Hongbo Zhu, Qingping Wei, Bingbing Pu, Yongping Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a protein that regulates apoptosis and programmed cell death. This research aims to evaluate its potential role in inhibiting breast cancer cell proliferation, migration, and glycolysis and
Externí odkaz:
https://doaj.org/article/552b122dcb354042b019bf6b3c423bf8
Autor:
Liping Guo, Dongli Lian, Yuchen Gu, Xiaoyu Lu, Ying Zhang, Xiaohe Li, Tatyana Aleksandrovna Khrustaleva, Jianfeng Lan, Yanhua Liang, Vladislav Victorovich Khrustalev, Yanyan Mao, Yafan Chen, Hongzhou Lu, Jing Yuan
Publikováno v:
hLife, Vol 2, Iss 8, Pp 397-418 (2024)
Inborn errors of the signal transducer and activator of transcription 1 (STAT1) result in four types of immunodeficiency disease with varying degrees of impaired STAT1 function: autosomal recessive (AR) complete STAT1 deficiency, AR partial STAT1 def
Externí odkaz:
https://doaj.org/article/86be93435871497f9276c4e2f263ba3b
Autor:
Yi Li, Yuyan Dong
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cervical cancer (CC) is a significant global health concern, demanding the consideration of novel therapeutic strategies. The signal transducer and activator of transcription 3 (STAT3) pathway has been implicated in cancer progres
Externí odkaz:
https://doaj.org/article/da7566f9141f43cd8c39fbf94d22cef8
Autor:
Shishi He, Guowei Huang, Rong Lei, Rurong Jia, Zhanghai He, Jiewen Chen, Hongyan Huang, Zixian Huang, Ailifeire Yilihamu, Xun Li, Zilin Zhuang, Mengjia Han, Xueman Chen, Di Huang, Yan Nie
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2942-2958 (2024)
Breast phyllodes tumor (PT) is a rare fibroepithelial neoplasm with potential malignant behavior. Long non-coding RNAs (lncRNAs) play multifaceted roles in various cancers, but their involvement in breast PT remains largely unexplored. In this study,
Externí odkaz:
https://doaj.org/article/5addf9582b1745519e43900146989196
Autor:
Tianyu Zhai, Liang Cai, Xi Jia, Mingfeng Xia, Hua Bian, Xin Gao, Chenling Pan, Xiaoying Li, Pu Xia
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102026- (2024)
Objective: Non-alcoholic fatty liver disease (NAFLD) is deemed as an emerging global epidemic, whereas the underlying pathogenic mechanism remains to be clarified. We aimed to systemically analyze all the NAFLD-related gene expression datasets from p
Externí odkaz:
https://doaj.org/article/91171bfc258742e8b4ef26786224e827