Zobrazeno 1 - 10
of 18
pro vyhledávání: '"siRNAs, Small interfering RNAs"'
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 340-354 (2021)
Acta Pharmaceutica Sinica B, Vol 11, Iss 2, Pp 340-354 (2021)
Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively participate in crucial physiological processes such as metabolism and immunity, and are closely related to the occurrence and development of tumors, cardiovascular dis
Autor:
Nabil Ahmed, Khaled Sanber, Mohamed Z. Gad, Ahmed Z. Gad, Hafez Mohamed Hafez, Amira Abdel Motaal, Rana Ahmed Youness, Emad Khallaf, Gi-Ja Lee, Yong Jin Ahn
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 27, Iss, Pp 177-190 (2021)
Journal of Advanced Research, Vol 27, Iss, Pp 177-190 (2021)
Graphical abstract
Introduction Hydrogen sulphide (H2S) has been established as a key member of the gasotransmitters family that recently showed a pivotal role in various pathological conditions including cancer. Objectives This study investigat
Introduction Hydrogen sulphide (H2S) has been established as a key member of the gasotransmitters family that recently showed a pivotal role in various pathological conditions including cancer. Objectives This study investigat
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 910-928 (2021)
Graphical abstract
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA molecules derived from exonic or intronic sequences by precursor mRNA back-splicing. Unlike canonical linear RNAs, circRNAs form covalently
Publikováno v:
International Immunopharmacology
SARS-CoV-2, as the causative agent of COVID-19, is an enveloped positives-sense single-stranded RNA virus that belongs to the Beta-CoVs sub-family. A sophisticated hyper-inflammatory reaction named cytokine storm is occurred in patients with severe/c
Akademický článek
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Publikováno v:
Redox Biology, Vol 45, Iss, Pp 102049-(2021)
Redox Biology
Redox Biology
Mitochondrial dysfunction is a fundamental challenge in septic cardiomyopathy. Mitophagy and the mitochondrial unfolded protein response (UPRmt) are the predominant stress-responsive and protective mechanisms involved in repairing damaged mitochondri
Autor:
Teng Yao, Jianle Wang, Yizhen Huang, Zizheng Chen, Yining Xu, Yute Yang, Pu-tao Yuan, Jianjun Ma, Shuying Shen, Jun Gao, Shasha Yao
Publikováno v:
The Journal of Biological Chemistry
Osteoporosis results from an imbalance between bone formation and bone resorption. Traditional drugs for treating osteoporosis are associated with serious side effects, and thus, new treatment methods are required. This study investigated the role of
Autor:
Yi Shi, Wenjuan Zhuang, Dake Zhang, Xiaotong Han, Changqing Zeng, Yingying Wen, Shiming Jiao, Fuxin Zhao, Tianzi Liu, Zhenglin Yang, Jia Qu, Yun Zhu, Fei Zhao, Mingguang He, Anquan Xue, Nethrajeith Srinivasalu, Wei Chen, Yingxiang Li, Yaqiang Hong, Yongchao Su, Qinkang Lu, Jing Tang, Jiaofeng Yan, Qiongsi Wang, Deng Wu, Guoyun Zhang, Lulin Huang, Qingyi Zhou, Ying Zhai, Xiangtian Zhou
Publikováno v:
EBioMedicine, Vol 57, Iss, Pp 102878-(2020)
EBioMedicine
EBioMedicine
Background Myopia is a good model for understanding the interaction between genetics and environmental stimuli. Here we dissect the biological processes affecting myopia progression. Methods Human Genetic Analyses: (1) gene set analysis (GSA) of new
Publikováno v:
Cell Calcium
Graphical abstract
The mitochondrial permeability transition pore (mPTP) has long been known to have a role in mitochondrial calcium (Ca2+) homeostasis under pathological conditions as a mediator of the mitochondrial permeability transition and
The mitochondrial permeability transition pore (mPTP) has long been known to have a role in mitochondrial calcium (Ca2+) homeostasis under pathological conditions as a mediator of the mitochondrial permeability transition and