Zobrazeno 1 - 10
of 28 505
pro vyhledávání: '"shp2"'
Publikováno v:
Journal of Gynecologic Oncology. Sep2024, Vol. 35 Issue 5, p1-17. 17p.
Autor:
Liu, Xibo1 (AUTHOR), Li, Mengyao1 (AUTHOR), Chen, Lirong2 (AUTHOR), Wen, Fei3 (AUTHOR), Zheng, Shu3 (AUTHOR), Ge, Weiting3 (AUTHOR)
Publikováno v:
Indian Journal of Pathology & Microbiology. Jan-Mar2024, Vol. 67 Issue 1, p29-35. 7p.
Autor:
Gao, Xiaobing1 (AUTHOR), Shao, Suhua1 (AUTHOR), Zhang, Xi2 (AUTHOR), Li, Changjie3 (AUTHOR), Jiang, Qianqian4 (AUTHOR) whdxrmyyjqq@163.com, Li, Bo1 (AUTHOR) kreuz-kreuz@163.com
Publikováno v:
PLoS ONE. 10/18/2024, Vol. 19 Issue 10, p1-24. 24p.
Autor:
Singh, Pooja1 (AUTHOR) poojaniper1410@gmail.com, Kumar, Vikas2 (AUTHOR) vikaspathania777@gmail.com, Lee, Keun Woo3,4 (AUTHOR) woo.lee@kqchub.com, Hong, Jong Chan1 (AUTHOR) woo.lee@kqchub.com
Publikováno v:
Pharmaceuticals (14248247). Jul2024, Vol. 17 Issue 7, p935. 19p.
Autor:
Abbasi, Mojdeh1,2 Mojdeh.abbasi@hdr.mq.edu.au, Gupta, Vivek1 vivek.gupta@mq.edu.au, Chitranshi, Nitin1, Moustardas, Petros2, Ranjbaran, Reza3, Graham, Stuart L.1
Publikováno v:
Aging & Disease. Oct2024, Vol. 15 Issue 5, p2051-2068. 18p.
Autor:
Michelangelo Marasco, John Kirkpatrick, Teresa Carlomagno, Jochen S. Hub, Massimiliano Anselmi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1169-1180 (2024)
SHP2 is a tyrosine phosphatase that plays a regulatory role in multiple intracellular signaling cascades and is known to be oncogenic in certain contexts. In the absence of effectors, SHP2 adopts an autoinhibited conformation with its N-SH2 domain bl
Externí odkaz:
https://doaj.org/article/0029acf72ec94573abd1f3e2e607cb5f
Autor:
Tojjari, Alireza1 (AUTHOR), Saeed, Anwaar1 (AUTHOR), Sadeghipour, Arezoo2 (AUTHOR), Kurzrock, Razelle3 (AUTHOR), Cavalcante, Ludimila4 (AUTHOR) ludi.cavalcante@gmail.com
Publikováno v:
Cancers. Nov2023, Vol. 15 Issue 22, p5384. 26p.
Akademický článek
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Autor:
Rehman, Ashfaq Ur1 (AUTHOR), Zhao, Cizhang1 (AUTHOR), Wu, Yongxian1 (AUTHOR) aurehman@uci.edu, Zhu, Qiang1 (AUTHOR), Luo, Ray1 (AUTHOR) rluo@uci.edu
Publikováno v:
International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p6201. 15p.
Autor:
Kai Tang, Shu Wang, Siqi Feng, Xinyu Yang, Yueyang Guo, Xiangli Ren, Linyue Bai, Bin Yu, Hong-Min Liu, Yihui Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3624-3642 (2024)
Src homology-2-containing protein tyrosine phosphatase 2 (SHP2) is a promising therapeutic target for cancer therapy. In this work, we presented the structure-guided design of 5,6-fused bicyclic allosteric SHP2 inhibitors, leading to the identificati
Externí odkaz:
https://doaj.org/article/c01905b3c96349fa9c33036d200fdba5