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pro vyhledávání: '"shotgun lipidomics"'
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Akademický článek
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Autor:
Yitian Zhu, Luyun Zhang, Xiafeng Zhang, Dehong Wu, Leiming Chen, Changfeng Hu, Chengping Wen, Jia Zhou
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, and the dysregulation of lipid metabolism has been found to play an important role in the pathogenesis of RA and is related to the severity and prognosis of patients. Tripterygiu
Externí odkaz:
https://doaj.org/article/cb8d93abef034095bdbe05eba4a1ba2c
Autor:
Maren Rudolph, Yuting Wang, Theresa Simolka, Emilie Huc-Claustre, Lingyun Dai, Gijsbert Grotenbreg, Gurdyal Singh Besra, Anna Shevchenko, Andrej Shevchenko, Sebastian Zeissig
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD1d is an atypical MHC class I molecule which binds endogenous and exogenous lipids and can activate natural killer T (NKT) cells through the presentation of lipid antigens. CD1d surveys different cellular compartments including the secretory and th
Externí odkaz:
https://doaj.org/article/ce90314b62184a15b77ee1f947741d7e
Autor:
Pål A. Olsvik, Liv Søfteland
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 547-558 (2020)
Pesticide formulations typically contain adjuvants added to enhance the performance of the active ingredient. Adjuvants may modify the bioavailability and toxicity of pesticides. In this study, the aim was to examine to which degree nonylphenol (NP)
Externí odkaz:
https://doaj.org/article/4171fa138b0b48e38eabf3a0c9866584
Autor:
Ernesto Rodriguez-Ayala, Esther C. Gallegos-Cabrales, Laura Gonzalez-Lopez, Hugo A. Laviada-Molina, Rocio A. Salinas-Osornio, Edna J. Nava-Gonzalez, Irene Leal-Berumen, Claudia Escudero-Lourdes, Fabiola Escalante-Araiza, Fatima A. Buenfil-Rello, Vanessa-Giselle Peschard, Antonio Laviada-Nagel, Eliud Silva, Rosa A. Veloz-Garza, Angelica Martinez-Hernandez, Francisco M. Barajas-Olmos, Fernanda Molina-Segui, Lucia Gonzalez-Ramirez, Rebeca Espadas-Olivera, Ricardo Lopez-Muñoz, Ruy D. Arjona-Villicaña, Victor M. Hernandez-Escalante, Martha E. Rodriguez-Arellano, Janeth F. Gaytan-Saucedo, Zoila Vaquera, Monica Acebo-Martinez, Judith Cornejo-Barrera, Huertas-Quintero Jancy Andrea, Juan Carlos Castillo-Pineda, Areli Murillo-Ramirez, Sara P. Diaz-Tena, Benigno Figueroa-Nuñez, Melesio E. Valencia-Rendon, Rafael Garzon-Zamora, Juan Manuel Viveros-Paredes, José Ángeles-Chimal, Jesús Santa-Olalla Tapia, José M. Remes-Troche, Salvador B. Valdovinos-Chavez, Eira E. Huerta-Avila, Juan Carlos Lopez-Alvarenga, Anthony G Comuzzie, Karin Haack, Xianlin Han, Lorena Orozco, Susan Weintraub, Jack W. Kent, Shelley A. Cole, Raul A. Bastarrachea
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 153-169 (2020)
Interactions between macrophages and adipocytes are early molecular factors influencing adipose tissue (AT) dysfunction, resulting in high leptin, low adiponectin circulating levels and low-grade metaflammation, leading to insulin resistance (IR) wit
Externí odkaz:
https://doaj.org/article/8577020c914e4732aeeacfa3a2386dda
Autor:
Vanda Varga-Zsíros, Ede Migh, Annamária Marton, Zoltán Kóta, Csaba Vizler, László Tiszlavicz, Péter Horváth, Zsolt Török, László Vígh, Gábor Balogh, Mária Péter
Publikováno v:
Cells, Vol 12, Iss 3, p 428 (2023)
Lipid metabolic disturbances are associated with several diseases, such as type 2 diabetes or malignancy. In the last two decades, high-performance mass spectrometry-based lipidomics has emerged as a valuable tool in various fields of biology. Howeve
Externí odkaz:
https://doaj.org/article/4a89c021861b46ab89c7a7844a67f60c
Autor:
Iliya Lefterov, Cody M. Wolfe, Nicholas F. Fitz, Kyong Nyon Nam, Florent Letronne, Richard J. Biedrzycki, Julia Kofler, Xianlin Han, Jianing Wang, Jonathan Schug, Radosveta Koldamova
Publikováno v:
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background The application of advanced sequencing technologies and improved mass-spectrometry platforms revealed significant changes in gene expression and lipids in Alzheimer’s disease (AD) brain. The results so far have prompted further
Externí odkaz:
https://doaj.org/article/ec23950c70644aa5888106a51ae0e5fd
Autor:
Olga Vvedenskaya, Tim Daniel Rose, Oskar Knittelfelder, Alessandra Palladini, Judith Andrea Heidrun Wodke, Kai Schuhmann, Jacobo Miranda Ackerman, Yuting Wang, Canan Has, Mario Brosch, Veera Raghavan Thangapandi, Stephan Buch, Thomas Züllig, Jürgen Hartler, Harald C. Köfeler, Christoph Röcken, Ünal Coskun, Edda Klipp, Witigo von Schoenfels, Justus Gross, Clemens Schafmayer, Jochen Hampe, Josch Konstantin Pauling, Andrej Shevchenko
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100104- (2021)
Nonalcoholic fatty liver disease (NAFLD) is a common metabolic dysfunction leading to hepatic steatosis. However, NAFLD's global impact on the liver lipidome is poorly understood. Using high-resolution shotgun mass spectrometry, we quantified the mol
Externí odkaz:
https://doaj.org/article/baf15b6381f843daa555ad1b8cabc9ef
Akademický článek
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