Zobrazeno 1 - 10
of 4 347
pro vyhledávání: '"sh-sy5y cells"'
Autor:
Daiki Wakasugi, Shinji Kondo, Farhana Ferdousi, Seiya Mizuno, Akira Yada, Kenichi Tominaga, Satoru Takahashi, Hiroko Isoda
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Neuroinflammation is widely acknowledged as a characteristic feature of almost all neurological disorders and specifically in depression- and anxiety-like disorders. In recent years, there has been significant attention on natural
Externí odkaz:
https://doaj.org/article/aa38080127454026ba327a1978b6802f
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 8, Pp 103319- (2024)
Objectives: Huntington's disease is an incurable neurodegenerative disease caused by a huntingtin gene defect; it causes changes in the brain, which affect movement and mental functions. The molecular mechanism still challenges the research to find t
Externí odkaz:
https://doaj.org/article/38d08d80b5e94e0aacb7cba2a691dbdf
Autor:
Jennifer McDonough, Naveen K. Singhal, Paulina M. Getsy, Katherine Knies, Zackery T. Knauss, Devin Mueller, James N. Bates, Derek S. Damron, Stephen J. Lewis
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
We have reported that D,L-thiol esters, including D-cysteine ethyl ester (D-CYSee), are effective at overcoming opioid-induced respiratory depression (OIRD) in rats. Our on-going studies reveal that co-injections of D-CYSee with multi-day morphine in
Externí odkaz:
https://doaj.org/article/b770ebd95e5f4062957719f54007718e
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8115-8116 (2024)
Liu J, Kang Y, Yin S, et al. Int J Nanomedicine. 2017;12:8085–8099. The authors have advised the control images for Figure 4A and B were the same to represent the one and the same control group. To alleviate any potential confusion this may have cr
Externí odkaz:
https://doaj.org/article/ec46cfacc91f4de19c397d7107d0e600
Autor:
Yajie Hu, Wei Zhao, Yaming Lv, Hui Li, Jiang Li, Mingmei Zhong, Dandan Pu, Fuping Jian, Jie Song, Yunhui Zhang
Publikováno v:
Virus Research, Vol 345, Iss , Pp 199386- (2024)
Coxsackievirus A16 (CV-A16) and coxsackievirus A10 (CV-A10), more commonly etiological agents of hand, foot and mouth disease (HFMD), are capable of causing severe neurological syndromes with high fatalities, but their neuropathogenesis has rarely be
Externí odkaz:
https://doaj.org/article/c4851c90090047179b5153b88c60a0ff
Autor:
Wen-Wen He, Xiao-Xiao Zeng, Xiao-Lan Qi, Chuan-Zhi Gui, Wei Liao, Xi Tu, Jie Deng, Yang-Ting Dong, Wei Hong, Yan He, Yan Xiao, Zhi-Zhong Guan
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116467- (2024)
Background: Although the changes of mitogen-activated protein kinase (MAPK) pathway in the central nervous system (CNS) induced by excessive fluoride has been confirmed by our previous findings, the underlying mechanism(s) of the action remains uncle
Externí odkaz:
https://doaj.org/article/2a38e158828b4445aac9af2b63408a1b
Autor:
Stefano Castellani, Giorgia Natalia Iaconisi, Francesca Tripaldi, Vito Porcelli, Adriana Trapani, Eugenia Messina, Lorenzo Guerra, Cinzia Di Franco, Giuseppe Maruccio, Anna Grazia Monteduro, Filomena Corbo, Sante Di Gioia, Giuseppe Trapani, Massimo Conese
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1048 (2024)
This work aimed to evaluate the potential of the nanosystems constituted by dopamine (DA) and the antioxidant Citicoline (CIT) co-loaded in solid lipid nanoparticles (SLNs) for intranasal administration in the treatment of Parkinson disease (PD). Suc
Externí odkaz:
https://doaj.org/article/1f1ab735209c4911b1f6e1e0eb162bb7
Akademický článek
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by the accumulation of amyloid beta (Aβ) in brain. Mounting evidence has revealed critical roles of microRNAs (miRNAs) in AD pathogenesis; however, the miRNAs direc
Externí odkaz:
https://doaj.org/article/24f28c49a6ea467a97e6d589f80aa598
Autor:
Alice Pifferi, Elda Chiaino, Jesus Fernandez-Abascal, Aoife C. Bannon, Gavin P. Davey, Maria Frosini, Massimo Valoti
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7439 (2024)
Human individual differences in brain cytochrome P450 (CYP) metabolism, including induction, inhibition, and genetic variation, may influence brain sensitivity to neurotoxins and thus participate in the onset of neurodegenerative diseases. The aim of
Externí odkaz:
https://doaj.org/article/233cf8740bc34a78afce9bd2cd059b76