Výsledky vyhledávání

Akademický článek

Co-expression of P53 and P60-katanin shapes transcriptome dynamics

Autor: Şirin Korulu

Publikováno v: Trakya University Journal of Natural Sciences, Vol 25, Iss 2, Pp 197-201 (2024)

Microtubules (MT), essential elements of the cytoskeleton have important roles in the cell such as intracellular cargo transport, cell motility and cell division. They provide support, growth and maintenance of the axonal and dendritic processes in n

Externí odkaz: https://doaj.org/article/8441a79f286c4532a8f6dbde5feb6dd3

Zobrazit plný text záznamu

Akademický článek

Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation

Autor: Min Luo, Yanying Wang, Jinxiu Liang, Xinhua Wan

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Abstract Background Hereditary spastic paraplegia (HSP) is a rare genetically heterogeneous neurodegenerative disorder. The most common type of HSP is caused by pathogenic variants in the SPAST gene. Various hypotheses regarding the pathogenic mechan

Externí odkaz: https://doaj.org/article/c41d8fbefd9e4596bb32d817d179eef3

Zobrazit plný text záznamu

Plný text ve formátu HTML

Periodical

A Severing.

Autor: Romines, Angie

Publikováno v: New England Review (10531297). 2023, Vol. 44 Issue 4, p57-65. 9p.

Zobrazit plný text záznamu

Akademický článek

Impact of Root Cutting on Acer platanoides and Tilia cordata Tree Stability in Urban Parks: A Case Study in Quebec City, Canada

Autor: Clément Pallafray, Sivajanani Sivarajah, Jean-Claude Ruel

Publikováno v: Forests, Vol 15, Iss 6, p 1041 (2024)

Trees growing in urban environments are often impacted by maintenance or construction work involving the cutting of roots. Tree protection zones have been proposed to avoid critical damage to the tree. However, despite incorporating quantitative info

Externí odkaz: https://doaj.org/article/1f0b49125b674265856447ab2d2da4e4

Zobrazit plný text záznamu

Akademický článek

Inhibition of spastin impairs motor function recovery after spinal cord injury

Autor: Jie Yang, Yunlong Zhang, Zhenbin Cai, Jianyu Zou, Shaojin Li, Guiqiang Miao, Hongsheng Lin, Xiaodong Zhao, Minghui Tan

Publikováno v: Brain Research Bulletin, Vol 205, Iss , Pp 110806- (2023)

Promoting axonal regeneration is an effective strategy for recovery from traumatic spinal cord injury (SCI). Spastin, a microtubule-severing protein, modulates axonal outgrowth and branch formation by regulating microtubule dynamics. However, the exa

Externí odkaz: https://doaj.org/article/fc61acd6f9de4433a6ec1490d9fd52fc

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

Autor: Yunlong Zhang, Xin He, Jianyu Zou, Jie Yang, Ao Ma, Minghui Tan

Publikováno v: European Journal of Histochemistry, Vol 67, Iss 1 (2023)

Spastin, a microtubule-severing enzyme, is known to be important for neurite outgrowth. However, the role of spastin post-translational modification, particularly its phosphorylation regulation in neuronal outgrowth, remains unclear. This study aimed

Externí odkaz: https://doaj.org/article/e2d4ae9bf0a44d68b4ceedf5486536b6

Zobrazit plný text záznamu