Zobrazeno 1 - 10
of 283
pro vyhledávání: '"serpinc1"'
Autor:
Nina Iversen, Carola Elisabeth Henriksson, Marit Sletten, Marie Skogstad Le, Beate Rikken Lindberg, Rune Andersen, Benedicte Paus
Publikováno v:
Thrombosis Journal, Vol 22, Iss 1, Pp 1-5 (2024)
Abstract Background Atresia of the infrarenal inferior vena cava (IVC) is associated with thrombophilia and antithrombin (AT) deficiency (ATD) due to homozygosity for the so-called Budapest 3 variant, c.391C > T, in the gene, SERPINC1. Case presentat
Externí odkaz:
https://doaj.org/article/a949bc1e11ec48edbd86983aaf3048e9
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102126- (2024)
Objectives: Caner-derived exosomes, containing diverse nucleic acids and proteins, are being exploited in diagnostic biomarker development. This study aims to screen and identify the altered exosomal proteins between epithelial ovarian cancer (EOC) p
Externí odkaz:
https://doaj.org/article/9a53e449ea7641b19d2e40f9a5876a58
Autor:
Marco-Rico A, Marco-Vera P
Publikováno v:
Journal of Blood Medicine, Vol Volume 14, Pp 499-506 (2023)
Ana Marco-Rico,1,2 Pascual Marco-Vera2,3 1Hemostasis and Thrombosis Department, Hematology Service, University General Hospital Dr. Balmis, Alicante, Spain; 2Biomedical Research Institute (ISABIAL), Alicante, Spain; 3Clinical Medicine Department, Mig
Externí odkaz:
https://doaj.org/article/97ccadc5b4fe4156b87e093f48130b3f
Autor:
Javier Cuenca-Guardiola, Belén de la Morena-Barrio, Juan L. García, Alba Sanchis-Juan, Javier Corral, Jesualdo T. Fernández-Breis
Publikováno v:
Journal of Advanced Research, Vol 50, Iss , Pp 145-158 (2023)
Introduction: Whole-genome sequencing using nanopore technologies can uncover structural variants, which are DNA rearrangements larger than 50 base pairs. Nanopore technologies can also characterize their boundaries with single-base accuracy, owing t
Externí odkaz:
https://doaj.org/article/e0c75bf3cae14b18b5e67066ff4e599c
Autor:
Judit Kállai, Réka Gindele, Krisztina Pénzes-Daku, Gábor Balogh, Réka Bogáti, Bálint Bécsi, Éva Katona, Zsolt Oláh, Péter Ilonczai, Zoltán Boda, Ágnes Róna-Tas, László Nemes, Imelda Marton, Zsuzsanna Bereczky
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2893 (2024)
Antithrombin (AT) is the major plasma inhibitor of thrombin (FIIa) and activated factor X (FXa), and antithrombin deficiency (ATD) is one of the most severe thrombophilic disorders. In this study, we identified nine novel AT mutations and investigate
Externí odkaz:
https://doaj.org/article/d3799ccc75994a64a076a6fd41045381
Autor:
D. Denora, M. V. Di Rosa, N. Altamura, F. Pellicori, P. Vinci, U. G. Sisto, F. Spanò, F. G. Di Girolamo, N. Fiotti, G. Biolo
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-3 (2023)
Abstract Background SERPINC1 is a glycoprotein that regulates blood coagulation. SERPINC1 congenital or acquired deficiencies represent a significant risk factor for thromboembolic disease. SERPINC1 acquired defects are observed in very few cases and
Externí odkaz:
https://doaj.org/article/c676d6c71f444f08aabdf0e2405b07ac
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/ec775befcb79423dac2c3463b8f10869
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Hereditary antithrombin-III deficiency can significantly increase the risk for thrombosis, which is common in limb deep vein and pulmonary cases. However, thrombotic microangiopathy (TMA) caused by hereditary antithrombin deficiency is
Externí odkaz:
https://doaj.org/article/bbc72308e3a34155bcfb146929aa4095
Autor:
Young-Eun Kim, Eun-Ju Lee, Kyunggon Kim, Do Hoon Kim, Mi Ryeong Jeong, Jiyoung Yu, Seokchan Hong, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundTo evaluate the usefulness of urine SERPINC1 and ORM1 as biomarkers for early detection of lupus nephritis (LN).MethodsUsing proteomics, we screened for potential urine biomarkers that differentiate LN from systemic lupus erythematosus (SLE
Externí odkaz:
https://doaj.org/article/70bb1fd09752483e90a0c1aaa757f521
Autor:
Han-lu Wang, Dan-dan Ruan, Min Wu, Yuan-yuan Ji, Xing-xing Hu, Qiu-yan Wu, Yan-ping Zhang, Bin Lin, Ya-nan Hu, Hang Wang, Yi Tang, Zhu-ting Fang, Jie-wei Luo, Li-sheng Liao, Mei-zhu Gao
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Antithrombin (AT) is the main physiological anticoagulant involved in hemostasis. Hereditary AT deficiency is a rare autosomal dominant thrombotic disease mainly caused by mutations in SERPINC1, which was usually manifested as ven
Externí odkaz:
https://doaj.org/article/a5108f9fe13c4116a33ad7724035f686