Zobrazeno 1 - 10
of 718
pro vyhledávání: '"serpina1"'
Autor:
Edita Poluzioroviene, Joanna Chorostowska-Wynimko, Sigita Petraitiene, Arunas Strumila, Adriana Rozy, Aneta Zdral, Arunas Valiulis
Publikováno v:
Advances in Respiratory Medicine, Vol 92, Iss 4, Pp 291-299 (2024)
Severe inherited alpha-1 antitrypsin deficiency (AATD) is an autosomal genetic condition linked to chronic obstructive pulmonary disease (COPD). The significance of heterozygous, milder deficiency variants (PiSZ, PiMZ, PiMS) is less clear. We studied
Externí odkaz:
https://doaj.org/article/8859bf38c0a74bd6b83656c53b036ad7
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Alpha1-antitrypsin (AAT) is a serine protease inhibitor that serves as a counterbalance to the activity of elastases, e.g., neutrophil elastase in lung tissue. AAT deficiency (AATD) is a rare disorder usually arising from mutation
Externí odkaz:
https://doaj.org/article/184eac18ce0a4231a243c969e954a6f8
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Alpha 1 Antitrypsin Deficiency (AATD) is a largely underrecognized genetic condition characterized by low Alpha 1 Antitrypsin (AAT) serum levels, resulting from variations in SERPINA1. Many individuals affected by AATD are thought
Externí odkaz:
https://doaj.org/article/ff00a0ca8ac14d42bce60277f6f24f36
Autor:
Styliani Sarrou, Ioanna Voulgaridi, Athanasia Fousika, Katerina Dadouli, Olympia Margaritopoulou, Ioannis Kakkas, Christos Hadjichristodoulou, Fani Kalala, Matthaios Speletas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5382 (2024)
Patients with predominantly antibody deficiencies (PADs) display hypogammaglobulinemia with a high prevalence of infections, along with autoimmune manifestations, benign and malignant lymphoproliferation and granulomatous disease. It is noteworthy th
Externí odkaz:
https://doaj.org/article/560fd789632a4e3b8ce7fd2954a19120
Autor:
Angel Gonzalez, Irene Belmonte, Alexa Nuñez, Georgina Farago, Miriam Barrecheguren, Mònica Pons, Gerard Orriols, Pablo Gabriel-Medina, Francisco Rodríguez-Frías, Marc Miravitlles, Cristina Esquinas
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-13 (2022)
Abstract Background Alpha-1 antitrypsin deficiency (AATD) is characterized by reduced serum levels of the AAT protein and predisposes to liver and lung disease. The characterization at structural level of novel pathogenic SERPINA1 mutants coding for
Externí odkaz:
https://doaj.org/article/394c553703d74010bc646f421ba4fe36
Publikováno v:
Open Medicine, Vol 17, Iss 1, Pp 1645-1654 (2022)
Serpin family A member 1 (SERPINA1) is expressed abundantly in gliomas and can predict unfavorable prognosis of patients with glioma. Studies have shown that nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1 (NQO1) can promote the p
Externí odkaz:
https://doaj.org/article/58eb5c0cd57948dd920059306e0498b2
Publikováno v:
International Journal of COPD, Vol Volume 17, Pp 2117-2125 (2022)
Li Yue Zhang,1,2,* Xian Wen Sun,1,2,* Yong Jie Ding,1,2,* Ya Ru Yan,1,2 Yi Wang,1,2 Chuan Xiang Li,1– 3 Shi Qi Li,1,2 Liu Zhang,1,2 He Jie Song,1,2 Hong Peng Li,1,2 Qing Yun Li1,2 1Department of Respiratory and Critical Care Medicine, R
Externí odkaz:
https://doaj.org/article/13ccdbb2e6d84141adc8dc5d64bd1181
Autor:
Yihan Zhang, Xin Xie, Hong Zhou, Bingxin Li, Li Ding, Zhaogen Cai, Huaidong Song, Shuangxia Zhao, Huanbai Xu
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundHashimoto’s thyroiditis (HT) is an autoimmune thyroid disease. Papillary thyroid carcinoma (PTC) is the most common endocrine cancer. In recent years the rate of coexistence between PTC and HT has increased but the relationship between th
Externí odkaz:
https://doaj.org/article/07437be0747b4c49bf1f7b37d4e78b0a
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