Zobrazeno 1 - 10
of 493
pro vyhledávání: '"serine/threonine phosphatase"'
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Toll-like receptors (TLRs) are critical sensors for the detection of potentially harmful microbes. They are instrumental in initiating innate and adaptive immune responses against pathogenic organisms. However, exaggerated activation of TLR
Externí odkaz:
https://doaj.org/article/66daff73de5342688e07a006799feb39
Autor:
Jie-Jie Xu, Lin Zhu, Hai-Di Li, Xiao-Sa Du, Juan-Juan Li, Na-Na Yin, Xiao-Ming Meng, Cheng Huang, Jun Li
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106125- (2022)
Alcohol-induced liver injury (ALI) is associated with inflammatory responses regulated by macrophages. Activation of macrophages plays a crucial role in ALI while DNA methylation-regulated gene silencing is associated with inflammation processes in m
Externí odkaz:
https://doaj.org/article/00c9a3fad48b4846b7c954aefc9369f4
Akademický článek
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Autor:
Holly Fowle, Ziran Zhao, Qifang Xu, Jason S Wasserman, Xinru Wang, Mary Adeyemi, Felicity Feiser, Alison N Kurimchak, Diba Atar, Brennan C McEwan, Arminja N Kettenbach, Rebecca Page, Wolfgang Peti, Roland L Dunbrack, Xavier Graña
Publikováno v:
eLife, Vol 10 (2021)
Protein phosphorylation is a reversible post-translation modification essential in cell signaling. This study addresses a long-standing question as to how the most abundant serine/threonine protein phosphatase 2 (PP2A) holoenzyme, PP2A/B55α, specifi
Externí odkaz:
https://doaj.org/article/6761c6a9c42749159283c5b22082407f
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Proline-serine-threonine-phosphatase-interacting protein 2 (PSTPIP2) belongs to the Fes/CIP4 homology-Bin/Amphiphysin/Rvs (F-BAR) domain family. It exhibits lipid-binding, membrane deformation, and F-actin binding activity, suggesting broader roles a
Externí odkaz:
https://doaj.org/article/8b71e5ecb0214f6ebcd7e9ab81e71aaa
Autor:
Ulrich Baumgartner, Fabienne Berger, Ali Hashemi Gheinani, Sabrina Sofia Burgener, Katia Monastyrskaya, Erik Vassella
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background Epidermal growth factor receptor (EGFR) mutations enable constitutive active downstream signaling of PI3K/AKT, KRAS/ERK and JAK/STAT pathways, and promote tumor progression by inducing uncontrolled proliferation, evasion of apopto
Externí odkaz:
https://doaj.org/article/95c3a3d11c214e69b344341aa065c8a9
Autor:
Qiao Hu, Lun Yao, Xia Liao, Liang-Sheng Zhang, Hao-Tian Li, Ting-Ting Li, Qing-Gen Jiang, Mei-Fang Tan, Lu Li, Roger R. Draheim, Qi Huang, Rui Zhou
Publikováno v:
Microorganisms, Vol 9, Iss 12, p 2442 (2021)
Eukaryote-like serine/threonine kinases (STKs) and cognate phosphatases (STPs) comprise an important regulatory system in many bacterial pathogens. The complexity of this regulatory system has not been fully understood due to the presence of multiple
Externí odkaz:
https://doaj.org/article/9c5a119d548f453680a3ee310247ffcb
Akademický článek
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Autor:
Muhammad Ehsan, WenJuan Wang, Javaid Ali Gadahi, Muhammad Waqqas Hasan, MingMin Lu, YuJian Wang, XinChao Liu, Muhammad Haseeb, RuoFeng Yan, LiXin Xu, XiaoKai Song, XiangRui Li
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Serine/threonine-protein phosphatases (STPs), as integral constituents of parasitic excretory/secretory proteins, are assumed to be released during the host–parasite interactions. However, knowledge about these phosphatases and their immunoregulato
Externí odkaz:
https://doaj.org/article/5b604652c6eb4e38adc1fa7b5f251970
Akademický článek
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