Zobrazeno 1 - 10
of 7 352
pro vyhledávání: '"sequencing data"'
Autor:
Youshu Cheng, Biao Cai, Hongyu Li, Xinyu Zhang, Gypsyamber D’Souza, Sadeep Shrestha, Andrew Edmonds, Jacquelyn Meyers, Margaret Fischl, Seble Kassaye, Kathryn Anastos, Mardge Cohen, Bradley E. Aouizerat, Ke Xu, Hongyu Zhao
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Methylation quantitative trait loci (meQTLs) quantify the effects of genetic variants on DNA methylation levels. However, most published studies utilize bulk methylation datasets composed of different cell types and limit our understanding o
Externí odkaz:
https://doaj.org/article/c6b0a2734db1434f9dcd7daf066bd2c6
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Increasingly, scRNA-Seq studies explore cell populations across different samples and the effect of sample heterogeneity on organism’s phenotype. However, relatively few bioinformatic methods have been developed which adequately address th
Externí odkaz:
https://doaj.org/article/63f57038731f451190d9327b3cc02021
Autor:
Yan Zheng, Xuequn Shang
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Structural variations play a significant role in genetic diseases and evolutionary mechanisms. Extensive research has been conducted over the past decade to detect simple structural variations, leading to the development of well-e
Externí odkaz:
https://doaj.org/article/203bffa7bf7c4d06bb91035035db6a88
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-9 (2024)
Abstract Background The international disclosure of Chinese human genetic data continues to be a contentious issue in China, generating public debates in both traditional and social media channels. Concerns have intensified after Chinese scientists
Externí odkaz:
https://doaj.org/article/2c81d5a6013d47b8ade0f734cda063cb
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Open chromatin regions (OCRs) play a crucial role in transcriptional regulation and gene expression. In recent years, there has been a growing interest in using plasma cell-free DNA (cfDNA) sequencing data to detect OCRs. By analyzing the characteris
Externí odkaz:
https://doaj.org/article/d151a02571fb4a418fdab822ccead36b
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 111061- (2024)
Huanglongbing (HLB) is the most serious citrus disease in Vietnam. For the first time, this paper reported root microbial data of HLB-infected Citrus nobilis grown in Dak Lak Province, Vietnam, for further work toward controlling this disease. Roots
Externí odkaz:
https://doaj.org/article/87e3ab36a83349358c227c64ad341a89
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Major advances in sequencing technologies and the sharing of data and metadata in science have resulted in a wealth of publicly available datasets. However, working with and especially curating public omics datasets remains challe
Externí odkaz:
https://doaj.org/article/8d1f9e01f9d349f2ab9e194f3c1cbded
Autor:
Jing, Zhangmu a, b, c, d, 1, Zhang, Yi e, 1, Liu, Xiaoling a, b, Li, Qingqian a, b, Hao, Yanji f, Li, Yeqing f, Gao, Hongjie a, b, c, ⁎
Publikováno v:
In Environment International January 2025 195
Publikováno v:
mSystems, Vol 9, Iss 10 (2024)
ABSTRACT While numerous computational frameworks and workflows are available for recovering prokaryote and eukaryote genomes from metagenome data, only a limited number of pipelines are designed specifically for viromics analysis. With many viromics
Externí odkaz:
https://doaj.org/article/466d9153d7a947ac8e0f52e6a6d94b8d
Autor:
Qiuyu Zhang, Wenjie Cao, Jiaqi Wang, Yihao Yin, Rui Sun, Zunyi Tian, Yuhan Hu, Yalan Tan, Ben-gong Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Gene transcription is a stochastic process that occurs in all organisms. Transcriptional bursting, a critical molecular dynamics mechanism, creates significant heterogeneity in mRNA and protein levels. This heterogeneity drives cellular phenotypic di
Externí odkaz:
https://doaj.org/article/2fe8a622487e4cfbb2782596066612c6