CTLA-4 expression on CD4+ lymphocytes in patients with sepsis-associated immunosuppression and its relationship to mTOR mediated autophagic–lysosomal disorder

Autor: Wei Cheng, Jiahui Zhang, Dongkai Li, Xianli Lei, Hao Wang, Na Cui

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundThe aim of this study was to clarify the relationship between expression level of CTLA-4 on CD4+ T cells and sepsis-associated immunosuppression (SAI), and to elucidate the possible mechanism of mTOR pathway mediated autophagic-lysosomal di

Externí odkaz: https://doaj.org/article/06566327249f474eaa53cde469b82ba1

Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers

Autor: Carmen Andrea Pfortmueller, Christian Meisel, Michaela Fux, Joerg C. Schefold

Publikováno v: Intensive Care Medicine Experimental, Vol 5, Iss 1, Pp 1-16 (2017)

Abstract In critically ill patients, organ dysfunctions are routinely assessed, monitored, and treated. Mounting data show that substantial critical illness-induced changes in the immune system can be observed in most ICU patients and that not only �

Externí odkaz: https://doaj.org/article/6dc64d0d4371414ca399cdfeb7ad5101

Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers

Autor: Joerg C. Schefold, Carmen A. Pfortmueller, Michaela Fux, Christian Meisel

Publikováno v: Pfortmüller, Carmen; Meisel, Christian; Fux, Michaela; Schefold, Joerg C. (2017). Assessment of immune organ dysfunction in critical illness: utility of innate immune response markers. Intensive care medicine experimental, 5(1), p. 49. Springer 10.1186/s40635-017-0163-0
Intensive Care Medicine Experimental, Vol 5, Iss 1, Pp 1-16 (2017)
Intensive Care Medicine Experimental

In critically ill patients, organ dysfunctions are routinely assessed, monitored, and treated. Mounting data show that substantial critical illness-induced changes in the immune system can be observed in most ICU patients and that not only “hyper-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21569045174d338e6ffeb69b432c1cf4

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