Zobrazeno 1 - 10
of 200
pro vyhledávání: '"sepsis model"'
Autor:
Nateelak Kooltheat, Amethyst Chaiissarapap, Onanong Jienthaisong, Nutchanok Mohlek, Rungnapa Pankla Sranujit, Nuttikarn Nokkaew
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research, Vol 12, Iss 3, Pp 594-605 (2024)
Context: Sepsis is a progressive inflammatory response commonly caused by gram-negative bacteria via activation of the NF-κB-dependent pathway. Severe sepsis can cause cardiac dysfunction and increases the risk of death. Artemisia lactiflora is a Ch
Externí odkaz:
https://doaj.org/article/871ea018ea7c48a185df9a4d64d06b95
Autor:
Tsung-Ying Yang, Wei-Chun Hung, Tsung-Han Tsai, Po-Liang Lu, Sheng-Fan Wang, Liang-Chun Wang, Yu-Tzu Lin, Sung-Pin Tseng
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 5, Pp 1016-1025 (2023)
Background: The issue of carbapenem-resistant Escherichia coli was aggravated yearly. The previous studies reported the varied but critical epidemiology of carbapenem-resistant E. coli among which the carbapenemase-producing strains were regarded as
Externí odkaz:
https://doaj.org/article/36df3c4289264c379d3abcfeca6bc293
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundIndividual T cell responses vary significantly based on the microenvironment present at the time of immune response and on prior induced T cell memory. While the cecal ligation and puncture (CLP) model is the most commonly used murine sepsi
Externí odkaz:
https://doaj.org/article/02cd320690e34be9a06ede34ef7de0da
Autor:
Paul Skorup, Anette Fransson, Jenny Gustavsson, Johan Sjöholm, Henrik Rundgren, Volkan Özenci, Alicia Y. W. Wong, Tomas Karlsson, Christer Svensén, Mattias Günther
Publikováno v:
Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract Background Sepsis is associated with substantial mortality rates. Antibiotic treatment is crucial, but global antibiotic resistance is now classified as one of the top ten global public health risks facing humanity. Ozone (O3) is an inorgani
Externí odkaz:
https://doaj.org/article/7bbd886aa9dd4e99aee56270bd782aae
Publikováno v:
Mediterranean Journal of Infection, Microbes and Antimicrobials, Vol 11, Iss 1 (2022)
Introduction: To investigate the efficacy of double carbapenem therapy (ertapenem + meropenem combination) in an experimental sepsis model in rats with Klebsiella pneumoniae (K. pneumoniae), which is carbapenem-resistant and colistin susceptible, and
Externí odkaz:
https://doaj.org/article/dad566199f884e3792cd6b401efef07f
Autor:
Steven R. Talbot, Birgitta Struve, Laura Wassermann, Miriam Heider, Nora Weegh, Tilo Knape, Martine C. J. Hofmann, Andreas von Knethen, Paulin Jirkof, Christine Häger, André Bleich
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Good science in translational research requires good animal welfare according to the principles of 3Rs. In many countries, determining animal welfare is a mandatory legal requirement, implying a categorization of animal suffering, traditionally domin
Externí odkaz:
https://doaj.org/article/a4fc9e7b330b43b6bb9893ea57bb909b
Publikováno v:
Heliyon, Vol 8, Iss 8, Pp e10236- (2022)
Sepsis is a major cause of death in intensive care units whose development is supported by an imbalance of oxidative stress and antioxidant. Superoxide dismutase (SOD) is a primer endogen antioxidant that prevents reactive oxygen species (ROS). Exten
Externí odkaz:
https://doaj.org/article/d9870f7739934bdeaad9b95def0b8efa
Autor:
Julia Elrod, Antonia Kiwit, Moritz Lenz, Holger Rohde, Daniela Börnigen, Malik Alawi, Christoph Mohr, Laia Pagerols Raluy, Magdalena Trochimiuk, Jasmin Knopf, Konrad Reinshagen, Martin Herrmann, Michael Boettcher
Publikováno v:
Cells, Vol 12, Iss 3, p 366 (2023)
Background: Severe infections that culminate in sepsis are associated with high morbidity and mortality. Despite continuous efforts in basis science and clinical research, evidence based-therapy is mostly limited to basic causal and supportive measur
Externí odkaz:
https://doaj.org/article/a291d6d95d1e4823a6db3c4e30643137
Autor:
Irene Merino, Stephen B. Porter, Brian Johnston, Connie Clabots, Paul Thuras, Patricia Ruiz-Garbajosa, Rafael Cantón, James R. Johnson
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 327-336 (2020)
Background: Escherichia coli ST131, mainly its H30 clade, is the leading cause of extraintestinal E. coli infections but its correlates of virulence are undefined. Materials and methods: We tested in a murine sepsis model 84 ST131 isolates that diffe
Externí odkaz:
https://doaj.org/article/a6121412f42142cf8f2a4f9e1c9088a3
Publikováno v:
Eurasian Journal of Veterinary Sciences, Vol 36, Iss 3, Pp 221-231 (2020)
Aim: Sepsis is a fatal serious clinical disorder. The oxidative stress in sepsis plays an important role in the inflammation. Therefore, the effects of oleuropein (OLE) and ceftriaxone (CEFT) on sepsis were investigated in this study. Materials and M
Externí odkaz:
https://doaj.org/article/5bd1c5f5d752480da6f6913510611c4a