Zobrazeno 1 - 10
of 1 094
pro vyhledávání: '"senescent cells"'
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 8797-8813 (2024)
Yurou Shi,1,2,* Yingjie Zhang,1,* Yaxuan Zhang,2 Jiali Yao,2 Junping Guo,3 Xiaoling Xu,2 Lijun Wang1 1Geriatric Medicine Center, Department of Endocrinology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou M
Externí odkaz:
https://doaj.org/article/55fe2399689541f7a2832a97911ddfc9
Publikováno v:
Медицинская иммунология, Vol 26, Iss 4, Pp 693-700 (2024)
Tumor-associated macrophages (TAMs) are an important and most represented population of immune cells in the tumor microenvironment. To a great extent, TAMs can determine the direction of the antitumor immune response; they can either additionally sti
Externí odkaz:
https://doaj.org/article/f40a5d35cae14020b618e85242676dbb
Autor:
Xuewen Deng, Hiroshi Terunuma
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-6 (2024)
Abstract The aging process intricately involves immune system dynamics, with a crucial role in managing senescent cells (SNCs) and their senescence-associated secretory phenotypes (SASPs). Unfortunately, immunosenescence, a progressively dysregulated
Externí odkaz:
https://doaj.org/article/b03f64d0b4c348818782b05e8a5d96a8
Autor:
Luciana Polaco Covre, Carlos Henrique Fantecelle, Renan Garcia de Moura, Paola Oliveira Lopes, Isabela Valim Sarmento, Celio Geraldo Freire-de-Lima, Debora Decote-Ricardo, Herbert Leonel de Matos Guedes, Alessandra Marcia da Fonsceca-Martins, Lucas Pedreira de Carvalho, Edgar Marcelino de Carvalho, David M. Mosser, Aloisio Falqueto, Arne N. Akbar, Daniel Claudio Oliveira Gomes
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytotoxic activity is a hallmark of the immunopathogenesis in human cutaneous leishmaniasis (CL). In this study, we identified accumulation of CD4+ granzyme B producing T cells with increased cytotoxic capacity in CL lesions. These cells showed enhan
Externí odkaz:
https://doaj.org/article/62e70576cb3d4ad59dcb11eebedd7965
Autor:
Jacky C. H. Chu, Blanca Escriche‐Navarro, Junlong Xiong, Alba García‐Fernández, Ramón Martínez‐Máñez, Dennis K. P. Ng
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Senescence is a cellular response having physiological and reparative functions to preserve tissue homeostasis and suppress tumor growth. However, the accumulation of senescent cells would cause deleterious effects that lead to age‐related
Externí odkaz:
https://doaj.org/article/df8a638fa775424590b9176e5dc2f2b5
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Introduction Therapy‐induced senescent cancer and stromal cells secrete cytokines and growth factors to promote tumor progression. Therefore, senescent cells may be novel targets for tumor treatment. Near‐infrared photoimmunotherapy (NIR
Externí odkaz:
https://doaj.org/article/71582fe5c90e42cca354aada49a0e70e
Autor:
Lev Salnikov
Publikováno v:
Translational Medicine of Aging, Vol 8, Iss , Pp 29-32 (2024)
The role of the endoplasmic reticulum (ER) in aging processes has not attracted much attention of researchers, while this structure plays one of the central roles in the processes of intracellular synthesis. Summarizing the data presented in this rev
Externí odkaz:
https://doaj.org/article/5bf6c6b8c8444473890a60f994d5f19e
Autor:
Verónica Díaz-Hernández, Alejandro Marmolejo-Valencia, César Montiel-De la Cruz, Gabriela Piñón-Zárate, Luis M. Montaño, Silvia Ivonne Mora-Herrera, Ivette Caldelas
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9906 (2024)
The aging ovary in mammals leads to the reduced production of sex hormones and a deterioration in follicle quality. The interstitial gland originates from the hypertrophy of the theca cells of atretic follicles and represents an accumulative structur
Externí odkaz:
https://doaj.org/article/34ac17b1320c46f48d43ca9a0ee93937
Autor:
E.V. Trizno
Publikováno v:
Известия высших учебных заведений. Поволжский регион: Медицинские науки, Iss 4 (2024)
Background. Hydrogen sulfide (H2S) in high concentrations is a toxic pollutant. Due to the risk of its impact on the organism of people living in the areas of its production as part of natural gas, it is necessary to expand the pathogenetically subs
Externí odkaz:
https://doaj.org/article/824aed587faa44168e3f163adde98aa4
Autor:
Vasileios Tatanis, Dimitris Veroutis, Pavlos Pantelis, George Theocharous, Helen Sarlanis, Alexandros Georgiou, Angelis Peteinaris, Anastasios Natsos, Napoleon Moulavasilis, Nikolaos Kavantzas, Athanassios Kotsinas, Ioannis Adamakis
Publikováno v:
Archivio Italiano di Urologia e Andrologia (2024)
Purpose: The aim of this experimental study is to investigate the correlation between the presence of senescent cells and the tumor size, the lymphovascular invasion (LVI), the invasion of rete testis (RTI), the preoperative tumor markers or patholog
Externí odkaz:
https://doaj.org/article/3d32f7fe1dde43198337928aef6b969a