Zobrazeno 1 - 10
of 462
pro vyhledávání: '"senescence associated secretory phenotype, (SASP)"'
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-12 (2024)
Abstract Cellular senescence is the state in which cells undergo irreversible cell cycle arrest and acquire diverse phenotypes. It has been linked to chronic inflammation and fibrosis in various organs as well as to individual aging. Therefore, elimi
Externí odkaz:
https://doaj.org/article/732b3e907d6d4697941d8f8b64a4147c
Autor:
Jasper Iske, Hao Zhou
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
Externí odkaz:
https://doaj.org/article/8a89a5fc209a462e9c316e21b63b588f
Autor:
Qi Xu, Xiaoying Feng
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundCellular senescence is a common biological process with a well-established link to cancer. However, the impact of cellular senescence on tumor progression remains unclear. To investigate this relationship, we utilized transcriptomic data fr
Externí odkaz:
https://doaj.org/article/ed339983e8a34977ad96d91e4c686509
Publikováno v:
MedComm, Vol 5, Iss 5, Pp n/a-n/a (2024)
Abstract Aging exhibits several hallmarks in common with cancer, such as cellular senescence, dysbiosis, inflammation, genomic instability, and epigenetic changes. In recent decades, research into the role of cellular senescence on tumor progression
Externí odkaz:
https://doaj.org/article/51f2130c9b6a457c9fa00a731b717ddf
Autor:
Miriam Morente-López, Rocio Mato-Basalo, Sergio Lucio-Gallego, Concha Gil, Mónica Carrera, Juan A. Fafián-Labora, Jesús Mateos, María C. Arufe
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the senescence-associated secretory phenotype (SASP) which characterizes senescent cells and contribut
Externí odkaz:
https://doaj.org/article/6a497dddc75f4ff3b2e13846c4d13617
Autor:
Haonan Fan, Zhi Qiao, Jitian Li, Guowei Shang, Chunfeng Shang, Songfeng Chen, Zikuan Leng, Huifang Su, Hongwei Kou, Hongjian Liu
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25538- (2024)
The worldwide elderly population is on the rise, and aging is a major osteoporosis risk factor. Senescent cells accumulation can have a detrimental effect the body as we age. The senescence-associated secretory phenotype (SASP), an essential cellular
Externí odkaz:
https://doaj.org/article/93ee55ed4f9f4a1a8b5781e8eaab9efc
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
The increasing life expectancy observed in recent years has resulted in a higher prevalence of late-onset hypogonadism (LOH) in older men. LOH is characterized by the decline in testosterone levels and can have significant impacts on physical and men
Externí odkaz:
https://doaj.org/article/6122a67a110d4d359b14ffaae878bba2
Autor:
Ratthapon Somsura, Kanokwan Kamkajon, Khuanjit Chaimongkolnukul, Surachai Chantip, Jarinthorn Teerapornpuntakit, Kannikar Wongdee, Nuntaporn Kamonsutthipaijit, Suwimol Tangtrongsup, Nattapon Panupinthu, Wacharaporn Tiyasatkulkovit, Narattaphol Charoenphandhu
Publikováno v:
PeerJ, Vol 11, p e16300 (2023)
Background Cellular senescence is an age-related physiological process that contributes to tissue dysfunction and accelerated onset of chronic metabolic diseases including hypertension. Indeed, elevation of blood pressure in hypertension coincides wi
Externí odkaz:
https://doaj.org/article/35cd5b38af0b48f09eea109507db5eb8
Autor:
Di Wang, Lingbo Liu
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 288 (2024)
Both the senescence of cancer cells and the maintenance of cancer stem cells seem to be mutually exclusive because senescence is considered a physiological mechanism that effectively suppresses tumor growth. Recent studies have revealed common signal
Externí odkaz:
https://doaj.org/article/9507c828871043a48c99d53a2eee5487
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