Zobrazeno 1 - 10
of 798
pro vyhledávání: '"self-antigen"'
Autor:
Emi Ito, Sho Yamasaki
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells that function at the interface between innate and acquired immunity. MAIT cells recognize vitamin B2-related metabolites produced by microbes, through semi-invarian
Externí odkaz:
https://doaj.org/article/36d232c4016f4adcb285cb1e29fc6fde
Publikováno v:
Drug Delivery, Vol 30, Iss 1, Pp 9-19 (2023)
AbstractRheumatoid arthritis (RA) is a systemic autoimmune disease (AD) caused by the aberrant attack of the immune system on its own joint tissues. Genetic and environmental factors are the main reasons of immune system impairment and high incidence
Externí odkaz:
https://doaj.org/article/882682a1a1d84b37a8f98bb773d675e0
Autor:
Kyogo Itoh, Satoko Matsueda
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 803 (2024)
In this comprehensive review, we explore the pivotal role of commensal Bifidobacterium (c-BIF) as potent non-self-antigens through antigenic mimicry, along with exploring the potential of humoral immune responses for both malignant and non-malignant
Externí odkaz:
https://doaj.org/article/e1518d5837c14266ae5e7e40b7fee2d3
Autor:
Robert K. Bright
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
ABSTRACTOverexpressed tumor-associated antigens (TAAs) are a large group that includes proteins found at increased levels in tumors compared to healthy cells. Universal tumor expression can be defined as overexpression in all cancers examined as has
Externí odkaz:
https://doaj.org/article/e3ae3616fe0541bb9eaa1bdea471b023
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 301-311 (2023)
We previously described therapeutic opportunities provided by capsid- and expression cassette-optimized adeno-associated virus serotype 6 (AAV6) vectors to suppress tumor growth in both solid and metastatic mouse models by using artificial ovalbumin
Externí odkaz:
https://doaj.org/article/ffff685db9bd4576be8bb6fb095a0d7b
Akademický článek
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Autor:
Fernando Chernomordik, Bojan Cercek, Jianchang Zhou, Xiaoning Zhao, Nicole Wai Man Lio, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLL-37 is the only member of the cathelicidin family of antimicrobial peptides in humans and is an autoantigen in several autoimmune diseases and in acute coronary syndrome (ACS). In this report, we profiled the specific T cell response to t
Externí odkaz:
https://doaj.org/article/05b2d9f173b040cbbb3502583f721a77
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 14-21 (2021)
Viruses have evolved to efficiently express their genes in host cells, which makes them ideally suited as gene delivery vectors for gene and immunotherapies. Replication competent (RC) viral vectors encoding foreign or self-proteins induce strong T-c
Externí odkaz:
https://doaj.org/article/7c77607ffd914eba917339b41397b390
Autor:
Chenglong Wang, Stephen R. Daley
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD4+ T cell responses to self-antigens are pivotal for immunological self-tolerance. Activation of Foxp3– T-conventional (T-conv) cells can precipitate autoimmune disease, whereas activation of Foxp3+ T-regulatory (T-reg) cells is essential to prev
Externí odkaz:
https://doaj.org/article/37031a0b0f68415e966d2fd298d08c0a
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Host-defense peptides (HDPs) are vital components of innate immunity in all vertebrates. While their antibacterial activity toward bacterial cells was the original focus for research, their ability to modulate immune and inflammatory processes has em
Externí odkaz:
https://doaj.org/article/c4910838c9ed4ec2b1cd10f4d0436409