Zobrazeno 1 - 10
of 19
pro vyhledávání: '"sefa Küçükler"'
Publikováno v:
Laboratuvar Hayvanları Bilimi ve Uygulamaları Dergisi, Vol 4, Iss 2, Pp 72-77 (2024)
Bu çalışma, fenolik asit içeren doğal bitkisel bileşik olan sinapik asidin (SA), erkek ratlarda kurşun (Pb) kaynaklı dalak toksisitesine karşı etkilerini incelemeyi amaçladı. Dalak toksisitesi, ratların 7 gün boyunca sadece Pb ya da Pb
Externí odkaz:
https://doaj.org/article/eb0685830be84e128d9e147077826b32
Publikováno v:
Scientia Pharmaceutica, Vol 85, Iss 1, p 4 (2017)
Paracetamol (PC) is a safe analgesic and antipyretic drug at therapeutic doses, and it is widely used in clinics. However, at high doses, it can induce hepatotoxicity and nephrotoxicity. Chrysin (CR) is a natural flavonoid that has biological activit
Externí odkaz:
https://doaj.org/article/7ad858c43a2541ea96c3aaeed4fc8936
Autor:
Ali Doğan ÖMÜR, Betül APAYDIN YILDIRIM, Behzad MOKHTARE, Sefa KÜÇÜKLER, Ali Sefa MENDİL, Arzu GEZER, Serkan Ali AKARSU
Publikováno v:
Veterinary Sciences and Practices, Vol 18, Iss 3, Pp 90-94 (2023)
Externí odkaz:
https://doaj.org/article/53c127c9030f4e8d85068d4729a217cc
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 9, Pp 1098-1106 (2023)
Objective(s): Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a flavonoid with many biological properties found naturally in honey and plants. This study aimed to determine the effects of ZNG on SA-induced rat lung toxicity.Mat
Externí odkaz:
https://doaj.org/article/fb7ff9a8f62147aebfce858b166bb83a
Autor:
Fazile Nur Eki̇nci̇-Akdemi̇r, Serkan Yıldırım, Fatih Mehmet Kandemir, İlhami Gülçi̇n, sefa Küçükler, Yavuz Selim Sağlam, Selvinaz Yakan
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 21, Iss 12, Pp 1281-1288 (2018)
Objective(s): In this study, we evaluated the therapeutic effects of casticin and myricetin on liver damage induced by methotrexate in rats.Materials and Methods: Thirty-six male rats were used for the study and divided into 6 groups: control, methot
Externí odkaz:
https://doaj.org/article/bab51a611af8440094aef9ce18402dd2
Autor:
Hamit Emre Kızıl, Cuneyt Caglayan, Ekrem Darendelioğlu, Adnan Ayna, Cihan Gür, Fatih Mehmet Kandemir, Sefa Küçükler
Publikováno v:
Molecular Biology Reports. 50:3479-3488
Organ toxicity limits the therapeutic efficacy of methotrexate (MTX), an anti-metabolite therapeutic that is frequently used as an anti-cancer and immunosuppressive medicine. Hepatocellular toxicity is among the most severe side effects of long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91872d9b8121bc98f9249569b8a12301
https://doi.org/10.1007/s11033-023-08286-8
https://doi.org/10.1007/s11033-023-08286-8
Autor:
Cuneyt Caglayan, Fatih Mehmet Kandemir, Adnan Ayna, Cihan Gür, Sefa Küçükler, Ekrem Darendelioğlu
Publikováno v:
Metabolic Brain Disease. 37:1931-1940
The exposure to bisphenol A (BPA) is inevitable owing to its common use in the production of polycarbonate plastics. Studies to reduce side effects are gaining importance since BPA causes severe toxicities in important tissues such as testes, lungs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98b5490f7deca27db197ddbc1722b77
https://doi.org/10.1007/s11011-022-01027-z
https://doi.org/10.1007/s11011-022-01027-z
Publikováno v:
Chemistry & Biodiversity. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59915396c24025ca1d408af019fbad24
https://doi.org/10.1002/cbdv.202200982
https://doi.org/10.1002/cbdv.202200982
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 37
Our experimental objective was to investigate the hepatotoxic effect of vincristine (VCR) administration in rats and determined whether combined therapy with Quercetin (Quer) ensured protection. Five groups with seven rats each were used for this pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9b17a47d9993bf4043c8c17a5ddf51
https://doi.org/10.1002/jbt.23326
https://doi.org/10.1002/jbt.23326
Publikováno v:
Veterinary parasitology. 314
Bovine anaplasmosis is an arthropod-borne disease characterized by high fever, anaemia and sometimes jaundice. The role of oxidative stress in anaplasmosis has been investigated, but erythrocyte arginase (ARG) activity has not been studied. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::339599980c2d2f80f4b3158e378f7592
https://pubmed.ncbi.nlm.nih.gov/36528965
https://pubmed.ncbi.nlm.nih.gov/36528965