Zobrazeno 1 - 10
of 1 589
pro vyhledávání: '"scutellarin"'
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1229-1235 (2024)
Objective To investigate the effect of scutellarin(STR) on the proliferation and migration of human prostate cancer cell line (PC-3) and its underlying mechanism. Methods PC-3 cells were divided into low-dose STR group, medium-dose STR group, high-do
Externí odkaz:
https://doaj.org/article/d5920e76b6e9452185e39d6da8044de0
Autor:
Zhao-Da Duan, Li-Yang Zheng, Qiu-Ye Jia, Hao-Lun Chen, Dong-Yao Xu, Yu-Jia Yang, Zhi Qi, Li Yang, Chun-Yun Wu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Previous studies have shown that scutellarin inhibits the excessive activation of microglia, reduces neuronal apoptosis, and exerts neuroprotective effects. However, whether scutellarin regulates activated microglia-mediated neuronal apoptos
Externí odkaz:
https://doaj.org/article/484392d96b504a778b3704c4266659c9
Autor:
Bangrui Huang, Rui Han, Hong Tan, Wenzhuo Zhu, Yang Li, Fakun Jiang, Chun Xie, Zundan Ren, Rou Shi
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Breviscapine, a natural flavonoid mixture derived from the traditional Chinese herb Erigeron breviscapus (Vant.) Hand-Mazz, has demonstrated a promising potential in improving diabetic nephropathy (DN). However, the specific active constitue
Externí odkaz:
https://doaj.org/article/79bc4a1b4efa4b05883696bbfa1809f6
Autor:
Yang Zhou, Chenlin Gu, Yan Zhu, Yuting Zhu, Yutong Chen, Li Shi, Yang Yang, Xin Lu, Hanqing Pang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Inflammation is a biological response of multicellular organisms caused by injuries, pathogens or irritants. An excessive inflammatory response can lead to tissue damage and various chronic diseases. Chronic inflammation is a common feature of many d
Externí odkaz:
https://doaj.org/article/042fd4b3fa124aa790bd089f7d86b17e
Publikováno v:
Natural Products and Bioprospecting, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Scutellarin is widely distributed in Scutellaria baicalensis, family Labiatae, and Calendula officinalis, family Asteraceae, and belongs to flavonoids. Scutellarin has a wide range of pharmacological activities, it is widely used in the trea
Externí odkaz:
https://doaj.org/article/50030f1382ea45b7983c74421e1bfe50
Publikováno v:
Shipin gongye ke-ji, Vol 45, Iss 5, Pp 331-340 (2024)
To detect the effect of scutellarin (SCU) on promoting the sensitivity of breast cancer 4T1 cells to cisplatin (CDDP), and the molecular mechanism as well. CCK-8, scratch assay, Transwell assay and flow cytometry were employed to investigate the effe
Externí odkaz:
https://doaj.org/article/853e6ddbe9a24be6b1f1568529c6c1bc
Autor:
Fang Cheng, Jie Zhang, Pan Yang, Zufei Chen, Yinghao Fu, Jiajia Mi, Xingliang Xie, Sha Liu, Yanmei Sheng
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29162- (2024)
Chronic cerebral ischemia (CCI) primarily causes cognitive dysfunction and other neurological impairments, yet there remains a lack of ideal therapeutic medications. The preparation combination of Astragalus membranaceus (Fisch.) Bunge and Erigeron b
Externí odkaz:
https://doaj.org/article/1dbe31456e774beb8340c0645fe393a6
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Cardiovascular diseases represent a significant worldwide problem, jeopardizing individuals’ physical and mental wellbeing as well as their quality of life as a result of their widespread incidence and fatality. With the aging society, the occurren
Externí odkaz:
https://doaj.org/article/e8c02f671bcd45e79924ce09880ba80a
Publikováno v:
Shipin gongye ke-ji, Vol 44, Iss 17, Pp 406-412 (2023)
The aim of the present study was to clarify the pathway and mechanism involved in the anti-melanona effect of Scutellarin (SCU). CCK-8 and Transwell assays were employed to evaluate the cell proliferation and migratory abilities of B16 in vitro. Then
Externí odkaz:
https://doaj.org/article/c29599070130448b87356d5032be2a30
Autor:
Ning Sheng, Zhihui Zhang, Hao Zheng, Congyu Ma, Menglin Li, Zhe Wang, Lulu Wang, Jiandong Jiang, Jinlan Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Mitochondrial bioenergetic deficits and their resulting glucose hypometabolism are the key pathophysiological modulators that promote neurodegeneration. However, there are no specific potential molecules that have been identified to treat ne
Externí odkaz:
https://doaj.org/article/fd001e5c45ed410396fe1757e32eb553