Zobrazeno 1 - 10
of 6 033
pro vyhledávání: '"scfv"'
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-27 (2024)
Abstract Immunotherapy has transformed the landscape of cancer treatment, with chimeric antigen receptor (CAR)-engineered T (CAR-T) cell therapy emerging as a front runner in addressing some hematological malignancies. Despite its considerable effica
Externí odkaz:
https://doaj.org/article/4442d43ba4af488c81033163b80f83cb
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 300-308 (2024)
Lung cancer is a dangerous disease that is lacking in an ideal therapy. Here, we evaluated the anti-lung cancer effect in nude mice of a fully human single-chain antibody (scFv) against the associated antigen 7 transmembrane receptor (Ts7TMR), which
Externí odkaz:
https://doaj.org/article/ae2aabe187b741fe8409b557bab6839b
Autor:
Nattha Ingavat, Nuruljannah Dzulkiflie, Jia Min Liew, Xinhui Wang, Eunice Leong, Han Ping Loh, Say Kong Ng, Yuansheng Yang, Wei Zhang
Publikováno v:
Bioresources and Bioprocessing, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract Bispecific antibodies (bsAbs) hold promises for enhanced therapeutic potential surpassing that of their parental monoclonal antibodies. However, bsAbs pose great challenges in their manufacturing, and one of the common reasons is their susce
Externí odkaz:
https://doaj.org/article/aec2e4f2fb0a469f8e69c7c502893e55
Autor:
Hancong Sun, Lingyun Xia, Jianhua Li, Yuanyuan Zhang, Guanying Zhang, Ping Huang, Xingxing Wang, Yue Cui, Ting Fang, Pengfei Fan, Qiang Zhou, Xiangyang Chi, Changming Yu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
SARS-CoV-2 has been evolving into a large number of variants, including the highly pathogenic Delta variant, and the currently prevalent Omicron subvariants with extensive evasion capability, which raises an urgent need to develop new broad-spectrum
Externí odkaz:
https://doaj.org/article/1d674d777c2e49439ecdb7cb2d869d63
Autor:
Beom Jun Kwon, Na Hyun Cho, Taeyoung Ahn, Geunah Kim, Nguyễn Thị Xuân Diệu, Woo Taek Kim, Hyung-Ju Cho, Dong Hye Seo, Joo Young Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Plants offer a cost-effective and scalable pharmaceutical platform devoid of host-derived contamination risks. However, their medical application is complicated by the potential for acute allergic reactions to external proteins. Developing p
Externí odkaz:
https://doaj.org/article/511d5664a0bf456e8362af26456beb85
Autor:
Yanzi Sun, Yishu Wang, Chunyan Liu, Yingshuang Huang, Qiulin Long, Caoyun Ju, Can Zhang, Yijun Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Tyrosine kinase inhibitors have been the standard treatment for patients with Philadelphia chromosome-positive (Ph+) leukemia. However, a series of issues, including drug resistance, relapse and intolerance, are still an unmet medical need.
Externí odkaz:
https://doaj.org/article/ab03536952134cfcbd34ade302bbd69c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Sophia K. Berry, Steven Rust, Lorraine Irving, Josefin Bartholdson Scott, Lucy A. Weinert, Gordon Dougan, Graham Christie, Paul Warrener, Ralph Minter, Andrew J. Grant
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT We used phage display, antibody engineering, and high-throughput assays to identify antibody-accessible targets of Klebsiella pneumoniae. We report the discovery of monoclonal antibodies (mAbs) binding to type 3 fimbrial proteins, including
Externí odkaz:
https://doaj.org/article/95aa0fb605154b428c64e9bc9b28abc5