Bromopyrrole Alkaloids from the Sponge Agelas kosrae

Autor: Oh-Seok Kwon, Donghwa Kim, Heegyu Kim, Yeon-Ju Lee, Hyi-Seung Lee, Chung J. Sim, Dong-Chan Oh, Sang Kook Lee, Ki-Bong Oh, Jongheon Shin

Publikováno v: Marine Drugs, Vol 16, Iss 12, p 513 (2018)

Two new sceptrin derivatives (1,2) and eight structurally-related known bromopyrrole-bearing alkaloids were isolated from the tropical sponge Agelas kosrae. By a combination of spectroscopic methods, the new compounds, designated dioxysceptrin (1) an

Externí odkaz: https://doaj.org/article/c971386e0d814435addacb404a4c54e6

Structure- and Ligand-Based in silico Studies towards the Repurposing of Marine Bioactive Compounds to Target SARS-CoV-2

Autor: Yaseen A.M.M. Elshaier, Ahmed Mostafa, Khaled A.M. Abouzid, Inas A. Abdallah, Hanan Elimam, Hend Mohamed Abdel-Bar, Marwa A. A. Fayed, Yassmin Moatasim, Mohammed Farrag El-Behairy

Publikováno v: Arabian Journal of Chemistry, Vol 14, Iss 4, Pp 103092-(2021)
Arabian Journal of Chemistry

Graphical abstract
This work was a structured virtual screening for marine bioactive compounds with reported antiviral activities which were subjected to structure-based studies against SARS-CoV-2 co-crystallized proteins. The molecular docking

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f6b80acd157bf00840b8c895d2556e
http://www.sciencedirect.com/science/article/pii/S1878535221001076

In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa

Autor: Juan C. Vázquez-Ucha, Jaime Rodríguez, Alejandro Beceiro, Marta Martínez-Guitián, Germán Bou, Cristina Lasarte-Monterrubio, Mar Pérez-Povedano, Carlos Jiménez, Dawrin Pech-Puch

Publikováno v: RUC. Repositorio da Universidade da Coruña
Universitat Oberta de Catalunya (UOC)
Marine Drugs
Volume 18
Issue 6
Marine Drugs, Vol 18, Iss 326, p 326 (2020)
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)

The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the secondary metabolites of the sponge A. dilat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef261fcfc19d0fbb8fb1a5481e57d70
http://hdl.handle.net/2183/25903

Bromopyrrole Alkaloids from the Sponge Agelas kosrae

Autor: Jongheon Shin, Yeon-Ju Lee, Hyi-Seung Lee, Oh Seok Kwon, Sang Kook Lee, Heegyu Kim, Donghwa Kim, Ki-Bong Oh, Chung J. Sim, Dong-Chan Oh

Publikováno v: Marine Drugs, Vol 16, Iss 12, p 513 (2018)
Marine Drugs
Volume 16
Issue 12

Two new sceptrin derivatives (1,2) and eight structurally-related known bromopyrrole-bearing alkaloids were isolated from the tropical sponge Agelas kosrae. By a combination of spectroscopic methods, the new compounds, designated dioxysceptrin (1) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5030201721fc3c34a13c9f80ec3cb0
https://www.mdpi.com/1660-3397/16/12/513

Sceptrin - Enantioselective Synthesis of a Tetrasubstituted all-trans Cyclobutane Key Intermediate

Autor: Lena Barra, Jeroen S. Dickschat

Publikováno v: European Journal of Organic Chemistry. 2017:4566-4571

The asymmetric synthesis of both enantiomers of tetrasubstituted all-trans dimethyl 3,4-diacetylcyclobutane-1,2-dicarboxylate with high enantiomeric purity (>98 % ee) using a valine-derived chiral auxiliary in a diastereoselective photodimerization i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b92ddb14678255daa08d4012e68ef8e3
https://doi.org/10.1002/ejoc.201700882