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Akademický článek

Soluble CD206 and CD163 as novel prognostic biomarkers in adult acute myeloid leukemia

Autor: Haifa A. Al-Matari, Anwar B. Mansour, Sherif Abdelaziz Ibrahim, Nadia El-Sayed Zaki, Abeer Mahmoud Badr

Publikováno v: Journal of Basic and Applied Zoology, Vol 85, Iss 1, Pp 1-10 (2024)

Abstract Background Despite advances in chemotherapy, the prognosis of adult acute myeloid leukemia (AML) patients remains poor, with a 5-year survival rate below 25%. In the tumor microenvironment of AML, tumor-associated macrophages (TAMs) are very

Externí odkaz: https://doaj.org/article/d07207d1ca354fc8bceba20093ac20f5

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Akademický článek

Peripheral immune signatures associated with the risk of hepatocarcinogenesis in cirrhotic Egyptian HCV patients before and after treatment with direct-acting antivirals

Autor: Reem El-Shenawy, Rehab I. Moustafa, Naiera M. Helmy, Yasmine S. El-Abd, Ashraf A. Tabll, Yasser K. Elesnawy, Heba Shawky

Publikováno v: Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)

Abstract Background Although direct-acting antivirals (DAAs) have revolutionized the management of chronic HCV, the debatable association with hepatocellular carcinoma (HCC) occurrence/recurrence has raised major concerns about their long-term use, e

Externí odkaz: https://doaj.org/article/8198a63724804936a9c6a5b07794cc9f

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Akademický článek

The Role of Soluble CD163 (sCD163) in Human Physiology and Pathophysiology

Autor: Andriana Plevriti, Margarita Lamprou, Eleni Mourkogianni, Nikolaos Skoulas, Maria Giannakopoulou, Md Sanaullah Sajib, Zhiyong Wang, George Mattheolabakis, Antonios Chatzigeorgiou, Antonia Marazioti, Constantinos M. Mikelis

Publikováno v: Cells, Vol 13, Iss 20, p 1679 (2024)

Soluble CD163 (sCD163) is a circulating inflammatory mediator, indicative of acute and chronic, systemic and non-systemic inflammatory conditions. It is the cleavage outcome, consisting of almost the entire extracellular domain, of the CD163, a recep

Externí odkaz: https://doaj.org/article/dec86798af9b4cd6a3042764451dc486

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Akademický článek

Association of Circulating Markers of Microbial Translocation and Hepatic Inflammation with Liver Injury in Patients with Type 2 Diabetes

Autor: Leila Gobejishvili, Vatsalya Vatsalya, Diana V. Avila, Yana B. Feygin, Craig J. McClain, Sriprakash Mokshagundam, Shirish Barve

Publikováno v: Biomedicines, Vol 12, Iss 6, p 1227 (2024)

Background: Virtually the entire spectrum of liver disease is observed in association with type 2 diabetes mellitus (T2DM); indeed, T2DM is now the most common cause of liver disease in the U.S. We conducted a pilot study to investigate the relevance

Externí odkaz: https://doaj.org/article/c61f484e543b4433bd2cec561bb67713

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Akademický článek

Biomarkers of cell damage, neutrophil and macrophage activation associated with in-hospital mortality in geriatric COVID-19 patients

Publikováno v: Immunity & Ageing, Vol 19, Iss 1, Pp 1-14 (2022)

Abstract Background The risk for symptomatic COVID-19 requiring hospitalization is higher in the older population. The course of the disease in hospitalised older patients may show significant variation, from mild to severe illness, ultimately leadin

Externí odkaz: https://doaj.org/article/a7dee6b0d59b47a48fee8509a4cbdf94

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Akademický článek

PRELIMINARY STUDY OF SCD14 AND SCD163 AS PREDICTORS OF DISEASE SEVERITY AND ICU ADMISSION IN COVID-19: RELATION TO HEMATOLOGICAL PARAMETERS, BLOOD MORPHOLOGICAL CHANGES AND INFLAMMATORY BIOMARKERS

Autor: hend Attia

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2023)

Abstract.Background and Objectives: Research supports the role of monocyte/macrophage activation in COVID-19 immunopathology. This study aimed to evaluate sCD14 and sCD163 -the monocyte activation markers -and to investigate their relation to hematol

Externí odkaz: https://doaj.org/article/7aa9a537001949768d8491632555209b

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Akademický článek

Expression profile of microRNAs related with viral infectivity, inflammatory response, and immune activation in people living with HIV

Autor: Sara Cuesta-Sancho, Denisse Márquez-Ruiz, Francisco Illanes-Álvarez, Irene Campaña-Gómez, Andrés Martín-Aspas, María Teresa Trujillo-Soto, Alberto Romero, Fátima Galán, Manuel Rodríguez-Iglesias, Mercedes Márquez-Coello, José-Antonio Girón-González

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

ObjectiveTo evaluate the serum expression of microRNAs (miRNAs) with ability to modulate the human immunodeficiency (HIV) replication or inflammatory status in people living with HIV (PLWH).MethodsForty healthy controls and two groups of PLWH were ev

Externí odkaz: https://doaj.org/article/60e5cea1aca246cfb13594d27b2088e6

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Akademický článek

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