Zobrazeno 1 - 10
of 126
pro vyhledávání: '"scandium-44"'
Autor:
Nadia Benabdallah, Hanwen Zhang, Ryan Unnerstall, Amanda Fears, Lucy Summer, Michael Fassbender, Buck E. Rodgers, Diane Abou, Valery Radchenko, Daniel L. J. Thorek
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Background 44Sc/47Sc is an attractive theranostic pair for targeted in vivo positron emission tomographic (PET) imaging and beta-particle treatment of cancer. The 44Ti/44Sc generator allows daily onsite production of this diagnostic isotope,
Externí odkaz:
https://doaj.org/article/0b81433194ff4a17b78c6f359d2e1aa6
Autor:
Jean-Philippe Sinnes, Ulrike Bauder-Wüst, Martin Schäfer, Euy Sung Moon, Klaus Kopka, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Background The AAZTA chelator and in particular its bifunctional derivative AAZTA5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study pre
Externí odkaz:
https://doaj.org/article/d1a2d3b0fd9c4b479ae97266b454021c
Autor:
Florian Rosar, Hans-Georg Buchholz, Sebastian Michels, Manuela A. Hoffmann, Markus Piel, Christopher M. Waldmann, Frank Rösch, Stefan Reuss, Mathias Schreckenberger
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-17 (2020)
Abstract Background 44Sc has been increasingly investigated as a potential alternative to 68Ga in the development of tracers for positron emission tomography (PET). The lower mean positron energy of 44Sc (0.63 MeV) compared to 68Ga (0.83 MeV) can res
Externí odkaz:
https://doaj.org/article/c7f7458b7f394c2cb0b0c2c49ca6420c
Akademický článek
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Autor:
Dahl, Jon Kristian
Publikováno v:
Dahl, Jon Kristian. Investigating the low energy enhancement of \(^{44}\)Sc, \(^{50,51}\)V and \(^{64}\)Zn with large-scale shell model calculations. Master thesis, University of Oslo, 2022
Externí odkaz:
http://hdl.handle.net/10852/98432
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-10 (2019)
Abstract Purpose AAZTA (1,4-bis (carboxymethyl)-6-[bis (carboxymethyl)]amino-6-methylperhydro-1,4-diazepine) based chelators were initially developed in the context of magnetic resonance imaging. First radiochemical studies showed the capability of A
Externí odkaz:
https://doaj.org/article/5c3750d7fc0b4121bfa8fc4812a25e44
Autor:
Patricia E. Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Abdolreza Yazdani, Matthias Miederer, Andreas Kjær, John F. Valliant, Marc S. Robillard, Frank Rösch, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have bee
Externí odkaz:
https://doaj.org/article/3c3a2b2c7f3b4c0690ccc0893c5a719d
Autor:
Dániel Szücs, Tibor Csupász, Judit P. Szabó, Adrienn Kis, Barbara Gyuricza, Viktória Arató, Viktória Forgács, Adrienn Vágner, Gábor Nagy, Ildikó Garai, Dezső Szikra, Imre Tóth, György Trencsényi, Gyula Tircsó, Anikó Fekete
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 666 (2022)
Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission tomography (PET) enables the detection of the hypoxic regions in tumors using 2-nitroimida
Externí odkaz:
https://doaj.org/article/843f4628244a414b8a57736cdc4ebaed
Autor:
Elisabeth Eppard, Ana de la Fuente, Nicole Mohr, Mareli Allmeroth, Rudolf Zentel, Matthias Miederer, Stefanie Pektor, Frank Rösch
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Background In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure t
Externí odkaz:
https://doaj.org/article/d2fa3e625d174a858aa6f3bfbe074e77
Publikováno v:
Molecules, Vol 26, Iss 21, p 6371 (2021)
Today, 44Sc is an attractive radionuclide for molecular imaging with PET. In this work, we evaluated a 44Ti/44Sc radionuclide generator based on TEVA resin as a source of 44Sc. The generator prototype (5 MBq) exhibits high 44Ti retention and stable y
Externí odkaz:
https://doaj.org/article/bf32eed5bc3b4b8ebcd625f050e7f4b7