Zobrazeno 1 - 10
of 182
pro vyhledávání: '"scRNA-sequencing"'
Autor:
Junhui Chen, Qian Zhang, Jinan Guo, Di Gu, Jing Liu, Piao Luo, Yunmeng Bai, Jiayun Chen, Xinzhou Zhang, Sheng Nie, Chunbo Chen, Yulin Feng, Jigang Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1661-1676 (2024)
Diabetic nephropathy (DN) is a severe complication of diabetes, characterized by changes in kidney structure and function. The natural product rosmarinic acid (RA) has demonstrated therapeutic effects, including anti-inflammation and anti-oxidative-s
Externí odkaz:
https://doaj.org/article/9349afe6eec94cf19d136da295d6b5b0
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27379- (2024)
Background: Cuproptosis is a copper-dependent cell death that is connected to the development and immune response of multiple diseases. However, the function of cuproptosis in the immune characteristics of sepsis remains unclear. Method: We obtained
Externí odkaz:
https://doaj.org/article/5f1efcb4c0d4499cb18bb6306b2a493b
Autor:
Ha-Young Kim, Clémentine Charton, Jung Hee Shim, So Young Lim, Jinho Kim, Sejoon Lee, Jung Hun Ohn, Baek Kyu Kim, Chan Yeong Heo
Publikováno v:
Cells, Vol 13, Iss 9, p 729 (2024)
Fibrous dysplasia (FD) is a rare bone disorder characterized by the replacement of normal bone with benign fibro-osseous tissue. Developments in our understanding of the pathophysiology and treatment options are impeded by the lack of suitable resear
Externí odkaz:
https://doaj.org/article/48ec638a6cea42e3998ae9552601927c
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Marc Corrales, Benjamin T. Cocanougher, Andrea B. Kohn, Jason D. Wittenbach, Xi S. Long, Andrew Lemire, Albert Cardona, Robert H. Singer, Leonid L. Moroz, Marta Zlatic
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-23 (2022)
Abstract Molecular profiles of neurons influence neural development and function but bridging the gap between genes, circuits, and behavior has been very difficult. Here we used single cell RNAseq to generate a complete gene expression atlas of the D
Externí odkaz:
https://doaj.org/article/8da66f866b114055b6916e18666e7aca
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2606-2614 (2022)
Two of the most common neurodegenerative disorders – Alzheimer’s and Parkinson’s diseases – are characterized by synaptic dysfunction and degeneration that culminate in neuronal loss due to abnormal protein accumulation. The intracellular agg
Externí odkaz:
https://doaj.org/article/9d407ef1ed834b699fc63e1c81c9b3e8
Autor:
Tai Lai Zhou, Heng Xin Chen, Yin Zhao Wang, Si Jie Wen, Ping Hong Dao, Yu Hang Wang, Min Feng Chen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCystitis glandularis (CG) is a rare chronic bladder hyperplastic disease that mainly manifests by recurrent frequent urination, dysuria and gross hematuria. The current lack of unified diagnosis and treatment criteria makes it essential t
Externí odkaz:
https://doaj.org/article/689cfb5007814152869f716089ed67f1
Autor:
Filippos T. Charitidis, Elham Adabi, Frederic B. Thalheimer, Colin Clarke, Christian J. Buchholz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 359-369 (2021)
Quantifying gene expression in individual cells can substantially improve our understanding about complex genetically engineered cell products such as chimeric antigen receptor (CAR) T cells. Here we designed a single-cell RNA sequencing (scRNA-seq)
Externí odkaz:
https://doaj.org/article/1ddaed49aea24261abd1f8f44017b01a