Zobrazeno 1 - 10
of 7 304
pro vyhledávání: '"scRNA-seq"'
Autor:
Yuan‐Ping Yang, Zhi‐Guang Huang, Jia‐Yuan Luo, Juan He, Lin Shi, Gang Chen, Si‐Yuan Chen, Yu‐Wen Deng, Yi‐Jia Yang, Yi‐Jun Tang, Yu‐Yan Pang
Publikováno v:
IET Systems Biology, Vol 18, Iss 5, Pp 183-198 (2024)
Abstract Synaptojanin 2 (SYNJ2) has crucial role in various tumors, but its role in papillary thyroid carcinoma (PTC) remains unexplored. This study first detected SYNJ2 protein expression in PTC using immunohistochemistry method and further assessed
Externí odkaz:
https://doaj.org/article/8ff252af1f3e40c39bfc48dacd0ab758
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Chronic Kidney Disease (CKD) impacts over 10% of the global population, and recent advancements in high-throughput analytical technologies are uncovering the complex physiology underlying this condition. By integrating Genome-Wide
Externí odkaz:
https://doaj.org/article/5083b0b1478d4a6692d5aff5939cec96
Autor:
Sofiia Baranykova, Rishikesh Kumar Gupta, Arkadiusz Kajdasz, Iga Wasilewska, Matylda Macias, Aleksandra Szybinska, Tomasz Węgierski, Karim Abu Nahia, Shamba S. Mondal, Cecilia L. Winata, Jacek Kuźnicki, Lukasz Majewski
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Calcium is involved in vision processes in the retina and implicated in various pathologies, including glaucoma. Rod cells rely on store-operated calcium entry (SOCE) to safeguard against the prolonged lowering of intracellular calcium ion c
Externí odkaz:
https://doaj.org/article/ef3c06b4afc24f27a586cb85f8a34536
Autor:
Hao Jiang, Biao Gao, Zihe Meng, Yafei Wang, Tianyu Jiao, Junfeng Li, Xuerui Li, Yinbiao Cao, Xianzhou Zhang, Chonghui Li, Shichun Lu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract This study aims to investigate the interplay between tumor-associated endothelial cells (TECs) and immune cells within the tumor microenvironment (TME) and its impact on tumor prognosis. We conducted single-cell RNA sequencing (scRNA-seq) of
Externí odkaz:
https://doaj.org/article/e6a5f4bd94c440f2b92902d421d1c35c
Autor:
Nan Zhao, Xiawei Ding, CaiHuan Tian, Shixin Wang, Shuyan Xie, Hongda Zou, Hao Liu, Jingyi Chen, Xue lian Liang, Lifei Huang
Publikováno v:
BMC Plant Biology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Single-cell transcriptome sequencing (scRNA-seq) is a powerful tool for describing the transcriptome dynamics of plant development but has not yet been utilized to analyze the tissue ontology of sweetpotato. This study established a stable m
Externí odkaz:
https://doaj.org/article/aac27df3cb2c424ea885de3b2378922f
Autor:
Leiting Shen, Chang Tao, Kun Zhu, Linghao Cai, Sisi Yang, Jingyi Jin, Yichao Ren, Yi Xiao, Yuebai Zhang, Dengming Lai, Jinfa Tou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Sepsis is a life-threatening organ malfunction induced by an imbalanced immunological reaction to infection in the host. Many studies have utilized traditional RNA sequencing (RNA-seq) data to identify important biological targets to predict
Externí odkaz:
https://doaj.org/article/07f926e2bbe74583ae54be31eaab8c37
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Increasingly, scRNA-Seq studies explore cell populations across different samples and the effect of sample heterogeneity on organism’s phenotype. However, relatively few bioinformatic methods have been developed which adequately address th
Externí odkaz:
https://doaj.org/article/63f57038731f451190d9327b3cc02021
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Prostate cancer (PCa) usually manifests atypical symptoms in the early stage, and once symptoms appear, most PCa patients have developed to the advanced stage, failing to undergo radical surgery. In this study, PCa occurrence-rela
Externí odkaz:
https://doaj.org/article/31fee4ef354a4eb388e9e2224bf08b04
Autor:
Yujing Sun, Zhenhua Zhang, Qincheng Qiao, Ying Zou, Lina Wang, Tixiao Wang, Bo Lou, Guosheng Li, Miao Xu, Yanxiang Wang, Zhenhong Zhang, Xinguo Hou, Li Chen, Ruxing Zhao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral b
Externí odkaz:
https://doaj.org/article/8ea964cfb0db40a2882660eb63ef2a0b
Autor:
Zheng Xie, Huicong Xie, Chen Xie, Saichao Yang, Yun Feng, Zhaohai Su, Tao Tang, Bilong Zhang, Jiangyong Yang, Yueting Wang, Ling Huang, Hengqing Zhu, Jun Cao, Rengui Jiang, Tian Li, Weiling Lu
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Myocardial infarction (MI) induces complex transcriptional changes across diverse cardiac cell types. Single-cell RNA sequencing (scRNA-seq) provides an unparalleled ability to discern cellular diversity during infarction, yet the
Externí odkaz:
https://doaj.org/article/85c42e3cd79e4ce18f39c3141d227159