Zobrazeno 1 - 10
of 7 383
pro vyhledávání: '"scRNA seq"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The liver is the predominant metastatic site for diverse cancers, including pancreatic and colorectal cancers (CRC), etc. The high incidence of hepatic metastasis of pancreatic cancer is an important reason for its refractory and high mortal
Externí odkaz:
https://doaj.org/article/a49c784b2c054e1c8f2ed29975d408e8
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Cutaneous malignant melanoma is a very aggressive and metastatic form of skin cancer, typically linked with poor outcomes. Advances in genomic analysis have underscored the crucial role of T cells in tumor immunity. Immune checkpo
Externí odkaz:
https://doaj.org/article/516c48cfffdd43a4843ee3baf6e4e692
Autor:
Lin W, Tang L, Zhuo C, Mao X, Shen J, Huang S, Li S, Qin Y, Liao J, Chen Y, Zhang X, Li Y, Song J, Meng L, Dong X
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 11, Pp 2269-2281 (2024)
Wenxian Lin,1– 4 Lizhu Tang,1,2,5 Chenyi Zhuo,1 Xiuli Mao,1– 4 Jiajia Shen,6 Shaoang Huang,3 Shangyang Li,3,7 Yujuan Qin,3,4 Ju Liao,2,3 Yuhong Chen,8 Xiamin Zhang,3,4 Yuting Li,9 Jian Song,4 Lingzhang Meng,4 Xiaofeng Dong,10 Yueyong Li2 1Key Lab
Externí odkaz:
https://doaj.org/article/4af90f981bf64a11896c64eafac51563
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Single-cell RNA sequencing experiments commonly use 10x Genomics (10x) kits due to their high-throughput capacity and standardized protocols. Recently, Parse Biosciences (Parse) introduced an alternative technology that uses multi
Externí odkaz:
https://doaj.org/article/aac5f50fc29348b5bb61a38fddfc938e
Autor:
Yukang Wu, Jianguo Li, Ke Feng, Ailing Tan, Yingying Gao, Wen Chen, Wenwen Jia, Xudong Guo, Jiuhong Kang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background The efficiency of mesenchymal stem cells (MSCs) in treating myocardial infarction (MI) remains inconsistent, which limits their therapeutic applications. Therefore, exploring the mechanism for the inconsistent efficacy of MSCs and
Externí odkaz:
https://doaj.org/article/4a70f36ef68d4e36ad55ae573854c4f7
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Aim The present work set out to classify cell subpopulations related to liver metastasis from gastric cancer (GC) and the mechanisms of their interactions with other immune cell subpopulations. Background GC is characterized by a high degree
Externí odkaz:
https://doaj.org/article/5f631c69ed794348a23ee487a2a92c20
Autor:
Haruki Watanabe, Minakshi Rana, Myoungsun Son, Pui Yan Chiu, Yurong Fei-Bloom, Kwangmin Choi, Betty Diamond, Barbara Sherry
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-22 (2024)
Abstract Background Sepsis survivors exhibit immune dysregulation that contributes to poor long-term outcomes. Phenotypic and functional alterations within the myeloid compartment are believed to be a contributing factor. Here we dissect the cellular
Externí odkaz:
https://doaj.org/article/cd20bcf3fc7f4dae8d46999c17da69b2
Autor:
Yang Li, Pengjie Shi, Yuhong Ding, Zhipeng Yao, Lilong Liu, Junyi Hu, Zhenghao Liu, Jinxu Li, Ke Chen, Yaxin Hou
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Bladder cancer (BC) is a prevalent malignancy characterized by significant cellular heterogeneity. While single-cell multi-omics studies have provided valuable insights, much of the existing data remains underexplored, limiting ou
Externí odkaz:
https://doaj.org/article/4a12862f16d64245a162b5872f153f5e
Autor:
Yanli Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. The prognosis of AML can be challenging, emphasizing the need for ongoing research and innovative approaches to improve outcomes in individuals affected by this f
Externí odkaz:
https://doaj.org/article/3f36152e90d5401baf343ca61d03a79a
Autor:
Hyunmin Koo, Casey D. Morrow
Publikováno v:
Retrovirology, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Since previous studies have suggested that the RNAs of human endogenous retrovirus (HERV) might be involved in regulating innate immunity, it is important to investigate the HERV transcriptome patterns in innate immune cell types such as CD1
Externí odkaz:
https://doaj.org/article/74773dd8fc2d4583b73fbb8d10ed6655