Zobrazeno 1 - 10
of 143
pro vyhledávání: '"scFv antibodies"'
Autor:
Kristian Daniel Ralph Roth, Esther Veronika Wenzel, Maximilian Ruschig, Stephan Steinke, Nora Langreder, Philip Alexander Heine, Kai-Thomas Schneider, Rico Ballmann, Viola Fühner, Philipp Kuhn, Thomas Schirrmann, André Frenzel, Stefan Dübel, Maren Schubert, Gustavo Marçal Schmidt Garcia Moreira, Federico Bertoglio, Giulio Russo, Michael Hust
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Antibodies are essential molecules for diagnosis and treatment of diseases caused by pathogens and their toxins. Antibodies were integrated in our medical repertoire against infectious diseases more than hundred years ago by using animal sera to trea
Externí odkaz:
https://doaj.org/article/a209cfb24a6a400db098fc0eff68beaa
Publikováno v:
Biotechnologia Acta, Vol 10, Iss 5, Pp 19-29 (2017)
Obtaining single-chain variable fragments (scFv) of recombinant antibodies in E. coli cells is often associated with numerous problems causing low yields or inactive conformation of the product. The aim of this work was to study the influence of s
Externí odkaz:
https://doaj.org/article/28e83e895cee47bcbecc86471798d428
Publikováno v:
Molecular Immunology
As the second wave of COVID-19 launched, various variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have emerged with a dramatic global spread amongst millions of people causing unprecedented case fatalities and economic shut-do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4187c62f4fb9483cc4672127c1d075a
https://doi.org/10.1016/j.molimm.2021.12.006
https://doi.org/10.1016/j.molimm.2021.12.006
Autor:
O. S. Oliinyk, K. O. Palyvoda, N. E. Lugovskaya, D. V. Kolibo, E. V. Lugovskoy, S. V. Komisarenko
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 2, Pp 88-94 (2015)
The aim of this work was to obtain the recombinant single chain variable fragments of antibodies (scFv) against human protein C, the key component of blood anticoagulation system. For this purpose a peptide that mimics a Pro144-Leu155 sequence of pro
Externí odkaz:
https://doaj.org/article/8a64481f15b64b70b60b1c9f8e719186
Autor:
Ginka Nikolova, Gabriela Radulova, Alexandra Atanasova, Ivanka Tsacheva, Yana Georgieva, Alexandra Kapogianni
Publikováno v:
Molecular Biotechnology. 63:1049-1056
The monoclonal antibodies and the recombinant antibody fragments are widely used in the biotechnology studies and in medicine as a powerful therapeutic and diagnostic tool. The most commonly used recombinant antibody fragments are single-chain fragme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a05da4e54e496c7bea42121f8e46cbb
https://doi.org/10.1007/s12033-021-00363-2
https://doi.org/10.1007/s12033-021-00363-2
Publikováno v:
Biotechnologia Acta, Vol 7, Iss 1, Pp 54-59 (2014)
Diphtheria toxin is an exoantigen of Corynebacterium diphtheriae that inhibits protein synthesis and kills sensitive cells. The aim of this study was to obtain human recombinant single-chain variable fragment (scFv) antibodies against receptor-bindin
Externí odkaz:
https://doaj.org/article/175d5e712c0440e880ce7f30206573b6
Autor:
Wiwat Pattanawong, Surat Hongsibsong, Korawan Sringarm, Supamit Mekchay, Wannaluk Thaworn, Marninphan Thongkham
Publikováno v:
Animal Biotechnology. 33:508-518
Distinguishing between bull Y- and X-bearing sperm populations is advantageous for techniques using sexed bull semen. The aim of this study was to produce a single-chain fragment variable (scFv) antibody against plasma membrane epitopes on bull Y-bea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5588bdb834801c5a793e88a326b11ea
https://doi.org/10.1080/10495398.2020.1811294
https://doi.org/10.1080/10495398.2020.1811294
Autor:
K. Manoutcharian, G. Acero, M.E. Munguia, B. Becerril, L. Massieu, T. Govezensky, E. Ortiz, J.D. Marks, C. Cao, K. Ugen, G. Gevorkian
Publikováno v:
Neurobiology of Disease, Vol 17, Iss 1, Pp 114-121 (2004)
A library of phage-displayed human single-chain Fv (scFv) antibodies was selected against the human amyloid-beta peptide (Aβ42). Two new anti-Aβ42 phage-displayed scFvs antibodies were obtained, and the sequences of their VH and Vκ genes were anal
Externí odkaz:
https://doaj.org/article/fb186f211e954734946ee9c83a78a829
Autor:
Maureen Gatherer, Andrew J. Lotery, Jennifer Scott, Robert E MacLaren, Michelle E. McClements, Chris Hughes, Martin J. Glennie, Neil M.J. O’Flynn, S. V. Goverdhan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 86-98 (2019)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
While anti-angiogenic therapies for wet age-related macular degeneration (AMD) are effective for many patients, they require multiple injections and are expensive and prone to complications. Gene therapy could be an elegant solution for this problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a797f2015439cc6e1d403466e2f267fd
https://doi.org/10.1016/j.omtm.2018.11.005
https://doi.org/10.1016/j.omtm.2018.11.005
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