Zobrazeno 1 - 10
of 351
pro vyhledávání: '"scATAC-seq"'
Autor:
Yu Zhao, Zheng-Min Yu, Ting Cui, Li-Dong Li, Yan-Yu Li, Feng-Cui Qian, Li-Wei Zhou, Ye Li, Qiao-Li Fang, Xue-Mei Huang, Qin-Yi Zhang, Fu-Hong Cai, Fu-Juan Dong, De-Si Shang, Chun-Quan Li, Qiu-Yu Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2746-2753 (2024)
The advent of single cell transposase-accessible chromatin sequencing (scATAC-seq) technology enables us to explore the genomic characteristics and chromatin accessibility of blood cells at the single-cell level. To fully make sense of the roles and
Externí odkaz:
https://doaj.org/article/442ac454a734428abf1a60c3dd4e27cf
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-30 (2024)
Abstract Background Single-cell chromatin accessibility assays, such as scATAC-seq, are increasingly employed in individual and joint multi-omic profiling of single cells. As the accumulation of scATAC-seq and multi-omics datasets continue, challenge
Externí odkaz:
https://doaj.org/article/e3f63cfdc24544caac85e2574c53bca2
Autor:
Courtney Schiebout, H. Robert Frost
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background A vital step in analyzing single-cell data is ascertaining which cell types are present in a dataset, and at what abundance. In many diseases, the proportions of varying cell types can have important implications for health and pr
Externí odkaz:
https://doaj.org/article/964bfd9b40a847d18511c921acd82b64
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Gonad development includes sex determination and divergent maturation of the testes and ovaries. Recent advances in measuring gene expression in single cells are providing new insights into this complex process. However, the underlying epige
Externí odkaz:
https://doaj.org/article/d05caea8691042928d918408755731b5
Autor:
Qiang Su, Wanzhong Huang, Yuan Huang, Rixin Dai, Chen Chang, Qiu-Yan Li, Hao Liu, Zhenhao Li, Yuxiang Zhao, Qiang Wu, Di-Guang Pan
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-16 (2024)
Abstract Background Diabetic cardiomyopathy (DCM) poses a growing health threat, elevating heart failure risk in diabetic individuals. Understanding DCM is crucial, with fibroblasts and endothelial cells playing pivotal roles in driving myocardial fi
Externí odkaz:
https://doaj.org/article/0cf49cf7d0d94849a87d87fdfe6a2389
Autor:
Gang Wang, Hangdi Wu, Xiuwen Zhai, Li Zhang, Changming Zhang, Chen Cheng, Xiaodong Xu, Erzhi Gao, Xushen Xiong, Jin Zhang, Zhihong Liu
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Wilms tumor‐1(WT1) is a crucial transcription factor that regulates podocyte development. However, the epigenomic mechanism underlying the function of WT1 during podocyte development has yet to be fully elucidated. Here, single‐cell chro
Externí odkaz:
https://doaj.org/article/c27d86fd5254495eafc3a6bb5ecd4b4b
Autor:
Jin Woo Lee, Hwa-Yong Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The endometrium is a dynamic tissue that undergoes cyclic changes in response to ovarian hormones during the menstrual cycle. These changes are crucial for pregnancy establishment and maintenance. Endometrial stem cells play a pivotal role i
Externí odkaz:
https://doaj.org/article/297b79bea11043bab362a958d0917063
Autor:
Xiaofan Sun, Lisha Zhou, Yi Wang, Guoliang Deng, Xinran Cao, Bowen Ke, Xiaoqi Wu, Yanhong Gu, Haibo Cheng, Qiang Xu, Qianming Du, Hongqi Chen, Yang Sun
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 726-744 (2023)
Colorectal tumors often create an immunosuppressive microenvironment that prevents them from responding to immunotherapy. Cannabidiol (CBD) is a non-psychoactive natural active ingredient from the cannabis plant that has various pharmacological effec
Externí odkaz:
https://doaj.org/article/4101cded7c4442f3a463fa70945645d8
Autor:
Kathrin Luise Braband, Annekathrin Silvia Nedwed, Sara Salome Helbich, Malte Simon, Niklas Beumer, Benedikt Brors, Federico Marini, Michael Delacher
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a cutting-edge technology that enables researchers to assess genome-wide chromatin accessibility and to characterize cell type specific gene-regulatory programs. Recent tec
Externí odkaz:
https://doaj.org/article/bdede6e05b164ad49a76afcd360229c0
Publikováno v:
PeerJ, Vol 11, p e16105 (2023)
Background In vitro fertilization-embryo transfer (IVF-ET) is a crucial assisted reproductive technology for treating infertility. However, recurrent implantation failure (RIF), a significant challenge in IVF-ET success, remains unresolved. This stud
Externí odkaz:
https://doaj.org/article/1a5a7b824dc54d3ebc275325aa0a6b44