Zobrazeno 1 - 10
of 183
pro vyhledávání: '"sarcomere organization"'
Autor:
Mamta Amrute‐Nayak, Gloria Pegoli, Tim Holler, Alfredo Jesus Lopez‐Davila, Chiara Lanzuolo, Arnab Nayak
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 159-176 (2021)
Abstract Background Chemotherapy is the first line of treatment for cancer patients. However, the side effects cause severe muscle atrophy or chemotherapy‐induced cachexia. Previously, the NF‐κB/MuRF1‐dependent pathway was shown to induce chem
Externí odkaz:
https://doaj.org/article/547fb1c0818f4b7b9dc02ab09613b2fd
Akademický článek
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Akademický článek
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Autor:
John Miller, Taylor Moncrief, Guy M. Benian, Ivana Gaziova, Courtney J. Matheny, Hiroshi Qadota, Andres F. Oberhauser
Publikováno v:
Protein Sci
Proper muscle development and function depend on myosin being properly folded and integrated into the thick filament structure. For this to occur the myosin chaperone UNC-45, or UNC-45B, must be present and able to chaperone myosin. Here we use a com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3eb522ca3933bdb14d2ca583defd991
https://doi.org/10.1002/pro.4180
https://doi.org/10.1002/pro.4180
Autor:
Joshua M. Gorham, Christine E. Seidman, Christopher S. Chen, Jonathan G. Seidman, Subramanian Sundaram, Christopher N. Toepfer, Radhika Agarwal, Jourdan K. Ewoldt, Steven P. Gygi, Joao A. Paulo, Steven R. DePalma, Qi Zhang, Anant Chopra
Publikováno v:
Circ Res
Rationale: Dominant heterozygous variants in filamin C ( FLNC ) cause diverse cardiomyopathies, although the underlying molecular mechanisms remain poorly understood. Objective: We aimed to define the molecular mechanisms by which FLNC variants alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d52388e1e32f951f89c01d30cc4b3c6
https://doi.org/10.1161/circresaha.120.317076
https://doi.org/10.1161/circresaha.120.317076
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss 1, Pp 1-13 (2021)
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology
Background Proper muscle function is heavily dependent on highly ordered protein complexes. UNC45 is a USC (named since this region is shared by three proteins UNC45/CRO1/She4P) chaperone that is necessary for myosin incorporation into the thick fila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cec945dda8b8b39cbcaf22c57f12c1a
https://doaj.org/article/12d26a3ee7e547e6ba41e765236f1d93
https://doaj.org/article/12d26a3ee7e547e6ba41e765236f1d93
Autor:
Aimilia Varela, Ioanna Kostavasili, Alexia Polissidis, Ismini Kloukina, Manolis Mavroidis, Modestos Nakos-Bimpos, Mary Tsikitis, Elsa Tsoupri, Yassemi Capetanaki, Despoina Miliou, Constantinos H. Davos, Eleni Vasilaki
Publikováno v:
Cell and Tissue Research. 385:675-696
The desmin-associated protein myospryn, encoded by the cardiomyopathy-associated gene 5 (CMYA5), is a TRIM-like protein associated to the BLOC-1 (Biogenesis of Lysosomes Related Organelles Complex 1) protein dysbindin. Human myospryn mutations are li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae358b0b1647d5763683eac637c60820
https://doi.org/10.1007/s00441-021-03447-2
https://doi.org/10.1007/s00441-021-03447-2
Autor:
Jeroen M. Stein, Ulgu Arslan, Marnix Franken, Jessica C. de Greef, Sian E. Harding, Neda Mohammadi, Valeria V. Orlova, Milena Bellin, Christine L. Mummery, Berend J. van Meer
Publikováno v:
Current Protocols, 2(7):e462. Wiley
Sarcomeres are the structural units of the contractile apparatus in cardiac and skeletal muscle cells. Changes in sarcomere characteristics are indicative of changes in the sarcomeric proteins and function during development and disease. Assessment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91393af88df7841738d89ad1195777dd
https://doi.org/10.1002/cpz1.462
https://doi.org/10.1002/cpz1.462
Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model
Autor:
Sarah Derde, Greet Van den Berghe, Barbara Reischl, Dominik Schneidereit, Lawrence Van Helleputte, Ludo Van Den Bosch, Lies Langouche, Oliver Friedrich, Michael Haug, Ruben Weckx, Chloë Goossens
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 2, Pp 443-455 (2021)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle
BACKGROUND: Prolonged critically ill patients frequently develop debilitating muscle weakness that can affect both peripheral nerves and skeletal muscle. In-depth knowledge on the temporal contribution of neural and muscular components to muscle weak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add67dbe654a8faa874cbee65af87ad2
https://doi.org/10.1002/jcsm.12668
https://doi.org/10.1002/jcsm.12668
Autor:
Mamta Amrute-Nayak, Alfredo Jesus López-Dávila, Arnab Nayak, Gloria Pegoli, Chiara Lanzuolo, Tim Holler
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 159-176 (2021)
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 159-176 (2021)
Background Chemotherapy is the first line of treatment for cancer patients. However, the side effects cause severe muscle atrophy or chemotherapy‐induced cachexia. Previously, the NF‐κB/MuRF1‐dependent pathway was shown to induce chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49433e41c23fb6a00b744d794676fedb
http://europepmc.org/articles/PMC7890149
http://europepmc.org/articles/PMC7890149