Zobrazeno 1 - 10
of 18
pro vyhledávání: '"sGC, soluble guanylate cyclase"'
Autor:
Patrik Aronsson, Johanna Stenqvist, Ena Ferizovic, Emelie Danielsson, Anna Jensen, Ulf Simonsen, Michael Winder
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Due to its chemical properties, functional responses to nitric oxide (NO) are often difficult to examine. In the present study, we established a method to produce NO in an aqueous solution and validated its capacity to evoke functional
Externí odkaz:
https://doaj.org/article/e0906a673e284dd1bf114239d20d3ff4
Akademický článek
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Autor:
Matthias R. Meyer, Matthias Barton
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • The role of ERα non-nuclear signaling in female heart failure was investigated, using a novel mouse line in which ERα non-nuclear signaling was selectively disrupted by inhibiting the interaction between ERα and
Highlights • The role of ERα non-nuclear signaling in female heart failure was investigated, using a novel mouse line in which ERα non-nuclear signaling was selectively disrupted by inhibiting the interaction between ERα and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b353abdb69e8f5cf341a6505d8e5ce74
http://europepmc.org/articles/PMC7091503
http://europepmc.org/articles/PMC7091503
Publikováno v:
The Journal of Biological Chemistry
Soluble guanylate cyclase (sGC) is a heme-containing heterodimeric enzyme that generates many molecules of cGMP in response to its ligand nitric oxide (NO); sGC thereby acts as an amplifier in NO-driven biological signaling cascades. Because sGC help
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79efd3871dc9136463a499ab2b9b8061
http://europepmc.org/articles/PMC7949132
http://europepmc.org/articles/PMC7949132
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 22, Iss, Pp 163-168 (2019)
International Journal of Cardiology. Heart & Vasculature
IJC Heart and Vasculature, 22, 163
International Journal of Cardiology. Heart & Vasculature
IJC Heart and Vasculature, 22, 163
Background: To improve clinical outcome, patients with inoperable and residual chronic thromboembolic pulmonary hypertension (CTEPH) can be treated with riociguat. The aim of this study is to explore long-term outcomes and to compare our ‘real worl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5cbcb130269efb178d5ef206e47e83
https://dspace.library.uu.nl/handle/1874/385234
https://dspace.library.uu.nl/handle/1874/385234
Autor:
Ezzat A. Ismail, Ahmed I. El-Sakka
Publikováno v:
Arab Journal of Urology
Objective To review contemporary knowledge concerning the innovative trends and perspectives in the treatment of erectile dysfunction (ED). Methods Medline was reviewed for English-language journal articles between January 2000 and March 2016, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b03c8eb9f666c105d8590dfe7e21900
Autor:
Mota, Filipa, Gane, Paul, Hampden-Smith, Kathryn, Allerston, Charles K., Garthwaite, John, Selwood, David L.
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
Soluble guanylate cyclase (sGC) is a haem containing enzyme that regulates cardiovascular homeostasis and multiple mechanisms in the central and peripheral nervous system. Commonly used inhibitors of sGC activity act through o
Soluble guanylate cyclase (sGC) is a haem containing enzyme that regulates cardiovascular homeostasis and multiple mechanisms in the central and peripheral nervous system. Commonly used inhibitors of sGC activity act through o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fca0e5f89e397949cceb857cadb1ba01
Autor:
Neubauer, Regina, Wölkart, Gerald, Opelt, Marissa, Schwarzenegger, Christine, Hofinger, Marielies, Neubauer, Andrea, Kollau, Alexander, Schmidt, Kurt, Schrammel, Astrid, Mayer, Bernd
Publikováno v:
Biochemical Pharmacology
Graphical abstract
The vascular bioactivation of the antianginal drug nitroglycerin (GTN), yielding 1,2-glycerol dinitrate and nitric oxide or a related activator of soluble guanylate cyclase, is catalyzed by aldehyde dehydrogenase-2 (ALDH2) in
The vascular bioactivation of the antianginal drug nitroglycerin (GTN), yielding 1,2-glycerol dinitrate and nitric oxide or a related activator of soluble guanylate cyclase, is catalyzed by aldehyde dehydrogenase-2 (ALDH2) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::452c4ad981692c47a82025748b6c337a
http://europepmc.org/articles/PMC4321882
http://europepmc.org/articles/PMC4321882
Publikováno v:
Neuroscience
Nitric oxide produced by neuronal nitric oxide synthase (nNOS) in the spinal cord is required for development of hyperalgesia in inflammatory and neuropathic pain states. nNOS is expressed by some dorsal horn neurons, and an early study that used a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2978a561244422c20b170b71585b1bb2
http://europepmc.org/articles/PMC3183229
http://europepmc.org/articles/PMC3183229
Autor:
Martínez Pereyra V; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Seitz A; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Hubert A; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Beck S; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Germany., Schwab M; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart and University of Tübingen, Germany.; Department of Clinical Pharmacology, University of Tübingen, Tübingen, Germany.; Department of Pharmacy and Biochemistry, University of Tübingen, Tübingen, Germany., Bekeredjian R; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Sechtem U; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany., Ong P; Department of Cardiology, Robert-Bosch-Hospital, Stuttgart, Germany.
Publikováno v:
JACC. Case reports [JACC Case Rep] 2021 Feb 24; Vol. 3 (3), pp. 392-396. Date of Electronic Publication: 2021 Feb 24 (Print Publication: 2021).