Zobrazeno 1 - 10
of 59
pro vyhledávání: '"sACE2"'
Autor:
Izumi Nagatomo, Kaori Nakanishi, Ryohei Yamamoto, Seiko Ide, Chisaki Ishibashi, Toshiki Moriyama, Keiko Yamauchi-Takihara
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Increased expression of angiotensin-converting enzyme 2 (ACE2) is one of the likely explanations for disease severity in patients with coronavirus disease 2019 (COVID-19). In this study, we aimed to test whether soluble ACE2 (sACE2) levels are correl
Externí odkaz:
https://doaj.org/article/dd1906ceec1d48edb437efe90269a20b
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 92-97 (2021)
The third outbreak of coronavirus (CoV) infection (after SARS-CoV and MERS-CoV) caused by a novel CoV (SARS-CoV-2) of the genus Beta-coronavirus has become a global pandemic. CoVs are enveloped viruses whose proteins include spike (S), membrane (M),
Externí odkaz:
https://doaj.org/article/99fc9041294348aa97680668a6677e6d
Publikováno v:
BBA Advances, Vol 2, Iss , Pp 100044- (2022)
Once inhaled, SARS-CoV-2 particles enter respiratory ciliated cells by interacting with angiotensin converting enzyme 2 (ACE2). Understanding the nature of ACE2 within airway tissue has become a recent focus particularly in light of the COVID-19 pand
Externí odkaz:
https://doaj.org/article/8bf2b0283158428091a1207721705f8b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Currently, the COVID-19 pandemic is an international challenge, largely due to lack of effective therapies. Pharmacotherapy has not yet been able to find a definitive treatment for COVID-19. Since SARS-CoV-2 affects several organs, treatment strategi
Externí odkaz:
https://doaj.org/article/40a6a147e96b4ec3a0f9adf7e0c50cd3
Autor:
Noha Mousaad Elemam, Hind Hasswan, Hayat Aljaibeji, Narjes Saheb Sharif-Askari, Rabih Halwani, Jalal Taneera, Nabil Sulaiman
Publikováno v:
Life, Vol 12, Iss 4, p 575 (2022)
Background: The main mechanism of viral entry in COVID-19 infection is through the angiotensin-converting enzyme 2 (ACE2) receptor present in the lungs. Numerous studies suggested a clinical significance of risk factors, such as gender, obesity, and
Externí odkaz:
https://doaj.org/article/23d98d1c549c4a34b568fb58948fcc53
Akademický článek
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Publikováno v:
Viruses, Vol 13, Iss 11, p 2243 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters host cells mainly by the angiotensin converting enzyme 2 (ACE2) receptor, which can recognize the spike (S) protein by its extracellular domain. Previously, recombinant soluble A
Externí odkaz:
https://doaj.org/article/092053f60eb24fc79b2cfaf504077729
Autor:
Alice G. Vassiliou, Alexandros Zacharis, Chrysi Keskinidou, Edison Jahaj, Maria Pratikaki, Parisis Gallos, Ioanna Dimopoulou, Anastasia Kotanidou, Stylianos E. Orfanos
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 695 (2021)
A damaged endothelium is an underlying condition of the many complications of COVID-19 patients. The increased mortality risk associated with diseases that have underlying endothelial dysfunction, such as acute respiratory distress syndrome (ARDS), s
Externí odkaz:
https://doaj.org/article/93a8790976514362a336a9608c182d9a
Autor:
Paul, Edit
Viruset SARS-CoV-2 binder till det membranbundna enzymet angiotensinkonvertas 2 (ACE2). ACE2 är även en del av Renin-Angiotensin-Aldosteron-systemet (RAAS) och Kallikrein-Kinin-systemet (KKS). Den enzymatiska delen av ACE2 klyvs från cellmembranet
Externí odkaz:
http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-121822
Autor:
Alisan Kayabolen, Ugur Akcan, Doğancan Özturan, Hivda Ulbegi‐Polat, Gizem Nur Sahin, Nareg Pinarbasi‐Degirmenci, Canan Bayraktar, Gizem Soyler, Ehsan Sarayloo, Elif Nurtop, Berna Ozer, Gulen Guney‐Esken, Tayfun Barlas, Ismail Selim Yildirim, Ozlem Dogan, Sercin Karahuseyinoglu, Nathan A. Lack, Mehmet Kaya, Cem Albayrak, Fusun Can, Ihsan Solaroglu, Tugba Bagci‐Onder
Publikováno v:
Advanced Science
Soluble ACE2 (sACE2) decoys are promising agents to inhibit SARS-CoV-2, as their efficiency is unlikely to be affected by escape mutations. However, their success is limited by their relatively poor potency. To address this challenge, multimeric sACE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b78b2d01572f8bfd0fb1e26e2b1446
http://hdl.handle.net/20.500.12645/30903
http://hdl.handle.net/20.500.12645/30903