Zobrazeno 1 - 10
of 1 151
pro vyhledávání: '"rutaecarpine."'
Autor:
Yong He, Xin Wang, Li-Sheng Chen, Lei Chang, Ting-Ting He, Ao-Zhe Zhang, Hao-Tian Li, Shi-Zhang Wei, Man-Yi Jing, Yan-Ling Zhao
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 10, Iss 3, Pp 303-315 (2024)
Objective: Chronic atrophic gastritis (CAG) is a complex and burdensome disease. However, side effects and compliance issues cannot be ignored due to the long treatment cycle. Numerous studies have confirmed the effectiveness of rutaecarpine (RUT) fo
Externí odkaz:
https://doaj.org/article/511027d26c2a4b128d6419618594b86c
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 345-355 (2024)
Psoriasis is accepted as a chronic, inflammatory, immune-mediated skin disease triggered by complex environmental and genetic factors. For a long time, disease recurrence, drug rejection, and high treatment costs have remained enormous challenges and
Externí odkaz:
https://doaj.org/article/83e37c34a1674095866b3e94dfc3a076
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Evodia rutaecarpa, a traditional herbal drug, is widely used as an analgesic and antiemetic. Many studies have confirmed that Evodia rutaecarpa has an anticancer effect. Here, our study explored the bioactive ingredients in Evodia
Externí odkaz:
https://doaj.org/article/05c4f6e9f6c040d8b7c03d654c304ae1
Publikováno v:
Applied Sciences, Vol 14, Iss 18, p 8124 (2024)
Indole alkaloids, a class of plant-derived nitrogen-containing compounds, have emerged as promising candidates for osteoporosis treatment. Their favorable biocompatibility profile demonstrated efficacy in preclinical models, and low reported toxicity
Externí odkaz:
https://doaj.org/article/f9881cc0edc549edbf2ba1d8d1ce9548
Publikováno v:
Toxics, Vol 12, Iss 7, p 515 (2024)
In this study, we investigated whether rutaecarpine could aggravate acetaminophen-induced acute liver damage in vivo and in vitro. CCK-8 and apoptosis assays were performed to verify the cytotoxicity of acetaminophen to L02 cells with or without ruta
Externí odkaz:
https://doaj.org/article/4aa6d598e27f41b5a86e5091e29e6a2e
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 2403-2404 (2024)
Yu Z, Chan S, Wang X, et al. Drug Des Devel Ther. 2023;17:993–1006. At the authors request, the Editor and Publisher of the journal Drug Design, Development and Therapy have retracted the published article. Following publication of the article, the
Externí odkaz:
https://doaj.org/article/2a149b8edf6844248810a3a7d247cd5e
Autor:
Jie Lei, Yujia Pan, Rui Gao, Bin He, Zifeng Wang, Xinxing Lei, Zijian Zhang, Na Yang, Min Yan
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Triple-negative breast cancer (TNBC) is one of the most aggressive human cancers and has poor prognosis. Approximately 80% of TNBC cases belong to the molecular basal-like subtype, which can be exploited therapeutically by inducin
Externí odkaz:
https://doaj.org/article/27f85126c65746f5859e00bfdc93205b
Autor:
Sivappa Rasapalli, Yanchang Huang, Vamshikrishna Reddy Sammeta, Reem Alshehry, Fazmina Anver, James A. Golen, Shivasankar Krishnamoorthy, Subhash P. Chavan
Publikováno v:
Tetrahedron Chem, Vol 9, Iss , Pp 100062- (2024)
A short diversity oriented total synthesis (DOTS) of substituted rutaecarpines, homo-luotonins, homo-vasicinone, homo-isaindigotones and homo-vasnetine has been achieved from the key tricyclic intermediate. The [6,6,6] tricyclic ketone, the mackinazo
Externí odkaz:
https://doaj.org/article/c42248d07d464fc4aa83cbbc53e5e28a
Autor:
Li-Qing Qin, Zi-Yu Gu, Nan-Ying Chen, Pei-Dong Liu, Liu-Song Lan, Xin-Wei Li, Jun-Cheng Su, Gui-Fa Su, Dong-Liang Mo, Cheng-Xue Pan
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101330- (2024)
Natural products are a rich resource in drug discovery. In the report, series novel rutaecarpine-derived compounds with potent anti-inflammatory activity and therapeutic efficacy against dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) we
Externí odkaz:
https://doaj.org/article/97ee198048e441a7b158cff9ede24673
Autor:
Shengying Lin, Xiaoyang Wang, Roy Wai-Lun Tang, Ran Duan, Ka Wing Leung, Tina Ting-Xia Dong, Sarah E. Webb, Andrew L. Miller, Karl Wah-Keung Tsim
Publikováno v:
Molecules, Vol 29, Iss 11, p 2636 (2024)
COVID-19 continues to spread around the world. This is mainly because new variants of the SARS-CoV-2 virus emerge due to genomic mutations, evade the immune system and result in the effectiveness of current therapeutics being reduced. We previously e
Externí odkaz:
https://doaj.org/article/8cbda782edb04c3c8cbb89626aaf8f58