Zobrazeno 1 - 10
of 213
pro vyhledávání: '"rs12979860"'
Publikováno v:
BAG. Journal of Basic and Applied Genetics, Vol 33, Iss 2, Pp 19-25 (2022)
Human interferon-λ4 is a cytokine involved in early stages of antiviral responses. Strikingly, some allelic variants with diminished antiviral activity reduce the susceptibility to viral infections, thus they would have suffered a positive selection
Externí odkaz:
https://doaj.org/article/6c51b9e8d0794d5f84b3179d15f05f43
Autor:
Yaneli Juárez-Vicuña, Julia Pérez-Ramos, Laura Adalid-Peralta, Fausto Sánchez, Laura Aline Martínez-Martínez, María del Carmen Ortiz-Segura, Edgar Pichardo-Ontiveros, Adrián Hernández-Díazcouder, Luis M. Amezcua-Guerra, Julian Ramírez-Bello, Fausto Sánchez-Muñoz
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a complex etiology. Various genetic factors are associated with susceptibility to developing SLE and contribute to its onset and progression. Different single-nucleotide polymorphisms (
Externí odkaz:
https://doaj.org/article/9c1935b1e3194e6da74a4c661fe0a1fd
Publikováno v:
Clinical and Experimental Gastroenterology, Vol Volume 12, Pp 433-439 (2019)
Wei Hou,1,2 Kunyan Qiao,1 Zhixiao Huo,1 Yanan Du,3 Cindy Wang,2 Wing-Kin Syn2,4 1Tianjin Second People’s Hospital and Tianjin Institute of Hepatology, Tianjin, People’s Republic of China; 2Division of Gastroenterology and Hepatology, Department o
Externí odkaz:
https://doaj.org/article/96bd8bfa82bf4e228ca4bd250ad561d4
Akademický článek
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Autor:
Natalia Echeverría, Daniela Chiodi, Pablo López, Adriana Sanchez Ciceron, Jenniffer Angulo, Marcelo López-Lastra, Paola Silvera, Adrian Canavesi, Carla Bianchi, Valentina Colistro, Juan Cristina, Nelia Hernandez, Pilar Moreno
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background Host single-nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) locus are associated with sustained virological response to antiviral therapy and with spontaneous Hepatitis C Virus (HCV) clearance. Prevalence of these
Externí odkaz:
https://doaj.org/article/22126b4aa38c40fbb211a901bd98e525
Autor:
Belson Rugwizangoga, Maria E. Andersson, Jean-Claude Kabayiza, Malin S. Nilsson, Brynja Ármannsdóttir, Johan Aurelius, Staffan Nilsson, Kristoffer Hellstrand, Magnus Lindh, Anna Martner
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Polymorphisms in the interferon lambda gene locus (IFNL) such as the IFNL4 genetic variants rs12979860 and rs368234815 are predictive of resolution of hepatitis C virus infection, but information about the impact of these variants in other infections
Externí odkaz:
https://doaj.org/article/772c96687b554e0abbe535749e2fd851
Akademický článek
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Autor:
Mauro Vigano, Pietro Lampertico
Publikováno v:
European Medical Journal Hepatology, Vol 1, Iss 1, Pp 52-56 (2013)
Pegylated interferon (Peg-IFN) may achieve a sustained off-treatment response in 20-30% of the patients with chronic hepatitis B (CHB). However, given the high cost of treatment, the frequent side effects, and the lack of effectiveness in a large pro
Externí odkaz:
https://doaj.org/article/39fc4a8b595d4129b48823a8830148f7
Publikováno v:
Journal of leukocyte biology
Human IFN-λ4 is expressed by only a subset of individuals who possess the ΔG variant allele at the dinucleotide polymorphism rs368234815. Recent genetic studies have shown an association between rs368234815 and different infectious and inflammatory
Autor:
Juliene Antonio Ramos, Ana Lúcia de Araújo Ramos, Luisa Hoffmann, Renata de Mello Perez, Henrique Sérgio Moraes Coelho, Turán Péter Ürményi, Rosane Silva, Edson Rondinelli, Cristiane Alves Villela-Nogueira
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 107, Iss 7, Pp 888-892 (2012)
Single nucleotide polymorphisms (SNPs) in the interleukin (IL)28B locus have been associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV)-treated chronic hepatitis C virus (HCV)-infected patients in European and Afric
Externí odkaz:
https://doaj.org/article/b60e9b7fd5e04a3f85391e1285789777