Zobrazeno 1 - 10
of 1 044
pro vyhledávání: '"rock inhibitor"'
Autor:
Jiwan Choi, Seoon Kang, Hye-In An, Chae-Eun Kim, Sanghwa Lee, Chan-Gi Pack, Young-In Yoon, Hana Jin, Yong-Pil Cho, Chong Jai Kim, Jung-Man Namgoong, Jun Ki Kim, Eunyoung Tak
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Human mesenchymal stem cells originating from umbilical cord matrix are a promising therapeutic resource, and their differentiated cells are spotlighted as a tissue regeneration treatment. However, there are limitations to the med
Externí odkaz:
https://doaj.org/article/b6748173238948e0a688fa5db16d04e2
Autor:
Wenyuanfeng Chen, Yuan Qu, Yining Liu, Guorui Zhang, Hasan M. Sharhan, Xinzhu Zhang, Kunwu Zhang, Baocheng Cao
Publikováno v:
Progress in Orthodontics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Orthodontic pain affects the physical and mental health of patients. The spinal trigeminal subnucleus caudalis (SPVC) contributes to the transmission of pain information and serves as a relay station for integrating orofacial dama
Externí odkaz:
https://doaj.org/article/bde248378bd648eb9de2d916a6967999
Autor:
Sawita Santiviparat, Theerawat Swangchan-Uthai, Tom A. E. Stout, Supranee Buranapraditkun, Piyathip Setthawong, Teeanutree Taephatthanasagon, Watchareewan Rodprasert, Chenphop Sawangmake, Theerawat Tharasanit
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract To better understand molecular aspects of equine endometrial function, there is a need for advanced in vitro culture systems that more closely imitate the intricate 3-dimensional (3D) in vivo endometrial structure than current techniques. Ho
Externí odkaz:
https://doaj.org/article/ff2ccc1a43ed4b44a33282f53ac0284f
Autor:
Wei Fan, Bo Wei, Xuyan Chen, Yi Zhang, Pingping Xiao, Kaiyan Li, Yi qin Zhang, Jinmei Huang, Lin Leng, Richard Bucala
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-11 (2024)
Abstract Objective Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by abnormal activation of the type I interferon (IFN) pathway, which results in tissue inflammation and organ damage. We explored the role of the RhoA GTPas
Externí odkaz:
https://doaj.org/article/99f0d7bfdab2483e9b9996dfe8d98fee
Autor:
Kirk Patrick Carreon Catral, Choi-Yee Tse, Wei-Ying Yang, Choi-Ying Ling, Oi-Lam Kwok, Kit-Ying Choy, Da-Qian Lu, Jing-Fang Bian, Thomas Chuen Lam, Dennis Yan-Yin Tse, Samantha Sze-Wan Shan
Publikováno v:
Cells, Vol 13, Iss 22, p 1907 (2024)
Age-related macular degeneration (AMD) is a degenerative eye disease leading to central vision loss and is characterized by dysregulated autophagy of the retinal pigment epithelium (RPE) layer. Recent studies have suggested that rho-associated protei
Externí odkaz:
https://doaj.org/article/b8ef45dad96d4e2a9df365739447690e
Akademický článek
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Autor:
Mohit Parekh, Annie Miall, Ashley Chou, Lara Buhl, Neha Deshpande, Marianne O. Price, Francis W. Price, Ula V. Jurkunas
Publikováno v:
Cells, Vol 13, Iss 14, p 1218 (2024)
Descemet’s Stripping Only (DSO) is a surgical technique that utilizes the peripheral corneal endothelial cell (CEnC) migration for wound closure. Ripasudil, a Rho-associated protein kinase (ROCK) inhibitor, has shown potential in DSO treatment; how
Externí odkaz:
https://doaj.org/article/8968e4afb16747cfb223dadd35827377
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 7, Pp 2756-2759 (2023)
Purpose: Ripasudil is a class of drug which alters the trabecular meshwork to increase the aqueous outflow and has been shown to be effective in pseudoexfoliative glaucoma (PXF G). This study aimed at assessing the efficacy and safety profile of ripa
Externí odkaz:
https://doaj.org/article/7c78ef60e13d49cf891a8834bffbab41
Publikováno v:
Oman Journal of Ophthalmology, Vol 16, Iss 1, Pp 94-97 (2023)
Rho-associated protein kinase inhibitor (ROCK) therapy for corneal endothelial dysfunction or damage other than glaucoma has been reported with few ocular side effects. We report reticular epithelial edema (REE) with netarsudil (0.02%) therapy in fou
Externí odkaz:
https://doaj.org/article/e95f41896a4244638356e73b90c904ac
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
In this study, it was hypothesized that the addition of an appropriate concentration of Y-27632 (a ROCK inhibitor) to the freezing extender prevents cryopreservation-induced apoptosis and improves embryonic development after in vitro fertilization (I
Externí odkaz:
https://doaj.org/article/3626856a6eb448c6b795a3bb930b9cce