Zobrazeno 1 - 10
of 1 237
pro vyhledávání: '"rna-seq analysis"'
Autor:
Duong H. T. Vo, Thomas Thorne
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Gene interaction networks are graphs in which nodes represent genes and edges represent functional interactions between them. These interactions can be at multiple levels, for instance, gene regulation, protein-protein interaction
Externí odkaz:
https://doaj.org/article/c9ed544d0571402fa6c62c07f190bb5c
Autor:
Hongkai Yao, Weifang Tong, Yunping Song, Ruoyu Li, Xuerui Xiang, Wen Cheng, Yunjiao Zhou, Yijing He, Yi Yang, Yunxi Liu, Siguang Li, Lingjing Jin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract The primary pathological change in Parkinson’s disease (PD) is the progressive degeneration of dopaminergic neurons in the substantia nigra. Additionally, excessive microglial activation and synaptic loss are also typical features observed
Externí odkaz:
https://doaj.org/article/3d44f0e51fd843db87f90dda4d717ec5
Autor:
Vincent Guerlais, Nina Allouch, E. Ashley Moseman, Alicja W. Wojciechowska, Jakub W. Wojciechowski, Isabel Marcelino
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The free-living amoeba Naegleria fowleri (NF) causes a rare but lethal parasitic meningoencephalitis (PAM) in humans. Currently, this disease lacks effective treatments and the specific molecular mechanisms that govern NF pathogenesis and host brain
Externí odkaz:
https://doaj.org/article/f37d226e6a254d8aaba65b5dd28ebc4f
Autor:
Flávia Sardela de Miranda, Dalia Martinez-Marin, Rachel L. Babcock, Maribel Castro, Geetha P. Boligala, Sonia Y. Khan, Kathryn L. Furr, Isabel Castro-Piedras, Nicholas Wagner, Dakota E. Robison, Karla Daniele, Sharda P. Singh, Kevin Pruitt, Michael W. Melkus, Rakhshanda Layeequr Rahman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite recent advances, triple-negative breast cancer (TNBC) patients remain at high risk for recurrence and metastasis, which creates the need for innovative therapeutic approaches to improve patient outcomes. Cryoablation is a promisin
Externí odkaz:
https://doaj.org/article/96a7604dd36f4009ad8d924e431a7be9
Autor:
Xingwang Zhou, Yuanguo Ling, Junshuan Cui, Xiang Wang, Niya Long, Wei Teng, Jian Liu, Xin Xiang, Hua Yang, Liangzhao Chu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Mitochondrial RNA modification (MRM) plays a crucial role in regulating the expression of key mitochondrial genes and promoting tumor metastasis. Despite its significance, comprehensive studies on MRM in lower grade gliomas (LGGs) remain unk
Externí odkaz:
https://doaj.org/article/82ad99fcdfc14648aa47ec7c46e00103
Publikováno v:
Guangdong nongye kexue, Vol 51, Iss 5, Pp 44-55 (2024)
【Objective】Auxin response factors (ARF) are key transcription factors engaged in the auxin signaling system and play significant roles in plant flower and fruit development, organ morphogenesis, hormone control, and stress responses. The study ai
Externí odkaz:
https://doaj.org/article/76ebf563302b43938c7299022d446e5a
Publikováno v:
PeerJ, Vol 12, p e18158 (2024)
Background Cervical cancer (CC) is a neoplasia with a high heterogeneity. We aimed to explore the characteristics of tumor microenvironment (TME) for CC treatment. Methods HPV positive (+) and negative (−) samples from cervical cancer (CC) patients
Externí odkaz:
https://doaj.org/article/b5e29540b2ee49c29e18c91cee112818
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
IntroductionLiquiritigenin (LQ), a natural flavonoid found in traditional Chinese medicine and often administered orally, holds potential to affect both the gut and its microbiota, that potentially mediating or influencing its biological and pharmaco
Externí odkaz:
https://doaj.org/article/81ca17dde9bb4c8493d9936d65512831
Autor:
Nan Li, Jiahao Miao, Yichao Li, Faru Ji, Min Yang, Kunyan Dai, Zixian Zhou, Die Hu, Haiyang Guo, Hong Fang, Hongyang Wang, Maohui Wang, Jing Yang
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37933- (2024)
Rice (Oryza sativa L.) is one of the most extensively farmed food crops, but its development and productivity are significantly impacted by cold stress during the budding period. In this study, transcriptome sequencing was conducted on two types of r
Externí odkaz:
https://doaj.org/article/5c49eb85b2ab4f53aea54d18c4aeec60
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundSenescence-accelerated mouse prone 8 (SAMP8) and age-matched SAMR1 mice are used to study the pathogenesis and therapeutics of Alzheimer’s disease (AD); however, the molecular mechanisms are not completely understood.ObjectiveThis study a
Externí odkaz:
https://doaj.org/article/0f28bf38c3e24ef6a9311d06c955bc64