Zobrazeno 1 - 10
of 3 458
pro vyhledávání: '"ring-closure"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1906-1913 (2024)
A novel facile approach to N-arylpyridoindazolium salts is proposed, based on direct oxidation of the ortho-pyridine substituted diarylamines, either using bis(trifluoroacetoxy)iodobenzene as an oxidant, or electrochemically, via potentiostatic oxida
Externí odkaz:
https://doaj.org/article/8511b35c3c884981b167e1a44f8be639
Publikováno v:
Molbank, Vol 2024, Iss 2, p M1806 (2024)
In the context of our ongoing studies on chromane derivatives as inhibitors of the salicylate synthase from M. tuberculosis, we isolated a new, unexpected compound from the cyclization of 3-(propargyloxy)-5-benzyloxy-benzoic acid methyl ester. Its mo
Externí odkaz:
https://doaj.org/article/165072210f2f470db8aa40ba46e76957
Autor:
Mohammed Farrag El-Behairy, Walaa Hamada Abd-Allah, Mohamed M. Khalifa, Mohamed S. Nafie, Mohamed A. Saleh, Mohammed S. Abdel-Maksoud, Tarfah Al-Warhi, Wagdy M. Eldehna, Ahmed A. Al‐Karmalawy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this research, two novel series of dibenzo[b,f]azepines (14 candidates) were designed and synthesised based on the rigidification principle and following the reported doxorubicin’s pharmacophoric features. The anti-proliferative activity was eva
Externí odkaz:
https://doaj.org/article/c4fb055b92c24a3eb4000d2f73075561
Publikováno v:
Molbank, Vol 2023, Iss 3, p M1694 (2023)
The [1,2,4]triazolo[4,3-a]pyridine derivative 3-(4-(benzyloxy)-3-methoxyphenyl)-[1,2,4]triazolo[4,3-a]pyridine was prepared in a 73% isolated yield by means of an oxidative ring closure of a hydrazine intermediate. Sodium hypochlorite was used as the
Externí odkaz:
https://doaj.org/article/25939739ad4f4ab38818d0accc7125d1
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1649 (2023)
1,2,5-Chalcogenadiazoles fused with electron-withdrawing heterocycles have been actively investigated for the preparation of organic photovoltaic materials. [1,2,5]Oxadiazolo[3,4-d]pyridazines are much less studied than other chalcogenadiazolopyridaz
Externí odkaz:
https://doaj.org/article/8a4359619dd6491f896c2f180975d184
Akademický článek
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Autor:
Dylan R. Nanney, Richard A. Bunce
Publikováno v:
Molbank, Vol 2022, Iss 4, p M1526 (2022)
A synthesis of the title compound and related structures is reported. The procedure involves double alkylation of a β-ketoester followed by double SNAr ring closure from the γ carbon to give a dibenzo[3.3.1]bicyclic unit. This paper appears to be t
Externí odkaz:
https://doaj.org/article/242995059ff94f6b8400196f9c46d29c
Akademický článek
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Autor:
Kaho Nakatani, Hideki Kobara, Noriko Nishiyama, Shintaro Fujihara, Naoya Tada, Kazuhiro Koduka, Takanori Matsui, Taiga Chiyo, Nobuya Kobayashi, Tatsuo Yachida, Joji Tani, Asahiro Morishita, Hajime Isomoto, Tsutomu Masaki
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 13, p 4238 (2023)
Duodenal endoscopic submucosal dissection (ESD) is associated with high incidences of intraoperative complications and delayed adverse events (AEs). Delayed AEs can be reduced by closing the post-ESD defects. We developed a new method of closure afte
Externí odkaz:
https://doaj.org/article/8137afa58f3045c29f9a570bae90df42
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8252 (2023)
The intramolecular Heck reaction is a well-established strategy for natural product total synthesis. When constructing large rings, this reaction is also referred to as Heck macrocyclization, which has proved a viable avenue to access diverse natural
Externí odkaz:
https://doaj.org/article/28f2abe16a4e4974bbd6a311040db855