Zobrazeno 1 - 10
of 9 240
pro vyhledávání: '"rho-kinase"'
Autor:
Élodie Reboussin, Paul Bastelica, Ilyes Benmessabih, Arnaud Cordovilla, Cécile Delarasse, Annabelle Réaux-Le Goazigo, Françoise Brignole-Baudouin, Céline Olmière, Christophe Baudouin, Juliette Buffault, Stéphane Mélik Parsadaniantz
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-21 (2024)
Abstract Background Glaucoma is a leading cause of blindness, affecting retinal ganglion cells (RGCs) and their axons. By 2040, it is likely to affect 110 million people. Neuroinflammation, specifically through the release of proinflammatory cytokine
Externí odkaz:
https://doaj.org/article/78539926c1e24f9ea37b32a906073d74
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 74-86 (2024)
Backgrounds: The functional recovery after peripheral nerve injury remains unsatisfactory. This study aims to perform a comprehensive evaluation of the efficacy of Fasudil Hydrochloride at treating the sciatic nerve transection injury in rats and the
Externí odkaz:
https://doaj.org/article/9e111ead88af4d4fa271c18723b97e65
Publikováno v:
PeerJ, Vol 12, p e18335 (2024)
Aminoglycoside nephrotoxicity stands as a primary contributor to the development of acute intrinsic renal failure. Distinctive characteristic associated with this nephrotoxicity is the occurrence of tubular necrosis, which is why it is commonly refer
Externí odkaz:
https://doaj.org/article/f2a592d5e6f5489abdefa73bbfda5a6f
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 3, Pp 339-345 (2024)
Objective To investigate the effect of dexmedetom idine (DEX) on lung tissue and Ras homolog gene family member A (RhoA)/Rho kinase 1 (ROCK1) signaling pathway in lung tissue of rats with ventilator-induced lung injury (VILI). Methods A VILI rat mode
Externí odkaz:
https://doaj.org/article/4d132828810e4e29a37516fd0c84c481
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 18, Iss 09, Pp 01-02 (2024)
Primary Open Angle Glaucoma (POAG) is one of the leading causes of irreversible blindness worldwide. Netarsudil, a Rho-kinase inhibitor and norepinephrine transporter, has recently been approved for reducing intraocular pressure (IOP), which is the s
Externí odkaz:
https://doaj.org/article/12e2f30efd434d8a831dc157d0670161
Publikováno v:
Taiwan Journal of Ophthalmology, Vol 14, Iss 1, Pp 88-94 (2024)
PURPOSE: This study aimed to evaluate the efficacy of ripasudil in managing various corneal edema conditions. MATERIALS AND METHODS: This single-center retrospective analysis was conducted at Hadassah Medical Center and involved 16 patients with 17 e
Externí odkaz:
https://doaj.org/article/9924ae7f6c5e4585ae1922449cc97d9d
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background The Ca2+-independent contraction of vascular smooth muscle is a leading cause of cardiovascular and cerebrovascular spasms. In the previous study, we demonstrated the involvement of Src family protein tyrosine kinase Fyn and Rho-k
Externí odkaz:
https://doaj.org/article/72a30b4acac94c80919427d2885f0a2e
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 97-108 (2024)
Stefan Futterknecht,1,2 Eleftherios Chatzimichail,1 Konstantin Gugleta,1,3 Georgios D Panos,4,5,* Zisis Gatzioufas1,3,* 1Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland; 2Institute of Molecular and Clinical Ophth
Externí odkaz:
https://doaj.org/article/24c1267ba79f483cad5f68e764b1ba1d