Zobrazeno 1 - 10
of 3 372
pro vyhledávání: '"rhein"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4497-4510 (2024)
Anni Zhao,1,* Xiaomei Liu,1,* Xiping Chen,1,* Sha Na,1,* Hui Wang,1 Xuan Peng,1 Peizhong Kong,1 Lu Li1,2 1Department of Biochemistry and Molecular Biology, School of Integrated Chinese and Western Medicine, Anhui University of Chinese
Externí odkaz:
https://doaj.org/article/e4fe099d9f1348c78b426412194afce3
Autor:
Helison R. P. Carmo, Alejandro Rossel Castillo, Isabella Bonilha, Erica I. L. Gomes, Joaquim Barreto, Filipe A. Moura, Gustavo Gastão Davanzo, Lauar de Brito Monteiro, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Joseane Morari, Flávia Elisa Galdino, Natália S. Brunetti, Guilherme Reis-de-Oliveira, Victor Corasolla Carregari, Wilson Nadruz, Daniel Martins-de-Souza, Alessandro S. Farias, Licio A. Velloso, José Luiz Proenca-Modena, Marcelo A. Mori, Watson Loh, Deepak L. Bhatt, Derek M. Yellon, Sean M. Davidson, Pedro G. De Oliveira, Pedro M. Moraes-Vieira, Andrei C. Sposito
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is linked to high mortality, primarily through an intense inflammatory response. Diacerein has emerged as a potential therapy for COVID-19 due to its potential impact in decreasin
Externí odkaz:
https://doaj.org/article/5554f9f3b95f4c22b375bea723beca9b
Publikováno v:
Chemistry, Vol 6, Iss 3, Pp 345-360 (2024)
The conjugate of rhein and artesunate have shown promising effects in inducing immunogenic cell death (ICD) and inhibiting tumor growth. Rhein, a natural anthraquinone derivative found in various medicinal plants such as Rheum palmatum, possesses div
Externí odkaz:
https://doaj.org/article/844c7156e285458694777fdeea99abf6
Autor:
Negar Etebar, Seyed Hootan Hamidi, Saghi Naderpour, Omar Abouali, Seyedeh Harir Hamidi, Behnam Hajipour-Verdom, Alireza Zali, Mozhgan Alipour, Milad Rahimzadegan
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Ras-related C3 botulinum toxin substrate 1 (Rac1) is a small GTPase belonging to the Rho family. It acts as a binary molecular switch regulating several cellular functions, including cell adhesion and migration. Malfunctions due to the P29S mutation
Externí odkaz:
https://doaj.org/article/a9cd091956a84a65a1ef1f4eb52d840d
Autor:
Zhong-Wei Yao, Xiang-Ling Qin, Qi-Long Li, Ling-Hui Pan, Wei-Feng Hu, Su-Ping Ling, Hui Liu, He Zhu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 279, Iss , Pp 116474- (2024)
Rhubarb is widely used in health care, but causing a great amount of rhein-containing herbal residue. Rhein with several toxicities might pollute environment, damage ecology and even hazard human health if left untreated. In this study, the degradati
Externí odkaz:
https://doaj.org/article/3cc09250e9654b5ea618a62f8ba8810d
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundParkinson’s disease (PD) is a common neurodegenerative disease with a rapid increase in incidence in recent years. Existing treatments cannot slow or stop the progression of PD. It was proposed that neuroinflammation leads to neuronal dea
Externí odkaz:
https://doaj.org/article/ae286903f32f4c81b6041fbee246f0e9
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background Rhein can significantly delay the progression of chronic nephropathy. However, its mechanism of action has not been adequately elaborated, which hinders its extensive clinical application. In this work, the effects of rhein on mod
Externí odkaz:
https://doaj.org/article/8bfd82af8e104e73a9b29bbbb7f43d71
Autor:
Lu Han, Tao Zang, Lulu Tan, Dunsheng Liang, Tengfei Long, Xuwei Liu, Xiaofan Shen, Hao Ren, ZhiPeng Li, Zhaoxiang Lu, Shengqiu Tang, Xiaoping Liao, Yahong Liu, Chaoqun Zhang, Jian Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Salmonellosis is a globally extensive food-borne disease, which threatens public health and results in huge economic losses in the world annually. The rising prevalence of antibiotic resistance in Salmonella poses a significant global concer
Externí odkaz:
https://doaj.org/article/5b15d0a6663e4088b741ccf11384d722