Zobrazeno 1 - 10
of 159
pro vyhledávání: '"rgs5"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Major depressive disorder (MDD), characterized by severe neuropsychiatric symptoms and significant cognitive deficits, continues to present both etiological and therapeutic challenges. However, the specific underlying mechanisms and the
Externí odkaz:
https://doaj.org/article/d4f222ff786e4a4ab223261286dd69f4
Akademický článek
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Publikováno v:
Vascular Health and Risk Management, Vol Volume 19, Pp 673-688 (2023)
Guofang Lu,1,2,* Rui Du,3,* Yali Liu,1 Shumiao Zhang,1 Juan Li,1 Jianming Pei1 1Department of Physiology and Pathophysiology, National Key Discipline of Cell Biology, Fourth Military Medical University, Xi’an, 710032, People’s Republic of
Externí odkaz:
https://doaj.org/article/ecb4b98004504abdbb791d1bafd7bf9e
Autor:
Shu Yin, Xin-yue Ma, Ying-feng Sun, Yan-qing Yin, Ying Long, Chun-lai Zhao, Jun-wei Ma, Sen Li, Yan Hu, Ming-tao Li, Gang Hu, Jia-wei Zhou
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Astrocytes contribute to chronic neuroinflammation in a variety of neurodegenerative diseases, including Parkinson's disease (PD), the most common movement disorder. However, the precise role of astrocytes in neuroinflammation remains incomp
Externí odkaz:
https://doaj.org/article/54b411ae89054fc88270909e3dad6f2a
Autor:
Trevor S. Anderson, Amanda L. McCormick, Elizabeth A. Daugherity, Mariam Oladejo, Izuchukwu F. Okpalanwaka, Savanna L. Smith, Duke Appiah, Laurence M. Wood, Devin B. Lowe
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTColorectal cancer (CRC) remains a leading cause of cancer-related mortality despite efforts to improve standard interventions. As CRC patients can benefit from immunotherapeutic strategies that incite effector T cell action, cancer vaccines r
Externí odkaz:
https://doaj.org/article/dbc4fb81d0534fbca894030511279aae
Akademický článek
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Publikováno v:
Biology Open, Vol 11, Iss 10 (2022)
Adaptive biological mechanisms to hypoxia are crucial to maintain oxygen homeostasis, especially in the brain. Pericytes, cells uniquely positioned at the blood-brain interface, respond fast to hypoxia by expressing regulator of G-protein signalling
Externí odkaz:
https://doaj.org/article/cb8e8f8dc24f48afb3236373a20f561a
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5843 (2023)
Resmetirom, a liver-directed, orally active agonist of THR-β, could play a favorable role in treating NASH, but little is known about the underlying mechanism. A NASH cell model was established to test the preventive effect of resmetirom on this dis
Externí odkaz:
https://doaj.org/article/9677492d0a934530a373e30737d63347
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1220 (2022)
Ritodrine, a β2-adrenergic receptor agonist, is among most commonly prescribed tocolytic agents. This study aimed to evaluate the associations of single nucleotide polymorphisms in GNAS, RGS2, and RGS5 with the risk of ritodrine-induced adverse even
Externí odkaz:
https://doaj.org/article/9db627541fef48adb39fa40108e18052
Publikováno v:
Stem Cells. 41:493-504
Regulator of G protein signaling 5 (RGS5) is a GTPase activator for heterotrimeric G-protein α-subunits, shown to be a marker of pericytes. Bone marrow stromal cell population (BMSCs) is heterogeneous. Populations of mesenchymal progenitors, cells s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85af67cf13bea6a90a3d99bfe24030b4
https://doi.org/10.1093/stmcls/sxad020
https://doi.org/10.1093/stmcls/sxad020