Zobrazeno 1 - 10
of 361
pro vyhledávání: '"retinal ischemia/reperfusion"'
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-14 (2024)
Abstract Background Retinal ischemia/reperfusion (IR) injury is a common pathological process in many ophthalmic diseases. Interleukin-1β (IL-1β) is an important inflammatory factor involved in the pathology of retinal IR injury, but the mechanism
Externí odkaz:
https://doaj.org/article/4aa7bfef09ca44159422ce0a3df21f30
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 9, Pp 1599-1605 (2024)
AIM: To investigate the antioxidant protective effect of Lycium barbarum glycopeptide (LbGP) pretreatment on retinal ischemia-reperfusion (I/R) injury (RIRI) in rats. METHODS: RIRI was induced in Sprague Dawley rats through anterior chamber perfusion
Externí odkaz:
https://doaj.org/article/c7e7b90b142c4b658007abf80b5f5279
Autor:
Rami A. Shahror, Esraa Shosha, Carol Morris, Melissa Wild, Shengyu Mu, Gabor Csanyi, Marjan Boerma, Nancy J. Rusch, Abdelrahman Y. Fouda
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Ischemia-induced retinopathy is a hallmark finding of common visual disorders including diabetic retinopathy (DR) and central retinal artery and vein occlusions. Treatments for ischemic retinopathies fail to improve clinical outcomes and the
Externí odkaz:
https://doaj.org/article/2e407af8ac314c83a3be54573247bc0d
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 7, Pp 1027-1031 (2024)
AIM: To investigate the protective effect and mechanism of Danlou tablet on retinal ischemia-reperfusion injury(RIRI)in mice.METHODS: A total of 40 ApoE-/- mice were fed with high fat diet for 6 wk, and the RIRI model was established by anterior cham
Externí odkaz:
https://doaj.org/article/662693a730f9421e918ce9928c282e88
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 6, Pp 902-905 (2024)
The nucleotide-binding oligomerization domain-like receptor protein 3(NLRP3)inflammasome is an inflammatory protein complex, and can participate into the inflammatory response. Upon activation, these inflammasomes can lead to Caspase-1 activation, th
Externí odkaz:
https://doaj.org/article/191795221cf742b1876002443dcb3d7d
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract The tissue damage caused by transient ischemic injury is an essential component of the pathogenesis of retinal ischemia, which mainly hinges on the degree and duration of interruption of the blood supply and the subsequent damage caused by t
Externí odkaz:
https://doaj.org/article/695c67db23ba42bba0cd13481f370c7f
Autor:
Yu-Ze Zhao, Xue-Ning Zhang, Yi Yin, Pei-Lun Xiao, Meng Gao, Lu-Ming Zhang, Shuan-Hu Zhou, Shu-Na Yu, Xiao-Li Wang, Yan-Song Zhao
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 2, Pp 228-238 (2024)
AIM: To observe the effects of N-acetylserotonin (NAS) administration on retinal ischemia-reperfusion (RIR) injury in rats and explore the underlying mechanisms involving the high mobility group box 1 (HMGB1)/receptor for advanced glycation end-produ
Externí odkaz:
https://doaj.org/article/fc39ad5c34ba47bbbf8548d1a79714b2
Autor:
Beáta Pelles-Taskó, Réka Szekeres, Barbara Takács, Anna Szilágyi, Dóra Ujvárosy, Mariann Bombicz, Dániel Priksz, Balázs Varga, Rudolf Gesztelyi, Zoltán Szabó, Zoltán Szilvássy, Béla Juhász
Publikováno v:
Life, Vol 14, Iss 9, p 1148 (2024)
Retinal ischemia–reperfusion (I/R) injury is a critical pathogenic mechanism in various eye diseases, and an effective therapeutic strategy remains unresolved. Natural derivatives have recently reemerged; therefore, in our present study, we examine
Externí odkaz:
https://doaj.org/article/52d5878ff44c4206a3fc88b311d45bd2
Publikováno v:
Indian Journal of Ophthalmology, Vol 72, Iss Suppl 3, Pp S441-S447 (2024)
Purpose: To explore the effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on retinal ischemia–reperfusion injury (RIRI) and the protective effect of N‐hydroxy‐N’‐(4‐n‐butyl‐2‐methylphenyl)formamidine (HET0016) on RIRI. Methods: Ma
Externí odkaz:
https://doaj.org/article/b3884a61d6c0420caba5dc4cbba711bd
Autor:
Jing Liao, Zhaoguang Lai, Guangyi Huang, Jiali Lin, Wei Huang, Yuanjun Qin, Qi Chen, Yaguang Hu, Qiaochu Cheng, Li Jiang, Ling Cui, Haibin Zhong, Min Li, Yantao Wei, Fan Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116042- (2024)
Glaucoma, a prevalent cause of permanent visual impairment worldwide, is characterized by the progressive degeneration of retinal ganglion cells (RGCs). NADPH oxidase (NOX) 1 and NOX4 are pivotal nodes in various retinal diseases. Setanaxib, a potent
Externí odkaz:
https://doaj.org/article/e308d216934142e68bd3920788397abf