Specific in situ immuno-imaging of pulmonary-resident memory lymphocytes in human lungs

Autor: Duncan C. Humphries, Richard A. O’Connor, Hazel L. Stewart, Tom M. Quinn, Erin E. Gaughan, Beth Mills, Gareth O.S. Williams, James M. Stone, Keith Finlayson, Martine Chabaud-Riou, Florence Boudet, Kevin Dhaliwal, Vincent Pavot

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionPulmonary-resident memory T cells (TRM) and B cells (BRM) orchestrate protective immunity to reinfection with respiratory pathogens. Developing methods for the in situ detection of these populations would benefit both research and clinica

Externí odkaz: https://doaj.org/article/3f4db45336fc448c8b477921e7dd0a20

Resident Memory B Cells in Barrier Tissues

Autor: Choong Man Lee, Ji Eun Oh

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Epithelial barriers, which include the gastrointestinal, respiratory, and genitourinary mucosa, compose the body’s front line of defense. Since barrier tissues are persistently exposed to microbial challenges, a rapid response that can deal with di

Externí odkaz: https://doaj.org/article/c44c526d13b64d22873178744e46360b

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Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections

Autor: Vincent Pavot, Kevin Dhaliwal, Duncan Humphries, Richard A. O’Connor, Daniel Larocque, Martine Chabaud-Riou

Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Humphries, D C, O’connor, R A, Larocque, D, Chabaud-riou, M, Dhaliwal, K & Pavot, V 2021, ' Pulmonary-Resident Memory Lymphocytes: Pivotal Orchestrators of Local Immunity Against Respiratory Infections ', Frontiers in Immunology, vol. 12 . https://doi.org/10.3389/fimmu.2021.738955

There is increasing evidence that lung-resident memory T and B cells play a critical role in protecting against respiratory reinfection. With a unique transcriptional and phenotypic profile, resident memory lymphocytes are maintained in a quiescent s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905ccca739e486f62c3094aa3fc0e358
https://doi.org/10.3389/fimmu.2021.738955

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