Zobrazeno 1 - 10
of 2 198
pro vyhledávání: '"resident memory"'
Autor:
Xue-Wu Wei, Chang Lu, Yi-Chen Zhang, Xue Fan, Chong-Rui Xu, Zhi-Hong Chen, Fen Wang, Xiao-Rong Yang, Jia-Yi Deng, Ming-Yi Yang, Qing Gou, Shi-Qi Mei, Wei-Chi Luo, Ri-Wei Zhong, Wen-Zhao Zhong, Jin-Ji Yang, Xu-Chao Zhang, Hai-Yan Tu, Yi-Long Wu, Qing Zhou
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Metabolism reprogramming within the tumor microenvironment (TME) can have a profound impact on immune cells. Identifying the association between metabolic phenotypes and immune cells in lung adenocarcinoma (LUAD) may reveal mechanisms of resistance t
Externí odkaz:
https://doaj.org/article/69ff1c8e561c44988808d82daaa7d78f
Autor:
Mari Murakami
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-12 (2024)
Abstract Tissue-resident memory T cells (TRM) serve as the frontline of host defense, playing a critical role in protection against invading pathogens. This emphasizes their role in providing rapid on-site immune responses across various organs. The
Externí odkaz:
https://doaj.org/article/fa9f1d82823244c7a8352cd63398c40c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundLeukemia is a prevalent pediatric life-threatening hematologic malignancy with a poor prognosis. Targeting immune checkpoints (ICs) to reverse T cell exhaustion is a potentially effective treatment for leukemia. Tissue resident memory T (TR
Externí odkaz:
https://doaj.org/article/be6fc5d6b8e548439fd93cc285e6e06e
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Since CD4+ T cells are essential for regulating adaptive immune responses and for long lasting mucosal protection, changes in CD4+ T cell numbers and function are likely to affect protective immunity. What remains unclear is whether CD4+ T cell compo
Externí odkaz:
https://doaj.org/article/d5ec72daeb384a47b9b3b5980534d739
Autor:
Xiaoping Wu, Lai Yee Cheong, Lufengzi Yuan, Leigang Jin, Zixuan Zhang, Yang Xiao, Zhiguang Zhou, Aimin Xu, Ruby LC Hoo, Lingling Shu
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Type 1 diabetes (T1D) is a chronic disease characterized by self‐destruction of insulin‐producing pancreatic β cells by cytotoxic T cell activity. However, the pathogenic mechanism of T cell infiltration remains obscure. Recently, tissu
Externí odkaz:
https://doaj.org/article/2d1d40e92cea4a5db59baec244a2bdc8
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/7b3690a9a89046d1851082b26470bcbc
Publikováno v:
PeerJ, Vol 12, p e17667 (2024)
Advances in understanding the pathological mechanisms of breast cancer have resulted in the emergence of novel therapeutic strategies. However, triple-negative breast cancer (TNBC), a molecular subtype of breast cancer with a poor prognosis, lacks cl
Externí odkaz:
https://doaj.org/article/978038e65a734c81bf757a2a39d0cc84
Autor:
Aidan Shen, Aliesha Garrett, Cheng-Chi Chao, Dongliang Liu, Chao Cheng, Zhaohui Wang, Chen Qian, Yangzhi Zhu, Junhua Mai, Chongming Jiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance on the tumor-immune microenvironment (TIME) and tumor progression acro
Externí odkaz:
https://doaj.org/article/5997ee97a822453ab95d8ce4ff25267d
Autor:
Ao Zeng, Yanze Yin, Zhilong Xu, Abudumijiti Abuduwayiti, Fujun Yang, Mohammed Saud Shaik, Chao Wang, Keyi Chen, Xinyun Fang, Jie Dai
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Emerging data suggested a favorable outcome in advanced non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease (COPD) patients treated by immunotherapy. The objective of this study was to investigate the eff
Externí odkaz:
https://doaj.org/article/14bbda9f96f04cbb8986cffbc7022727
Autor:
Jialing Fang, Jun Lei, Boxiao He, Yankang Wu, Peng Chen, Zaiqiao Sun, Ning Wu, Yafei Huang, Pengcheng Wei, Lei Yin, Yongshun Chen
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Resident memory T (Trm) cells which are specifically located in non-lymphoid tissues showed distinct phenotypes and functions compared to circulating memory T cells and were vital for the initiation of robust immune response within tissues.
Externí odkaz:
https://doaj.org/article/36d6b28360534518916084c0cdbae9ae